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Defining novel mechanisms critical for colorectal tumourigenesis

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Publications

Negative regulation of TGFβ-induced apoptosis by RAC1B enhances intestinal tumourigenesis

Author(s): Victoria Gudiño 1 2 , Patrizia Cammareri 1 , Caroline V Billard 1 , Kevin B Myant 3
Published in: Cell Death and Disease, 2021, ISSN 2041-4889
Publisher: Nature Publishing Group
DOI: 10.1038/s41419-021-04177-7

A role for endothelial nitric oxide synthase in intestinal stem cell proliferation and mesenchymal colorectal cancer

Author(s): Jon Peñarando, Laura M. López-Sánchez, Rafael Mena, Silvia Guil-Luna, Francisco Conde, Vanessa Hernández, Marta Toledano, Victoria Gudiño, Michela Raponi, Caroline Billard, Carlos Villar, César Díaz, José Gómez-Barbadillo, Juan De la Haba-Rodríguez, Kevin Myant, Enrique Aranda, Antonio Rodríguez-Ariza
Published in: BMC Biology, Issue 16/1, 2018, ISSN 1741-7007
Publisher: BioMed Central
DOI: 10.1186/s12915-017-0472-5

Aspirin Rescues Wnt-Driven Stem-like Phenotype in Human Intestinal Organoids and Increases the Wnt Antagonist Dickkopf-1

Author(s): Karen Dunbar, Asta Valanciute, Ana Lima, Paz Freile Vinuela, Thomas Jamieson, Vidya Rajasekaran, James Blackmur, Anna-Maria Ochocka-Fox, Alice Guazzelli, Patrizia Cammareri, Mark J. Arends, Owen J. Sansom, Kevin B. Myant, Susan M. Farrington, Malcolm G. Dunlop, Farhat V.N. Din
Published in: Cellular and Molecular Gastroenterology and Hepatology, 2020, ISSN 2352-345X
Publisher: Elsevier Inc.
DOI: 10.1016/j.jcmgh.2020.09.010

RAC1B modulates intestinal tumourigenesis via modulation of WNT and EGFR signalling pathways

Author(s): Victoria Gudiño 1 2 , Sebastian Öther-Gee Pohl 1 , Caroline V Billard 1 , Patrizia Cammareri 1 , Alfonso Bolado 1 , Stuart Aitken 3 4 , David Stevenson 5 , Adam E Hall 1 , Mark Agostino 6 7 , John Cassidy 8 , Colin Nixon 5 , Alex von Kriegsheim 1 , Paz Freile 1 3 4 , Linda Popplewell 9 , George Dickson 9 , Laura Murphy 4 , Ann Wheeler 4 , Malcolm Dunlop 1 3 4 , Fa
Published in: Nature Communications, 2021, ISSN 2041-1723
Publisher: Nature Publishing Group
DOI: 10.1038/s41467-021-22531-3

RNA splicing is a key mediator of tumour cell plasticity and a therapeutic vulnerability in colorectal cancer

Author(s): Adam E Hall, Sebastian Öther-Gee Pohl, Patrizia Cammareri, Stuart Aitken, Nicholas T Younger, Michela Raponi, Caroline V Billard, Alfonso Bolado Carrancio, Aslihan Bastem , Paz Freile, Fiona Haward, Ian R Adams, Javier F Caceres, Paula Preyzner, Alex von Kriegsheim, Malcolm G Dunlop, Farhat V Din , Kevin B Myant
Published in: Nature Communications, 2022, ISSN 2041-1723
Publisher: Nature Publishing Group
DOI: 10.1038/s41467-022-30489-z

Alternative RNA splicing in tumour heterogeneity, plasticity and therapy

Author(s): Sebastian Öther-Gee Pohl 1 , Kevin B Myant 1
Published in: Disease Models and Mechanisms, 2022, ISSN 1754-8411
Publisher: The Company of Biologists
DOI: 10.1242/dmm.049233

A RAC-GEF network critical for early intestinal tumourigenesis

Author(s): K A Pickering 1 , K Gilroy 1 , J W Cassidy 2 , S K Fey 1 3 , A K Najumudeen 1 , L B Zeiger 1 3 , D F Vincent 1 , D M Gay 1 , J Johansson 1 , R P Fordham 1 , B Miller 1 , W Clark 1 , A Hedley 1 , E B Unal 4 5 6 , C Kiel 4 , E McGhee 1 , L M Machesky 1 3 , C Nixon 1 , A E Johnsson 7 , M Bain 8 , D Strathdee 1 , S R van Hoof 9 10 , J P Medema 9 10 , K I Anderson
Published in: Nature Communications, 2021, ISSN 2041-1723
Publisher: Nature Publishing Group
DOI: 10.1038/s41467-020-20255-4

Be like water, my cells: cell plasticity and the art of transformation

Author(s): Patrizia Cammareri and Kevin Myant
Published in: Frontiers in Cell and Developmental Biology, Issue 2023 Oct 11:11:1272730, 2023, ISSN 2296-634X
Publisher: Frontiers

COLGENES - Defining novel mechanisms critical for colorectal tumourigenesis

Author(s): Kevin Myant
Published in: Impact, Issue 2017/10, 2017, Page(s) 12-14, ISSN 2398-7073
Publisher: Science Impact Ltd
DOI: 10.21820/23987073.2017.10.12

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