Atmospheric Pressure plAsma meets biomaterials for bone Cancer HEaling

Project Information

APACHE

Grant agreement ID: 714793

DOI

10.3030/714793

Project closed

EC signature date 15 March 2017

Start date 1 April 2017

End date 31 December 2022

Funded under

• EXCELLENT SCIENCE - European Research Council (ERC)

Total cost

€ 1 499 887,00

EU contribution

€ 1 499 887,00

Coordinated by

UNIVERSITAT POLITECNICA DE CATALUNYA
Spain

CORDIS provides links to public deliverables and publications of HORIZON projects.

Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Publications

Peer reviewed articles (19)

Evaluation of the effects of cold atmospheric plasma and plasma-treated liquids in cancer cell cultures

Author(s): Juan Tornin, Cédric Labay, Francesco Tampieri, Maria-Pau Ginebra, Cristina Canal
Published in: Nature Protocols, Issue 16/6, 2021, Page(s) 2826-2850, ISSN 1754-2189
Publisher: Nature Publishing Group
DOI: 10.1038/s41596-021-00521-5

Cold atmospheric plasma enhances doxorubicin selectivity in metastasic bone cancer

Author(s): Miguel Mateu-Sanz; María-Pau Ginebra; Juan Tornín; Cristina Canal
Published in: instname:Universitat Politècnica de Catalunya (UPC), Issue 189, 2022, Page(s) 32-41, ISSN 0891-5849
Publisher: Elsevier BV
DOI: 10.1016/j.freeradbiomed.2022.07.007

Ceramic‐hydrogel composite as carrier for cold‐plasma reactive‐species: Safety and osteogenic capacity in vivo

Author(s): Xavi Solé‐Martí; Cédric Labay; Yago Raymond; Jordi Franch; Raul Benitez; Maria‐Pau Ginebra; Cristina Canal
Published in: Plasma Processes and Polymers, Issue 20, 2023, Page(s) e2200155, ISSN 1612-8850
Publisher: Wiley - V C H Verlag GmbbH & Co.
DOI: 10.1002/ppap.202200155

Cold Atmospheric Plasma: A New Strategy Based Primarily on Oxidative Stress for Osteosarcoma Therapy

Author(s): Miguel Mateu-Sanz, Juan Tornin, Maria-Pau Ginebra, Cristina Canal
Published in: J. Clin. Med., Issue 10, 2021, Page(s) 893, ISSN 2077-0383
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/jcm10040893

Osteosarcoma tissue-engineered model challenges oxidative stress therapy revealing promoted cancer stem cell properties

Author(s): Juan Tornín, Aranzazu Villasante, Xavi Solé-Martí, Maria-Pau Ginebra, Cristina Canal
Published in: Free Radical Biology and Medicine, Issue 164, 2021, Page(s) 107-118, ISSN 0891-5849
Publisher: Elsevier BV
DOI: 10.1016/j.freeradbiomed.2020.12.437

Current State of Cold Atmospheric Plasma and Cancer-Immunity Cycle: Therapeutic Relevance and Overcoming Clinical Limitations Using Hydrogels

Author(s): Milica Živanić, Albert Espona-Noguera, Abraham Lin, Cristina Canal
Published in: Advanced Science, 2023, Page(s) 2205803, ISSN 2198-3844
Publisher: John Wiley & Sons
DOI: 10.1002/advs.202205803

Can we remove tattoos with non-thermal atmospheric plasma?

