Multimodal, Functional Bio-Photonic Imaging

Deliverables

Images of cells undergoing physiological changes with all imaging modalities
Two photon fluorescence, SHG and voltage recordings of mem-branes with different constituents
Compact broadband Ti:sapphire laser technology incorporating new pump sources

Compact broadband Ti:sapphire laser technology incorporating new pump sources, to be completed in collaboration with HighQ/DTU

Progress Report
Tissue classification technology based on OCT and its combination with US
Comprehensive Education Programme Report
Doctoral degree for 15 ESRs
Link between structural, metabolic and electrical activity and optical responses

Data (spectra, images or movies) that provides a link between structural, metabolic and electrical activity and optical responses

Mid Term report

The mid term review meeting may take place between month 18-26

Websites (external and internal for data sharing)

3 joint workshops (WS1, WS2, WS3, WS4)

4 joint workshops: (WS1, WS2, WS4) for 2 ECTS each and WS3 (bioethics) All workshops are joint efforts between TUE, MUW, and TUM

3 Summer Schools for 3 ECTS (SS1, SS2) and 5 ECTS (SS3)

Publications

Improving ultrasound images with elevational angular compounding based on acoustic refraction

Author(s): Parastoo Afshari, Christian Zakian, Vasilis Ntziachristos
Published in: Scientific Reports, Issue 10/1, 2020, ISSN 2045-2322
Publisher: Nature Publishing Group
DOI: 10.1038/s41598-020-75092-8

Mapping Electrochemical Heterogeneity at Gold Surfaces: A Second Harmonic Imaging Study

Author(s): Igor Nahalka; Gregor Zwaschka; R. Kramer Campen; Arianna Marchioro; Sylvie Roke
Published in: The Journal of Physical Chemistry C, Issue 124, 2020, ISSN 1932-7447
Publisher: American Chemical Society
DOI: 10.1021/acs.jpcc.0c02740

Measuring the sensitivity to optical feedback of single-frequency high-power laser diodes

Author(s): Mathias Christensen, Christof Zink, Muhammad Tahir Jamal, Anders Kragh Hansen, Ole Bjarlin Jensen, and Bernd Sumpf
Published in: Journal of the Optical Society of America B, Issue 38 (3), 2021, ISSN 0740-3224
Publisher: Optical Society of America
DOI: 10.1364/josab.417258

Diagnosis of Pituitary Adenoma Biopsies by Ultrahigh Resolution Optical Coherence Tomography Using Neuronal Networks

Author(s): Alexander Micko, Fabian Placzek, Roger Fonollà, Michael Winklehner, Ryan Sentosa, Arno Krause, Greisa Vila, Romana Höftberger, Marco Andreana, Wolfgang Drexler, Rainer A. Leitgeb, Angelika Unterhuber, Stefan Wolfsberger
Published in: Frontiers in Endocrinology, Issue 12, 2021, ISSN 1664-2392
Publisher: Frontiers Media
DOI: 10.3389/fendo.2021.730100

Depth resolved label-free multimodal optical imaging platform to study morpho-molecular composition of tissue

Author(s): Marco Andreana, Ryan Sentosa, Mikael T. Erkkilä, Wolfgang Drexler, Angelika Unterhuber
Published in: Photochemical & Photobiological Sciences, Issue 18/5, 2019, Page(s) 997-1008, ISSN 1474-905X
Publisher: Royal Society of Chemistry
DOI: 10.1039/c8pp00410b

Assessment of hessian-based Frangi vesselness filter in optoacoustic imaging

Author(s): Antonia Longo, Stefan Morscher, Jaber Malekzadeh Najafababdi, Dominik Jüstel, Christian Zakian, Vasilis Ntziachristos
Published in: Photoacoustics, Issue 20, 2020, Page(s) 100200, ISSN 2213-5979
Publisher: Elsevier GmbH
DOI: 10.1016/j.pacs.2020.100200

Morpho-molecular signal correlation between optical coherence tomography and Raman spectroscopy for superior image interpretation and clinical diagnosis

Author(s): Iwan W. Schie, Fabian Placzek, Florian Knorr, Eliana Cordero, Lara M. Wurster, Gregers G. Hermann, Karin Mogensen, Thomas Hasselager, Wolfgang Drexler, Jürgen Popp, Rainer A. Leitgeb
Published in: Scientific Reports, Issue 11/1, 2021, ISSN 2045-2322
Publisher: Nature Publishing Group
DOI: 10.1038/s41598-021-89188-2

Macroscopic fluorescence-lifetime imaging of NADH and protoporphyrin IX improves the detection and grading of 5-aminolevulinic acid-stained brain tumors

Author(s): Mikael T. Erkkilä, David Reichert, Johanna Gesperger, Barbara Kiesel, Thomas Roetzer, Petra A. Mercea, Wolfgang Drexler, Angelika Unterhuber, Rainer A. Leitgeb, Adelheid Woehrer, Angelika Rueck, Marco Andreana, Georg Widhalm
Published in: Scientific Reports, Issue 10/1, 2020, ISSN 2045-2322
Publisher: Nature Publishing Group
DOI: 10.1038/s41598-020-77268-8

