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The nanoparticle-scope : a new integrated instrument for accurate and reproducible physico-chemical characterisation of nanoparticles (npSCOPE)

Objective

The npSCOPE project aims at developing a new integrated instrument (the nanoparticle-scope) optimised for providing a complete physico-chemical characterisation of nanoparticles both in their pristine form or embedded in complex matrices such as biological tissues. Using sophisticated correlative data processing methodologies and algorithms based on statistical methods in conjunction with appropriate visualisation methods of the results, the npSCOPE instrument will allow rapid, accurate and reproducible measurements.
The instrument will be based on the Gas Field Ion Source as a key enabling technology, which we will combine with a number of new developments in the field of electron and ion microscopy. We will progressively ramp up the TRL of the instrument and associated methodologies to reach TRL 7 by the end of the project. The new technology, and all related processes and methodologies, will be validated via round-robin studies performed independently by several partner institutions, crosschecked with conventional analysis technologies to demonstrate the advancements and capabilities of the npSCOPE technology and benchmarked in representative case studies. Given the low sample quantities needed and the strong potential of the instrument to generate high-quality physico-chemical data on nanomaterials, both ex situ and in situ, npSCOPE will allow a major step forward in defining key descriptors for read-across, grouping, in silico modelling and creating meaningful relationships with biological activity data for QSAR purposes.
To reach these objectives, the project consortium will be composed of research centres internationally recognised for innovative instrument developments, well-established instrument manufacturers and experts in nanotoxicology in various fields of application to demonstrate and validate the applicability of npSCOPE for the risk assessment of nanomaterials in consumer products.

Call for proposal

H2020-NMBP-2016-2017

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Sub call

H2020-NMBP-2016-two-stage

Coordinator

LUXEMBOURG INSTITUTE OF SCIENCE AND TECHNOLOGY
Net EU contribution
€ 2 395 032,50
Address
5 Avenue Des Hauts Fourneaux
4362 Esch Sur Alzette
Luxembourg

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Region
Luxembourg Luxembourg Luxembourg
Activity type
Research Organisations
Non-EU contribution
€ 0,00

Participants (9)

CARL ZEISS MICROSCOPY GMBH
Germany
Net EU contribution
€ 1 200 000,00
Address
Carl Zeiss Promenade 10
07745 Jena

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Region
Thüringen Thüringen Jena, Kreisfreie Stadt
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Non-EU contribution
€ 0,00
Third-party

Legal entity other than a subcontractor which is affiliated or legally linked to a participant. The entity carries out work under the conditions laid down in the Grant Agreement, supplies goods or provides services for the action, but did not sign the Grant Agreement. A third party abides by the rules applicable to its related participant under the Grant Agreement with regard to eligibility of costs and control of expenditure.

CARL ZEISS MICROSCOPY LLC
United States
Net EU contribution
€ 0,00
Address
One Zeiss Drive
10594 Thornwood

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Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Non-EU contribution
€ 81 250,00
HELMHOLTZ-ZENTRUM DRESDEN-ROSSENDORF EV
Germany
Net EU contribution
€ 593 125,00
Address
Bautzner Landstrasse 400
01328 Dresden

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Region
Sachsen Dresden Dresden, Kreisfreie Stadt
Activity type
Research Organisations
Non-EU contribution
€ 0,00
PHOTONIS NETHERLANDS BV
Netherlands
Net EU contribution
€ 786 250,00
Address
Dwazziewegen 2
9301 ZR Roden

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Region
Noord-Nederland Drenthe Noord-Drenthe
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Non-EU contribution
€ 0,00
EIDGENOESSISCHE TECHNISCHE HOCHSCHULE ZUERICH
Switzerland
Net EU contribution
€ 0,00
Address
Raemistrasse 101
8092 Zuerich

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Region
Schweiz/Suisse/Svizzera Zürich Zürich
Activity type
Higher or Secondary Education Establishments
Non-EU contribution
€ 744 625,00
FRIEDRICH-ALEXANDER-UNIVERSITAET ERLANGEN-NUERNBERG
Germany
Net EU contribution
€ 587 418,75
Address
Schlossplatz 4
91054 Erlangen

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Region
Bayern Mittelfranken Erlangen, Kreisfreie Stadt
Activity type
Higher or Secondary Education Establishments
Non-EU contribution
€ 0,00
VLAAMSE INSTELLING VOOR TECHNOLOGISCH ONDERZOEK N.V.
Belgium
Net EU contribution
€ 447 925,00
Address
Boeretang 200
2400 Mol

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Region
Vlaams Gewest Prov. Antwerpen Arr. Turnhout
Activity type
Research Organisations
Non-EU contribution
€ 0,00
MYBIOTECH GMBH
Germany
Net EU contribution
€ 202 000,00
Address
Industriestrasse 1B
66802 Uberherrn

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SME

The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.

Yes
Region
Saarland Saarland Saarlouis
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Non-EU contribution
€ 0,00
INSTITUT NATIONAL DE RECHERCHE POUR L'AGRICULTURE, L'ALIMENTATION ET L'ENVIRONNEMENT
France
Net EU contribution
€ 449 848,75
Address
147 Rue De L'universite
75007 Paris Cedex 07

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Region
Ile-de-France Ile-de-France Paris
Activity type
Research Organisations
Non-EU contribution
€ 0,00