Author(s): Francesco Tampieri; Ariadna G. Araguz; Cristina Canal
Published in: PLASMA PROCESSES AND POLYMERS, Issue 2, 2022, Page(s) e2100188, ISSN 1612-8850
Publisher: Wiley - V C H Verlag GmbbH & Co.
DOI: 10.1002/ppap.202100188

Plasma-induced selectivity in bone cancer cells death

Author(s): Cristina Canal, Raul Fontelo, Ines Hamouda, Jordi Guillem-Marti, Uros Cvelbar, Maria-Pau Ginebra
Published in: Free Radical Biology and Medicine, Issue 110, 2017, Page(s) 72-80, ISSN 0891-5849
Publisher: Elsevier BV
DOI: 10.1016/j.freeradbiomed.2017.05.023

Important parameters in plasma jets for the production of RONS in liquids for plasma medicine: A brief review

Author(s): Anna Khlyustova, Cédric Labay, Zdenko Machala, Maria-Pau Ginebra, Cristina Canal
Published in: Frontiers of Chemical Science and Engineering, Issue 13/2, 2019, Page(s) 238-252, ISSN 2095-0179
Publisher: Higher Education Press
DOI: 10.1007/s11705-019-1801-8

Generation Of Reactive Species By Plasma Needle In Different Liquids

Author(s): Inés Hamouda, Alix Gouhier, Cédric Labay, Maria-Pau Ginebra, Cristina Canal
Published in: Clinical Plasma Medicine, Issue 9, 2018, Page(s) 34-35, ISSN 2212-8166
Publisher: Elsevier GmbH
DOI: 10.1016/j.cpme.2017.12.054

Pyruvate Plays a Main Role in the Antitumoral Selectivity of Cold Atmospheric Plasma in Osteosarcoma

Author(s): Juan Tornin, Miguel Mateu-Sanz, Aida Rodríguez, Cédric Labay, Rene Rodríguez, Cristina Canal
Published in: Scientific Reports, Issue 9/1, 2019, ISSN 2045-2322
Publisher: Nature Publishing Group
DOI: 10.1038/s41598-019-47128-1

Production of reactive species in alginate hydrogels for cold atmospheric plasma-based therapies

Author(s): Cédric Labay, Inès Hamouda, Francesco Tampieri, Maria-Pau Ginebra, Cristina Canal
Published in: Scientific Reports, Issue 9/1, 2019, Page(s) 16160, ISSN 2045-2322
Publisher: Nature Publishing Group
DOI: 10.1038/s41598-019-52673-w

Cold Plasma-Treated Ringer’s Saline: A Weapon to Target Osteosarcoma

Author(s): Miguel Mateu-Sanz, Juan Tornín, Bénédicte Brulin, Anna Khlyustova, Maria-Pau Ginebra, Pierre Layrolle, Cristina Canal
Published in: Cancers, Issue 12/1, 2020, Page(s) 227, ISSN 2072-6694
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/cancers12010227

Investigating the atmospheric pressure plasma jet modification of a photo-crosslinkable hydrogel

Author(s): Inès Hamouda, Cédric Labay, Maria Pau Ginebra, Erwan Nicol, Cristina Canal
Published in: Polymer, Issue 192, 2020, Page(s) 122308, ISSN 0032-3861
Publisher: Elsevier BV
DOI: 10.1016/j.polymer.2020.122308

Selectivity of direct plasma treatment and plasma-conditioned media in bone cancer cell lines

Author(s): Inès Hamouda, Cédric Labay, Uroš Cvelbar, Maria-Pau Ginebra, Cristina Canal
Published in: Scientific Reports, Issue 11/1, 2021, Page(s) All, ISSN 2045-2322
Publisher: Nature Publishing Group
DOI: 10.1038/s41598-021-96857-9

Quantification of Plasma-Produced Hydroxyl Radicals in Solution and their Dependence on the pH

Author(s): Francesco Tampieri, Maria-Pau Ginebra, Cristina Canal
Published in: Analytical Chemistry, Issue 93/8, 2021, Page(s) 3666-3670, ISSN 0003-2700
Publisher: American Chemical Society
DOI: 10.1021/acs.analchem.0c04906

Plasma-Conditioned Liquids as Anticancer Therapies In Vivo: Current State and Future Directions

Author(s): Xavi Solé-Martí, Albert Espona-Noguera, Maria-Pau Ginebra, Cristina Canal
Published in: Cancers, Issue 13/3, 2021, Page(s) 452, ISSN 2072-6694
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/cancers13030452

