Microglia action towards neuronal circuit formation and function in health and disease

Project Information

MICROGLIA-CIRCUIT

Grant agreement ID: 715571

DOI

10.3030/715571

Project closed

EC signature date 15 February 2017

Start date 1 May 2017

End date 31 October 2022

Funded under

• EXCELLENT SCIENCE - European Research Council (ERC)

Total cost

€ 1 500 000,00

EU contribution

€ 1 500 000,00

Coordinated by

INSTITUTE OF SCIENCE AND TECHNOLOGY AUSTRIA
Austria

CORDIS provides links to public deliverables and publications of HORIZON projects.

Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Publications

Peer reviewed articles (6)

Optimizing AAV2/6 microglial targeting identified enhanced efficiency in the photoreceptor degenerative environment

Author(s): Margaret E. Maes, Gabriele M. Wögenstein, Gloria Colombo, Raquel Casado-Polanco, Sandra Siegert
Published in: Molecular Therapy - Methods & Clinical Development, Issue 23, 2021, Page(s) 210-224, ISSN 2329-0501
Publisher: Cell Press
DOI: 10.1016/j.omtm.2021.09.006

A tool for mapping microglial morphology, morphOMICs, reveals brain-region and sex-dependent phenotypes

Author(s): Gloria Colombo, Ryan John A. Cubero, Lida Kanari, Alessandro Venturino, Rouven Schulz, Martina Scolamiero, Jens Agerberg, Hansruedi Mathys, Li-Huei Tsai, Wojciech Chachólski, Kathryn Hess & Sandra Siegert
Published in: Nature Neuroscience, Issue 25, 2022, Page(s) 1379–1393, ISSN 1097-6256
Publisher: Nature Publishing Group
DOI: 10.1038/s41593-022-01167-6

Microglia enable mature perineuronal nets disassembly upon anesthetic ketamine exposure or 60-Hz light entrainment in the healthy brain

Author(s): Alessandro Venturino, Rouven Schulz, Héctor De Jesús-Cortés, Margaret E. Maes, Bálint Nagy, Francis Reilly-Andújar, Gloria Colombo, Ryan John A. Cubero, Florianne E. Schoot Uiterkamp, Mark F. Bear, Sandra Siegert
Published in: Cell Reports, Issue 36/1, 2021, Page(s) 109313, ISSN 2211-1247
Publisher: Cell Press
DOI: 10.1016/j.celrep.2021.109313

Targeting microglia with lentivirus and AAV: Recent advances and remaining challenges

Author(s): Margaret E. Maes, Gloria Colombo, Rouven Schulz, Sandra Siegert
Published in: Neuroscience Letters, Issue 707, 2019, Page(s) 134310, ISSN 0304-3940
Publisher: Elsevier BV
DOI: 10.1016/j.neulet.2019.134310

A systematic characterization of microglia-like cell occurrence during retinal organoid differentiation

Author(s): Katarina Bartalska, Verena Hübschmann, Medina Korkut-Demirbaş, Ryan John A. Cubero, Alessandro Venturino, Karl Rössler, Thomas Czech, Sandra Siegert
Published in: iScience, Issue Volume 25, Issue 7, 2022, ISSN 2589-0042
Publisher: Cell Press
DOI: 10.1016/j.isci.2022.104580

Assessing human iPSC-derived microglia identity and function by immunostaining, phagocytosis, calcium activity, and inflammation assay

Author(s): Verena Hübschmann, Medina Korkut-Demirbaş, Sandra Siegert
Published in: STAR Protocols, Issue 3, 4, 2022, ISSN 2666-1667
Publisher: Cell Press
DOI: 10.1016/j.xpro.2022.101866