Heart regeneration in the Mexican cavefish: The difference between healing and scarring

Project Information

CAVEHEART

Grant agreement ID: 715895

DOI 10.3030/715895

Project closed

EC signature date 25 November 2016

Start date 1 March 2017

End date 31 August 2022

Funded under

• EXCELLENT SCIENCE - European Research Council (ERC)

Total cost € 1 499 429,00

EU contribution € 1 499 429,00

Coordinated by

THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD
United Kingdom

Publications

Peer reviewed articles (7)

Unlocking the Secrets of the Regenerating Fish Heart: Comparing Regenerative Models to Shed Light on Successful Regeneration

Author(s): Helen G. Potts, William T. Stockdale, Mathilda T. M. Mommersteeg
Published in: Journal of Cardiovascular Development and Disease, Issue 8/1, 2021, Page(s) 4, ISSN 2308-3425
Publisher: MDPI
DOI: 10.3390/jcdd8010004

Discordant Genome Assemblies Drastically Alter the Interpretation of Single-Cell RNA Sequencing Data Which Can Be Mitigated by a Novel Integration Method

Author(s): Helen G. Potts, Madeleine E. Lemieux, Edward S. Rice, Wesley Warren, Robin P. Choudhury and Mathilda T. M. Mommersteeg
Published in: Cells, Issue 20734409, 2022, ISSN 2073-4409
Publisher: Basel MDPI AG 2012-
DOI: 10.3390/cells11040608

The developmental origin of heart size and shape differences in Astyanax mexicanus populations

Author(s): Jocelyn L.Y. Tang, Yu Guo, William T. Stockdale, Kerisha Rana, Abigail C. Killen, Mathilda T.M. Mommersteeg, Yoshiyuki Yamamoto
Published in: Developmental Biology, Issue 441/2, 2018, Page(s) 272-284, ISSN 0012-1606
Publisher: Academic Press
DOI: 10.1016/j.ydbio.2018.06.009

Heart Regeneration in the Mexican Cavefish

Author(s): William T. Stockdale, Madeleine E. Lemieux, Abigail C. Killen, Juanjuan Zhao, Zhilian Hu, Joey Riepsaame, Noémie Hamilton, Tetsuhiro Kudoh, Paul R. Riley, Ronny van Aerle, Yoshiyuki Yamamoto, Mathilda T.M. Mommersteeg
Published in: Cell Reports, Issue 25/8, 2018, Page(s) 1997-2007.e7, ISSN 2211-1247
Publisher: Cell Press
DOI: 10.1016/j.celrep.2018.10.072

Runx1 promotes scar deposition and inhibits myocardial proliferation and survival during zebrafish heart regeneration

Author(s): Jana Koth, Xiaonan Wang, Abigail C. Killen, William T. Stockdale, Helen G. Potts, Andrew Jefferson, Florian Bonkhofer, Paul R. Riley, Roger K. Patient, Berthold Göttgens, Mathilda T. M. Mommersteeg
Published in: Development, Issue 147/8, 2020, Page(s) dev186569, ISSN 0950-1991
Publisher: The Company of Biologists Ltd.
DOI: 10.1242/dev.186569

Talkin’ ‘bout regeneration: new advances in cardiac regeneration using the zebrafish

Author(s): Kelly A Smith, Mathilda TM Mommersteeg
Published in: Current Opinion in Physiology, Issue 14, 2020, Page(s) 48-55, ISSN 2468-8673
Publisher: Elsevier
DOI: 10.1016/j.cophys.2019.12.016

A chromosome-level genome of Astyanax mexicanus surface fish for comparing population-specific genetic differences contributing to trait evolution

Author(s): Wesley C. Warren, Tyler E. Boggs, Richard Borowsky, Brian M. Carlson, Estephany Ferrufino, Joshua B. Gross, LaDeana Hillier, Zhilian Hu, Alex C. Keene, Alexander Kenzior, Johanna E. Kowalko, Chad Tomlinson, Milinn Kremitzki, Madeleine E. Lemieux, Tina Graves-Lindsay, Suzanne E. McGaugh, Jeffrey T. Miller, Mathilda T. M. Mommersteeg, Rachel L. Moran, Robert Peuß, Edward S. Rice, Misty R. Riddle, I
Published in: Nature Communications, Issue 12/1, 2021, ISSN 2041-1723
Publisher: Nature Publishing Group
DOI: 10.1038/s41467-021-21733-z