Enhanced Generation of Reactive Species by Cold Plasma in Gelatin Solutions for Selective Cancer Cell Death

Author(s): Cédric Labay, Marcel Roldán, Francesco Tampieri, Augusto Stancampiano, Pablo Escot Bocanegra, Maria-Pau Ginebra, Cristina Canal
Published in: ACS Applied Materials & Interfaces, Issue 12/42, 2020, Page(s) 47256-47269, ISSN 1944-8244
Publisher: American Chemical Society
DOI: 10.1021/acsami.0c12930

Thermosensitive hydrogels to deliver reactive species generated by cold atmospheric plasma: a case study with methylcellulose

Author(s): Xavi Solé-Martí; Tània Vilella; Cédric Labay; Francesco Tampieri; Maria-Pau Ginebra; Cristina Canal
Published in: Biomaterials Science, Issue 10, 2022, Page(s) 3845, ISSN 2047-4830
Publisher: Royal Society of Chemistry
DOI: 10.1039/d2bm00308b

Non-peer reviewed articles (1)

Application of Plasma Technology in Bioscience and Biomedicine

Author(s): Daniela Boehm, Cristina Canal
Published in: Applied Sciences, Issue 11/16, 2021, Page(s) 7203, ISSN 2076-3417
Publisher: Basel, Switzerland
DOI: 10.3390/app11167203

Conference proceedings (6)

Influence of the composition of plasma-activated medium on osteosarcoma

Author(s): Cristina Canal, Juan Tornín, Miguel Mateu, Inés Hamouda, Cédric Labay, Jordi Guillem, Maria-Pau Ginebra
Published in: International Conference on Plasma Medicine (ICPM7) Book of abstracts, Issue 7, 2018
Publisher: International Society on Plasma Medicine

Influence of process parameters in the generation of reactive oxygen and nitrogen species in cell culture media by atmospheric pressure plasma jet

Author(s): Canal Barnils, Cristina; Humbert, Marjolaine; Guillem Martí, Jordi; Ginebra Molins, Maria Pau
Published in: International Conference on Plasmas with liquids (ICPL2017) Book of abstracts, Issue 2, 2017, Page(s) 109, ISBN 978-80-87026-07-6
Publisher: Organization of ICPL 2017

Liquid-mediated effects of cold plasma on bone cancer

Author(s): Canal Barnils, Cristina; Hamouda, Ines; Guillem Martí, Jordi; Ginebra Molins, Maria Pau
Published in: "Book of abstracts - International Symposium on Plasma Nanoscience and Nanotechnology. ""iPlasmaNano-VIII 2017""", Issue 1, 2017, Page(s) 68
Publisher: University of Antwerp

Modification of hydrogel-based biomaterials by atmospheric pressure plasma to enhance tissue regeneration

Author(s): Cédric Labay, Inés Hamouda, Maria-Pau Ginebra, Cristina Canal
Published in: 7th International Conference on Plasma Medicine (ICPM7) Book of abstracts, Issue 1, 2018, Page(s) 4
Publisher: International Society on Plasma Medicine

Plasma jet selectivity on bone cancer cells and liquid-mediated effects

Author(s): Canal Barnils, Cristina; Humbert, Marjolaine; Guillem Martí, Jordi; Ginebra Molins, Maria Pau
Published in: International Workshop on Plasma for Cancer Treatment - Book of Abstracts, Issue 1, 2017, Page(s) 34
Publisher: International Workshop on Plasma for Cancer Treatment

Modification of hydrogel-based biomaterials by atmospheric pressure plasma to enhance tissue regeneration

Author(s): Cédric Labay,Inès Hamouda, Maria Pau Ginebra, Cristina Canal
Published in: International Conference on Plasma Medicine (ICPM7) Book of abstracts, 2018
Publisher: International Society of Plasma