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The nanoparticle-scope : a new integrated instrument for accurate and reproducible physico-chemical characterisation of nanoparticles (npSCOPE)

Objective

The npSCOPE project aims at developing a new integrated instrument (the nanoparticle-scope) optimised for providing a complete physico-chemical characterisation of nanoparticles both in their pristine form or embedded in complex matrices such as biological tissues. Using sophisticated correlative data processing methodologies and algorithms based on statistical methods in conjunction with appropriate visualisation methods of the results, the npSCOPE instrument will allow rapid, accurate and reproducible measurements.
The instrument will be based on the Gas Field Ion Source as a key enabling technology, which we will combine with a number of new developments in the field of electron and ion microscopy. We will progressively ramp up the TRL of the instrument and associated methodologies to reach TRL 7 by the end of the project. The new technology, and all related processes and methodologies, will be validated via round-robin studies performed independently by several partner institutions, crosschecked with conventional analysis technologies to demonstrate the advancements and capabilities of the npSCOPE technology and benchmarked in representative case studies. Given the low sample quantities needed and the strong potential of the instrument to generate high-quality physico-chemical data on nanomaterials, both ex situ and in situ, npSCOPE will allow a major step forward in defining key descriptors for read-across, grouping, in silico modelling and creating meaningful relationships with biological activity data for QSAR purposes.
To reach these objectives, the project consortium will be composed of research centres internationally recognised for innovative instrument developments, well-established instrument manufacturers and experts in nanotoxicology in various fields of application to demonstrate and validate the applicability of npSCOPE for the risk assessment of nanomaterials in consumer products.

Field of science

  • /engineering and technology/environmental engineering/energy and fuels/fossil energy/gas
  • /natural sciences/computer and information sciences/data science/data processing
  • /engineering and technology/nanotechnology/nano-materials

Call for proposal

H2020-NMBP-2016-two-stage
See other projects for this call

Funding Scheme

RIA - Research and Innovation action

Coordinator

LUXEMBOURG INSTITUTE OF SCIENCE AND TECHNOLOGY
Address
5 Avenue Des Hauts Fourneaux
4362 Esch Sur Alzette
Luxembourg
Activity type
Research Organisations
EU contribution
€ 2 395 032,50

Participants (9)

CARL ZEISS MICROSCOPY GMBH
Germany
EU contribution
€ 1 200 000
Address
Carl Zeiss Promenade 10
07745 Jena
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
HELMHOLTZ-ZENTRUM DRESDEN-ROSSENDORF EV
Germany
EU contribution
€ 593 125
Address
Bautzner Landstrasse 400
01328 Dresden
Activity type
Research Organisations
PHOTONIS NETHERLANDS BV
Netherlands
EU contribution
€ 786 250
Address
Dwazziewegen 2
9301 ZR Roden
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
EIDGENOESSISCHE TECHNISCHE HOCHSCHULE ZUERICH
Switzerland
EU contribution
€ 0
Address
Raemistrasse 101
8092 Zuerich
Activity type
Higher or Secondary Education Establishments
FRIEDRICH-ALEXANDER-UNIVERSITAET ERLANGEN-NUERNBERG
Germany
EU contribution
€ 587 418,75
Address
Schlossplatz 4
91054 Erlangen
Activity type
Higher or Secondary Education Establishments
VLAAMSE INSTELLING VOOR TECHNOLOGISCH ONDERZOEK N.V.
Belgium
EU contribution
€ 447 925
Address
Boeretang 200
2400 Mol
Activity type
Research Organisations
MYBIOTECH GMBH
Germany
EU contribution
€ 202 000
Address
Industriestrasse 1B
66802 Uberherrn
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
MJR PHARMJET GMBH

Participation ended

Germany
EU contribution
€ 0
Address
Industriestrasse 1B
66802 Uberherrm
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
INSTITUT NATIONAL DE RECHERCHE POUR L'AGRICULTURE, L'ALIMENTATION ET L'ENVIRONNEMENT
France
EU contribution
€ 449 848,75
Address
Rue De L'universite 147
75338 Paris Cedex 07
Activity type
Research Organisations