Biological auto-detection and termination of heart rhythm disturbances

Project Information

Bio-ICD

Grant agreement ID: 716509

DOI

10.3030/716509

Project closed

EC signature date 15 December 2016

Start date 1 March 2017

End date 28 February 2023

Funded under

• EXCELLENT SCIENCE - European Research Council (ERC)

Total cost

€ 1 485 028,00

EU contribution

€ 1 485 028,00

Coordinated by

ACADEMISCH ZIEKENHUIS LEIDEN
Netherlands

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Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Publications

Peer reviewed articles (7)

The Effects of Repetitive Use and Pathological Remodeling on Channelrhodopsin Function in Cardiomyocytes

Author(s): Balzs rdg, Alexander Teplenin, Tim De Coster, Cindy I Bart, Sven O Dekker, Juan Zhang, Dirk L Ypey, Antoine A F de Vries, Danil A Pijnappels
Published in: Frontiers in Physiology, 2021, ISSN 1664-042X
Publisher: Frontiers Research Foundation
DOI: 10.3389/fphys.2021.710020

Optical ventricular cardioversion by local optogenetic targeting and LED implantation in a cardiomyopathic rat model.

Author(s): E.C.A. Nyns; Tianyi Jin; Magda S Fontes; Titus van den Heuvel; Vincent Portero; Catilin Ramsey; Cindy I. Bart; Katja Zeppenfeld; Martin J. Schalij; Thomas J van Brakel; Arti A. Ramkisoensing; Guoqi Zhang; R. H. Poelma; Balázs Ördög; Antoine A.F. de Vries; Daniël A. Pijnappels
Published in: Cardiovascular Research, 118(10), Issue 1, 2022, ISSN 1755-3245
Publisher: Oxford University Press
DOI: 10.1093/cvr/cvab294

Optogenetics enables real-time spatiotemporal control over spiral wave dynamics in an excitable cardiac system

Author(s): Rupamanjari Majumder, Iolanda Feola, Alexander S Teplenin, Antoine AF de Vries, Alexander V Panfilov, Daniel A Pijnappels
Published in: eLife, Issue 7, 2018, ISSN 2050-084X
Publisher: eLife Sciences Publications
DOI: 10.7554/eLife.41076

Biological defibrillation

Author(s): Emile C A Nyns, Antoine A F de Vries, Daniël A Pijnappels
Published in: European Heart Journal, Issue 39/44, 2018, Page(s) 3915-3917, ISSN 0195-668X
Publisher: Oxford University Press
DOI: 10.1093/eurheartj/ehy689

An automated hybrid bioelectronic system for autogenous restoration of sinus rhythm in atrial fibrillation

Author(s): Emile C. A. Nyns, René H. Poelma, Linda Volkers, Jaap J. Plomp, Cindy I. Bart, Annemarie M. Kip, Thomas J. van Brakel, Katja Zeppenfeld, Martin J. Schalij, Guo Qi Zhang, Antoine A. F. de Vries, Daniël A. Pijnappels
Published in: Science Translational Medicine, Issue 11/481, 2019, Page(s) eaau6447, ISSN 1946-6234
Publisher: American Association for the Advancement of Science
DOI: 10.1126/scitranslmed.aau6447

Self-restoration of cardiac excitation rhythm by anti-arrhythmic ion channel gating.

Author(s): Rupamanjari Majumder; Tim De Coster; Nina Kudryashova; Arie O Verkerk; Ivan V Kazbanov; Balázs Ördög; Niels Harlaar; Ronald Wilders; Antoine AF de Vries; Dirk L Ypey; Alexander V Panfilov; Daniël A Pijnappels
Published in: eLife, Issue 2, 2020, ISSN 2050-084X
Publisher: eLife Sciences Publications
DOI: 10.7554/elife.55921

The heart as its own defibrillator

Author(s): Daniël A Pijnappels
Published in: European Heart Journal, Issue 41/30, 2020, Page(s) 2829-2832, ISSN 0195-668X
Publisher: Oxford University Press
DOI: 10.1093/eurheartj/ehaa609

Thesis and dissertations (1)

Optogenetic investigation of cardiac arrhythmia mechanisms

Author(s): Iolanda Feola
Published in: 2018
Publisher: Own

Book chapters (1)

Optogenetics for cardiac pacing, resynchronization, and arrhythmia termination.

Author(s): Antoine de Vries, Udi Nuwwinovitch, Philipp Sasse, Tobias Brugmann, Emile Nyns, Daniel Pijnappels
Published in: 2020
Publisher: Elsevier