New siRNA Nanotherapy for Inflammatory Bowel Diseases, targeting Janus kinases

Información del proyecto

NEW DEAL

Identificador del acuerdo de subvención: 720905

DOI 10.3030/720905

Proyecto cerrado

Fecha de la firma de la CE 9 Noviembre 2016

Fecha de inicio 1 Enero 2017

Fecha de finalización 30 Septiembre 2021

Financiado con arreglo a

• INDUSTRIAL LEADERSHIP - Leadership in enabling and industrial technologies – Nanotechnologies

Coste total € 5 999 178,75

Aportación de la UE € 5 999 178,75

Coordinado por

COMMISSARIAT A L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES
France

Resultado final

Websites, patent fillings, videos etc. (3)

Outcomes video

SCS will produce a video to showcase the key outcomes of the project to be shown at the final conference and to be distributed by partners and via social platforms

Basic communication tools

SPARKS will provide Logo, leaflet, poster, presentation template and infographics to present the project; the website is online

Project video

SCS will produce a video to communicate the global concept and objectives of the project distribute it to the partners and publish it via social platforms

Publicaciones

Peer reviewed articles (6)

Tuning the Immunostimulation Properties of Cationic Lipid Nanocarriers for Nucleic Acid Delivery

Autores: Arindam K. Dey, Adrien Nougarède, Flora Clément, Carole Fournier, Evelyne Jouvin-Marche, Marie Escudé, Dorothée Jary, Fabrice P. Navarro, Patrice N. Marche
Publicado en: Frontiers in Immunology, Edición 12, 2021, ISSN 1664-3224
Editor: Frontiers
DOI: 10.3389/fimmu.2021.722411

Therapeutic siRNAs targeting JAK/STAT signalling pathway in inflammatory bowel diseases

Autores: Flora Clément, Adrien Nougarède, Stéphanie Combe, Frédérique Kermarrec, Arindam K Dey, Patricia Obeid, Fabrice P Navarro, Patrice N Marche, Eric Sulpice, Xavier Gidrol
Publicado en: Journal of Crohn's and Colitis, 2021, ISSN 1873-9946
Editor: Elsevier Science
DOI: 10.1093/ecco-jcc/jjab129

Impact of Gold Nanoparticles on the Functions of Macrophages and Dendritic Cells

Autores: Arindam K. Dey, Alexis Gonon, Eve-Isabelle Pécheur, Mylène Pezet, Christian Villiers, Patrice N. Marche
Publicado en: Cells, Edición 10/1, 2021, Página(s) 96, ISSN 2073-4409
Editor: MDPI
DOI: 10.3390/cells10010096

Macro- and Microrheological Properties of Mucus Surrogates in Comparison to Native Intestinal and Pulmonary Mucus

Autores: Benedikt C. Huck, Olga Hartwig, Alexander Biehl, Konrad Schwarzkopf, Christian Wagner, Brigitta Loretz, Xabier Murgia, Claus-Michael Lehr
Publicado en: Biomacromolecules, Edición 20/9, 2019, Página(s) 3504-3512, ISSN 1525-7797
Editor: American Chemical Society
DOI: 10.1021/acs.biomac.9b00780

Surfactant-Free Glibenclamide Nanoparticles: Formulation, Characterization and Evaluation of Interactions with Biological Barriers

Autores: Eva C. Arrua, Olga Hartwig, Duy-Khiet Ho, Brigitta Loretz, Xabier Murgia, Claudio J. Salomon, Claus-Michael Lehr
Publicado en: Pharmaceutical Research, Edición 38/6, 2021, Página(s) 1081-1092, ISSN 0724-8741
Editor: Kluwer Academic/Plenum Publishers
DOI: 10.1007/s11095-021-03056-2

Synthesis and use of an amphiphilic dendrimer for siRNA delivery into primary immune cells

Autores: Jiaxuan Chen, Aleksandra Ellert-Miklaszewska, Stefano Garofalo, Arindam K. Dey, Jingjie Tang, Yifan Jiang, Flora Clément, Patrice N. Marche, Xiaoxuan Liu, Bozena Kaminska, Angela Santoni, Cristina Limatola, John J. Rossi, Jiehua Zhou, Ling Peng
Publicado en: Nature Protocols, Edición 16/1, 2021, Página(s) 327-351, ISSN 1754-2189
Editor: Nature Publishing Group
DOI: 10.1038/s41596-020-00418-9

Derechos de propiedad intelectual

Patent (1)

GASTROINTESTINAL TRACT SIMULATION SYSTEM, COMPARTMENTS THEREFOR, AND METHOD

Número de solicitud/publicación: 17 174613
Fecha: 2017-06-06
Solicitante(s): PRODIGEST