Influence of pump beam shaping and noise on performance of a direct diode-pumped ultrafast Ti:sapphire laser

Author(s): Muhammad Tahir jamal, Anders Kragh Hansen, Mahmoud Tawfieq, Peter Eskil Andersen, Ole Bjarlin Jensen
Published in: Optics Express, Issue 28/21, 2020, Page(s) 31754, ISSN 1094-4087
Publisher: Optical Society of America
DOI: 10.1364/oe.404968

Continuous compensation of the phase mismatch by using temperature gradients for second harmonic generation

Author(s): Pierre-Marc Dansette; Maksim Eremchev; Andrejus Michailovas
Published in: Crossref, Issue 484 (1), 2021, ISSN 0030-4018
Publisher: Elsevier BV
DOI: 10.1016/j.optcom.2020.126687

Optical imaging of surface chemistry and dynamics in confinement

Author(s): Carlos Macias-Romero, Igor Nahalka, Halil I. Okur, Sylvie Roke
Published in: Science, Issue 357/6353, 2017, Page(s) 784-788, ISSN 0036-8075
Publisher: American Association for the Advancement of Science
DOI: 10.1126/science.aal4346

Interaction of Oil and Lipids in Freestanding Lipid Bilayer Membranes Studied with Label-Free High-Throughput Wide-Field Second-Harmonic Microscopy

Author(s): Orly B. Tarun, Maksim Yu Eremchev, Sylvie Roke
Published in: Langmuir, Issue 34/38, 2018, Page(s) 11305-11310, ISSN 0743-7463
Publisher: American Chemical Society
DOI: 10.1021/acs.langmuir.8b01790

Imaging of the human tympanic membrane by endoscopic optical coherence tomography

Author(s): Martin Schindler, Lars Kirsten, Joseph Morgenstern, Jonas Golde, Mikael Erkkilä, Julia Walther, Max Kemper, Matthias Bornitz, Marcus Neudert, Thomas Zahnert, Edmund Koch
Published in: Current Directions in Biomedical Engineering, Issue 4/1, 2018, Page(s) 305-308, ISSN 2364-5504
Publisher: De Gruyter
DOI: 10.1515/cdbme-2018-0074

Endoscopic optical coherence tomography with wide field-of-view for the morphological and functional assessment of the human tympanic membrane

Author(s): Lars Kirsten, Martin Schindler, Joseph Morgenstern, Mikael Timo Erkkilä, Jonas Golde, Julia Walther, Pascal Rottmann, Max Kemper, Matthias Bornitz, Marcus Neudert, Thomas Zahnert, Edmund Koch
Published in: Journal of Biomedical Optics, Issue 24/03, 2019, Page(s) 1, ISSN 1083-3668
Publisher: S P I E - International Society for Optical Engineering
DOI: 10.1117/1.JBO.24.3.031017

Combination of High-Resolution Optical Coherence Tomography and Raman Spectroscopy for Improved Staging and Grading in Bladder Cancer

Author(s): Daniela Bovenkamp, Ryan Sentosa, Elisabet Rank, Mikael Erkkilä, Fabian Placzek, Jeremias Püls, Wolfgang Drexler, Rainer Leitgeb, Nathalie Garstka, Shahrokh Shariat, Clara Stiebing, Iwan Schie, Jürgen Popp, Marco Andreana, Angelika Unterhuber
Published in: Applied Sciences, Issue 8/12, 2018, Page(s) 2371, ISSN 2076-3417
Publisher: MDPI AG
DOI: 10.3390/app8122371

Widefield fluorescence lifetime imaging of protoporphyrin IX for fluorescence-guided neurosurgery: an ex vivo feasibility study

Author(s): Mikael T. Erkkilä, Bianca Bauer, Nancy Hecker-Denschlag, Maria J. Madera Medina, Rainer A. Leitgeb, Angelika Unterhuber, Johanna Gesperger, Thomas Roetzer, Christoph Hauger, Wolfgang Drexler, Georg Widhalm, Marco Andreana
Published in: Journal of Biophotonics, 2019, ISSN 1864-063X
Publisher: Wiley - VCH Verlag GmbH & CO. KGaA
DOI: 10.1002/jbio.201800378

Coherent combining of high brightness tapered amplifiers for efficient non-linear conversion

Author(s): P. Albrodt, M. T. Jamal, A. K. Hansen, O. B. Jensen, G. Blume, K. Paschke, P. Crump, P. Georges, G. Lucas-Leclin
Published in: Optics Express, Issue 27/2, 2019, Page(s) 928, ISSN 1094-4087
Publisher: Optical Society of America
DOI: 10.1364/oe.27.000928

Endoscopic optical coherence tomography angiography using a forward imaging piezo scanner probe

