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Development and validation of an innovative nutritional solution to fight muscle atrophy during human space flights, application of the acquired knowledge to prevent muscle degeneration down on earth

Objective

Question: What is the common factor between an astronaut, an older person and someone who just underwent a serious surgery? Answer: Muscle atrophy. During long missions for instance, astronauts can lose up to 50% of their muscle mass severely affecting their performance and health. The only commercially available solutions hardly able to mitigate the effect of weightlessness, ageing and immobilization are exercise and diet but they are not satisfactory in terms of efficiency, ease-of-use, bioavailability, compliancy or scientific backing. AstroCIT’s objective is to develop and validate an innovative nutraceutical to fight muscle loss during human space flights and prevent muscular degeneration on earth. It will revolutionize how muscle atrophy is cared for by giving space physicians, gerontologists and physiotherapists an effective preventive and therapeutic solution, thereby enabling astronauts to be more operational, bettering quality of life in space, improving autonomy of aged or injured people and reducing public spending. This new nutraceutical is based on CITRAGE’s and its partners’ long lasting expertise in developing and commercializing amino acids based products applied to the combination of a proven and a hitherto unseen compounds. During phase 1, CITRAGE will scale-up the project by (a) defining the best formulation and galenics for the product, (b) accessing data generated by other research projects in the field of nutrition and muscle atrophy, (c) collecting medical and financial data to further quantify the technology’s benefit and its risks, (d) defining the protocol of a EU clinical study to be implemented in phase 2 and (e) consolidating the IP strategy. The main deliverable will be an updated business plan enabling CITRAGE to seize this huge business opportunity of further exploiting their know-how in space and down on earth. This feasibility study is an essential first step before routine use and industrial production.

Fields of science (EuroSciVoc)

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Programme(s)

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Topic(s)

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Funding Scheme

Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.

SME-1 - SME instrument phase 1

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Call for proposal

Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.

(opens in new window) H2020-SMEInst-2014-2015

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Coordinator

CITRAGE
Net EU contribution

Net EU financial contribution. The sum of money that the participant receives, deducted by the EU contribution to its linked third party. It considers the distribution of the EU financial contribution between direct beneficiaries of the project and other types of participants, like third-party participants.

€ 50 000,00
Address
94 AV GENERAL DE GAULLE
94019 CRETEIL
France

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SME

The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.

Yes
Region
Ile-de-France Ile-de-France Val-de-Marne
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
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Total cost

The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.

€ 71 429,00
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