Deliverables
Guide describing the preparation handling and storage of the nanomaterial samples
Evaluation report on performance of the npSCOPE instrument in representative test cases for risk assessmentPresentation and evaluation of npSCOPE results obtained in the nanotoxicology test cases including reproducibility based on the roundrobin studies and benchmarking against existing stateoftheart instruments
Description of correlative workflowA description of the sequence of measurements to be followed to ensure adequate characterisation both for nanotoxicology studies and other applications of the npSCOPE instrument
Evaluation report on performance of the npSCOPE instrument for applications beyond nanotoxicologyPresentation and evaluation of npSCOPE results obtained in test examples in materialsscience nanomedicine and pharmaceutics including reproducibility based on the roundrobin studies and benchmarking against existing stateoftheart instruments
List of validated performance specifications of the npSCOPE instrumentList of performance specifications of the instrument with details about samples and protocols used to determine the various parameters
Global validation report of npSCOPE instrument, including benchmarking against existing state-of-the-art techniquesReport describing the overall performance of the npSCOPE instrument and methodologies the application landscape and roadmaps for its future use
Confirmed specificationList of performance specifications for the npSCOPE instrument and its subsystems including mechanical and electrical interface definitions
Description of cryo-workflowA description of the sequence of measurements to be followed sample preparation and characterisation workflows to ensure adequate characterisation both for nanotoxicology studies and other applications of the npSCOPE instrument under cryoconditions
Website for the project is publically accessible with preliminary content
A final version of the data analysis software for the automated data processing and reporting within the npSCOPE project is delivered focusing on datasets from the npSCOPE instrument
Publications
Author(s):
Eduardo Serralta, Nico Klingner, Olivier De Castro, Michael Mousley, Santhana Eswara, Serge Duarte Pinto, Tom Wirtz, Gregor Hlawacek
Published in:
Beilstein Journal of Nanotechnology, Issue 11, 2020, Page(s) 1854-1864, ISSN 2190-4286
Publisher:
Beilstein-Institut Zur Forderung der Chemischen Wissenschaften
DOI:
10.3762/bjnano.11.167
Author(s):
Sebastian Primpke, Silke H. Christiansen, Win Cowger, Hannah De Frond, Ashok Deshpande, Marten Fischer, Erika B. Holland, Michaela Meyns, Bridget A. O'Donnell, Barbara E. Ossmann, Marco Pittroff, George Sarau, Barbara M. Scholz-Böttcher, Kara J. Wiggin
Published in:
Applied Spectroscopy, Issue 74/9, 2020, Page(s) 1012-1047, ISSN 0003-7028
Publisher:
Society for Applied Spectroscopy
DOI:
10.1177/0003702820921465
Author(s):
Silvan Kretschmer, Mikhail Maslov, Sadegh Ghaderzadeh, Mahdi Ghorbani-Asl, Gregor Hlawacek, Arkady V. Krasheninnikov
Published in:
ACS Applied Materials & Interfaces, Issue 10/36, 2018, Page(s) 30827-30836, ISSN 1944-8244
Publisher:
American Chemical Society
DOI:
10.1021/acsami.8b08471
Author(s):
Michael Mousley, Santhana Eswara, Olivier De Castro, Olivier Bouton, Nico Klingner, Christoph T Koch, Gregor Hlawacek, Tom Wirtz
Published in:
Beilstein Journal of Nanotechnology, Issue 10, 2019, Page(s) 1648-1657, ISSN 2190-4286
Publisher:
Beilstein-Institut Zur Forderung der Chemischen Wissenschaften
DOI:
10.3762/bjnano.10.160
Author(s):
Jean-Nicolas Audinot, Patrick Philipp, Olivier De Castro, Antje Biesemeier, Hung Quang Hoang, Tom Wirtz
Published in:
Reports on Progress in Physics, 2021, ISSN 0034-4885
Publisher:
Institute of Physics Publishing
DOI:
10.1088/1361-6633/ac1e32
Author(s):
Sadegh Ghaderzadeh, Vladimir Ladygin, Mahdi Ghorbani-Asl, Gregor Hlawacek, Marika Schleberger, Arkady V. Krasheninnikov
Published in:
ACS Applied Materials & Interfaces, Issue 12/33, 2020, Page(s) 37454-37463, ISSN 1944-8244
Publisher:
American Chemical Society
DOI:
10.1021/acsami.0c09255
Author(s):
Antje Biesemeier, Olivier De Castro, Eduardo Serralta, Jelena Lovric, Santhana Eswara, Jean-Nicolas Audinot, Sébastien Cambier, Tom Wirtz
