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Evolving interactions in microbial communities

Objective

Microbes play an important role in various aspects of our lives, from our own health to the health of our environment. In almost all of their natural habitats, microbes live in dense communities composed of different strains and species that interact with each other. As these microbes evolve, so do the interactions between them, which alters the functioning of the community as a whole.

In this project, I propose to develop theoretical and experimental tools to study and control evolving interactions between cells and species living in microbial ecosystems. This will involve three main research objectives: first, we will couple theory and experiments to disentangle and characterise the social interactions between five bacterial species that make up an ecosystem used to degrade pollutants. Our second objective will be to use this knowledge to control this same ecosystem, by directing it toward increased productivity and stability. Finally, our third objective will be to “breed” novel communities from scratch using experimental evolution to promote cooperative interactions between community members and thereby increase productivity.

This interdisciplinary and ambitious research will allow us to improve existing methods in pollution degradation, and to design new microbial communities for this and other purposes. More generally, our model system will provide an in-depth conceptual understanding of microbial ecosystems and their evolution, and the tools to investigate more complex microbial communities. My ultimate vision is to possess the technology to use microbial communities to degrade waste, generate efficient biofuels, and design customised treatments for intestinal diseases. This project promises to create the foundations needed to develop this technology, and open many exciting avenues for future research.

Fields of science (EuroSciVoc)

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Programme(s)

Multi-annual funding programmes that define the EU’s priorities for research and innovation.

Topic(s)

Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.

Funding Scheme

Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.

ERC-STG - Starting Grant

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Call for proposal

Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.

(opens in new window) ERC-2016-STG

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Host institution

UNIVERSITE DE LAUSANNE
Net EU contribution

Net EU financial contribution. The sum of money that the participant receives, deducted by the EU contribution to its linked third party. It considers the distribution of the EU financial contribution between direct beneficiaries of the project and other types of participants, like third-party participants.

€ 1 498 875,00
Address
QUARTIER UNIL CENTRE - BATIMENT UNICENTRE
1015 LAUSANNE
Switzerland

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Region
Schweiz/Suisse/Svizzera Région lémanique Vaud
Activity type
Higher or Secondary Education Establishments
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Total cost

The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.

€ 1 498 875,00

Beneficiaries (1)

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