STEM CELL MODELS TO UNRAVEL THE SUSCEPTIBILITY AND RESILIENCE TO DEVELOP HEART FAILURE

Project Information

STOP-HF

Grant agreement ID: 715732

DOI

10.3030/715732

Project closed

EC signature date 17 February 2017

Start date 1 March 2017

End date 28 February 2022

Funded under

• EXCELLENT SCIENCE - European Research Council (ERC)

Total cost

€ 1 496 875,00

EU contribution

€ 1 496 875,00

Coordinated by

ACADEMISCH ZIEKENHUIS GRONINGEN
Netherlands

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Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Publications

Peer reviewed articles (4)

Gain-of-function mutation in ubiquitin ligase KLHL24 causes desmin degradation and dilatation in hiPSC-derived engineered heart tissues

Author(s): Mathilde C.S.C. Vermeer, Maria C. Bolling, Jacqueline M. Bliley, Karla F. Arevalo Gomez, Mario G. Pavez-Giani, Duco Kramer, Pedro H. Romero-Herrera, B. Daan Westenbrink, Gilles F.H. Diercks, Maarten P. van den Berg, Adam W. Feinberg, Herman H.W. Silljé, Peter van der Meer
Published in: JCI The Journal of Clinical Investigation, 2021, ISSN 0021-9738
Publisher: American Society for Clinical Investigation
DOI: 10.1172/jci140615

Dynamic loading of human engineered heart tissue enhances contractile function and drives a desmosome-linked disease phenotype

Author(s): JACQUELINE M. BLILEY, MATHILDE C. S. C. VERMEER, REBECCA M. DUFFYI, VAN BATALOV, DUCO KRAMER, JOSHUA W. TASHMAN, DANIEL J. SHIWARSKI, ANDREW LEE, ALEXANDER S. TEPLENIN, LINDA VOLKERS, BRIAN COFFIN, MARTIJN F. HOES, ANNA KALMYKOV, RACHELLE N. PALCHESKO, YAN SUN, JAN D. H. JONGBLOED, NILS BOMER, RUDOLF A. DE BOER, ALBERT J. H. SUURMEIJER, DANIEL A. PIJNAPPELS, MARIA C. BOLLING, PETER VAN DER MEER,
Published in: Science Translational Medicine, Issue 19466234, 2021, ISSN 1946-6234
Publisher: American Association for the Advancement of Science
DOI: 10.1126/scitranslmed.abd1817

Pathophysiology and risk factors of peripartum cardiomyopathy

Author(s): Martijn F. Hoes, Zoltan Arany, Johann Bauersachs, Denise Hilfiker-Kleiner, Mark C. Petrie, Karen Sliwa, Peter van der Meer
Published in: nature reviews cardiology, Issue 17595002, 2022, ISSN 1759-5002
Publisher: Nature Publishing Group
DOI: 10.1038/s41569-021-00664-8

Human iPSC-Derived Cardiomyocytes of Peripartum Patients With Cardiomyopathy Reveal Aberrant Regulation of Lipid Metabolism

Author(s): Martijn F. Hoes, Nils Bomer, Melanie Ricke-Hoch, Tristan V. de Jong, Karla F. Arevalo Gomez, Stefan Pietzsch, Denise Hilfiker-Kleiner, Peter van der Meer
Published in: American Heart Association Journals - Circulation, Issue 00097322, 2020, ISSN 0009-7322
Publisher: Lippincott Williams & Wilkins Ltd.
DOI: 10.1161/circulationaha.119.044962