Published in:
Microscopy and Microanalysis, Issue 26/S2, 2020, Page(s) 818-820, ISSN 1431-9276
Publisher:
Cambridge University Press
DOI:
10.1017/s1431927620015950
Author(s):
Win Cowger, Andrew Gray, Silke H. Christiansen, Hannah DeFrond, Ashok D. Deshpande, Ludovic Hemabessiere, Eunah Lee, Leonid Mill, Keenan Munno, Barbara E. Ossmann, Marco Pittroff, Chelsea Rochman, George Sarau, Shannon Tarby, Sebastian Primpke
Published in:
Applied Spectroscopy, Issue 74/9, 2020, Page(s) 989-1010, ISSN 0003-7028
Publisher:
Society for Applied Spectroscopy
DOI:
10.1177/0003702820929064
Author(s):
Tom Wirtz, Olivier De Castro, Antje Biesemeier, Hung Quang Hoang, Jean-Nicolas Audinot
Published in:
Microscopy and Microanalysis, Issue 26/S2, 2020, Page(s) 1972-1974, ISSN 1431-9276
Publisher:
Cambridge University Press
DOI:
10.1017/s1431927620019984
Author(s):
George Sarau, Lasse Kling, Barbara E. Oßmann, Ann-Katrin Unger, Frank Vogler, Silke H. Christiansen
Published in:
Applied Spectroscopy, Issue 74/9, 2020, Page(s) 1155-1160, ISSN 0003-7028
Publisher:
Society for Applied Spectroscopy
DOI:
10.1177/0003702820916250
Author(s):
Sadegh Ghaderzadeh, Mahdi Ghorbani-Asl, Silvan Kretschmer, Gregor Hlawacek, Arkady V Krasheninnikov
Published in:
Nanotechnology, Issue 31/3, 2020, Page(s) 035302, ISSN 0957-4484
Publisher:
Institute of Physics Publishing
DOI:
10.1088/1361-6528/ab4847
Author(s):
Tom Wirtz, Olivier De Castro, Antje Biesemeier, Hung Quang Hoang, Jean-Nicolas Audinot
Published in:
Microscopy and Microanalysis, Issue 26/S2, 2020, Page(s) 82-83, ISSN 1431-9276
Publisher:
Cambridge University Press
DOI:
10.1017/s143192762001332x
Author(s):
Tom Wirtz, Olivier De Castro, Jean-Nicolas Audinot, Patrick Philipp
Published in:
Annual Review of Analytical Chemistry, Issue 12/1, 2019, Page(s) 523-543, ISSN 1936-1327
Publisher:
Annual Reviews, Inc.
DOI:
10.1146/annurev-anchem-061318-115457
Author(s):
Ionel Fizeșan, Sébastien Cambier, Elisa Moschini, Aline Chary, Inge Nelissen, Johanna Ziebel, Jean-Nicolas Audinot, Tom Wirtz, Marcin Kruszewski, Anca Pop, Béla Kiss, Tommaso Serchi, Felicia Loghin, Arno C. Gutleb
Published in:
Particle and Fibre Toxicology, Issue 16/1, 2019, ISSN 1743-8977
Publisher:
BioMed Central
DOI:
10.1186/s12989-019-0297-1
Author(s):
Leonid Mill, David Wolff, Nele Gerrits, Patrick Philipp, Lasse Kling, Florian Vollnhals, Andrew Ignatenko, Christian Jaremenko, Yixing Huang, Olivier De Castro, Jean‐Nicolas Audinot, Inge Nelissen, Tom Wirtz, Andreas Maier, Silke Christiansen
Published in:
Small Methods, Issue 5/7, 2021, Page(s) 2100223, ISSN 2366-9608
Publisher:
Wiley-VCH GmbH
DOI:
10.1002/smtd.202100223
Author(s):
Jelena Lovric, Jean-Nicolas Audinot, Tom Wirtz
Published in:
Microscopy and Microanalysis, Issue 25/S2, 2019, Page(s) 1026-1027, ISSN 1431-9276
Publisher:
Cambridge University Press
DOI:
10.1017/s1431927619005865
Author(s):
M. Mousley, W. Möller, P. Philipp, G. Hlawacek, T. Wirtz, S. Eswara
Published in:
Scientific Reports, Issue 10/1, 2020, Page(s) 12058, ISSN 2045-2322
Publisher:
Nature Publishing Group
DOI:
10.1038/s41598-020-68955-7
Author(s):
Olivier De Castro, Antje Biesemeier, Eduardo Serralta, Nico Klingner, Gregor Hlawacek, Peter Gnauck, Serge Duarte Pinto, Falk Lucas, Cecilia Bebeacua, Tom Wirtz
Published in:
Microscopy and Microanalysis, Issue 26/S2, 2020, Page(s) 1976-1977, ISSN 1431-9276
Publisher:
Cambridge University Press
DOI:
10.1017/s1431927620019996
Author(s):
Janina Müller-Deile, George Sarau, Ahmed M. Kotb, Christian Jaremenko, Ulrike E. Rolle-Kampczyk, Christoph Daniel, Stefan Kalkhof, Silke H. Christiansen, Mario Schiffer
Published in:
Scientific Reports, Issue 11/1, 2021, Page(s) 1, ISSN 2045-2322
Publisher:
Nature Publishing Group
DOI:
10.1038/s41598-021-83883-w
Author(s):
Christine Coméra, Christel Cartier, Eric Gaultier, Olivier Catrice, Quentin Panouille, Sarah El Hamdi, Kristof Tirez, Inge Nelissen, Vassilia Théodorou, Eric Houdeau
Published in:
Particle and Fibre Toxicology, Issue 17/1, 2020, Page(s) 26, ISSN 1743-8977
Publisher:
BioMed Central
DOI:
10.1186/s12989-020-00357-z
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