Author(s): Lara M. Wurster, Ronak N. Shah, Fabian Placzek, Simon Kretschmer, Michael Niederleithner, Laurin Ginner, Jason Ensher, Michael P. Minneman, Erich E. Hoover, Hans Zappe, Wolfgang Drexler, Rainer A. Leitgeb, Çağlar Ataman
Published in: Journal of Biophotonics, Issue 2019-01-16, 2019, Page(s) e201800382, ISSN 1864-063X
Publisher: Wiley - VCH Verlag GmbH & CO. KGaA
DOI: 10.1002/jbio.201800382

Ensemble of Deep Convolutional Neural Networks for Classification of Early Barrett’s Neoplasia Using Volumetric Laser Endomicroscopy

Author(s): Roger Fonollà, Thom Scheeve, Maarten R. Struyvenberg, Wouter L. Curvers, Albert J. de Groof, Fons van der Sommen, Erik J. Schoon, Jacques J.G.H.M. Bergman, Peter H.N. de With
Published in: Applied Sciences, Issue 9/11, 2019, Page(s) 2183, ISSN 2076-3417
Publisher: MDPI
DOI: 10.3390/app9112183

Line Scan Raman Microspectroscopy for Label-Free Diagnosis of Human Pituitary Biopsies

Author(s): Daniela Bovenkamp, Alexander Micko, Jeremias Püls, Fabian Placzek, Romana Höftberger, Greisa Vila, Rainer Leitgeb, Wolfgang Drexler, Marco Andreana, Stefan Wolfsberger, Angelika Unterhuber
Published in: Molecules, Issue 24/19, 2019, Page(s) 3577, ISSN 1420-3049
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/molecules24193577

Spatiotemporal Imaging of Water in Operating Voltage-Gated Ion Channels Reveals the Slow Motion of Interfacial Ions

Author(s): Orly B. Tarun, Maksim Yu. Eremchev, Aleksandra Radenovic, Sylvie Roke
Published in: Nano Letters, 2019, ISSN 1530-6984
Publisher: American Chemical Society
DOI: 10.1021/acs.nanolett.9b02024

En face optical coherence tomography: a technology review [Invited]

Author(s): R. A. Leitgeb
Published in: Biomedical Optics Express, Issue 10/5, 2019, Page(s) 2177, ISSN 2156-7085
Publisher: The Optical Society
DOI: 10.1364/BOE.10.002177

Capsule optoacoustic endoscopy for esophageal imaging

Author(s): Hailong He, Antonios Stylogiannis, Parastoo Afshari, Tobias Wiedemann, Katja Steiger, Andreas Buehler, Christian Zakian, Vasilis Ntziachristos
Published in: Journal of Biophotonics, Issue 12/10, 2019, ISSN 1864-063X
Publisher: Wiley - VCH Verlag GmbH & CO. KGaA
DOI: 10.1002/jbio.201800439

Peculiarities of second harmonic generation with chirped femtosecond pulses at high conversion efficiency

Author(s): Pierre-Marc Dansette, Raimundas Burokas, Laurynas Veselis, Audrius Zaukevičius, Andrejus Michailovas, Nerijus Rusteika
Published in: Optics Communications, Issue 455, 2020, Page(s) 124462, ISSN 0030-4018
Publisher: Elsevier BV
DOI: 10.1016/j.optcom.2019.124462

Morpho-molecular ex vivo detection and grading of non-muscle-invasive bladder cancer using forward imaging probe based multimodal optical coherence tomography and Raman spectroscopy

Author(s): Fabian Placzek, Eliana Cordero Bautista, Simon Kretschmer, Lara M. Wurster, Florian Knorr, Gerardo González-Cerdas, Mikael T. Erkkilä, Patrick Stein, Çağlar Ataman, Gregers G. Hermann, Karin Mogensen, Thomas Hasselager, Peter E. Andersen, Hans Zappe, Jürgen Popp, Wolfgang Drexler, Rainer A. Leitgeb, Iwan W. Schie
Published in: The Analyst, 2020, ISSN 0003-2654
Publisher: Royal Society of Chemistry
DOI: 10.1039/c9an01911a

Surgical microscope with integrated fluorescence lifetime imaging for 5-aminolevulinic acid fluorescence-guided neurosurgery

Author(s): Mikael T. Erkkilä, David Reichert, Nancy Hecker-Denschlag, Marco Wilzbach, Christoph Hauger, Rainer A. Leitgeb, Johanna Gesperger, Barbara Kiesel, Thomas Roetzer, Georg Widhalm, Wolfgang Drexler, Angelika Unterhuber, Marco Andreana
Published in: Journal of Biomedical Optics, Issue 25/07, 2020, Page(s) 1, ISSN 1083-3668
Publisher: S P I E - International Society for Optical Engineering
DOI: 10.1117/1.jbo.25.7.071202

Towards real-time wide-field fluorescence lifetime imaging of 5-ALA labeled brain tumors with multi-tap CMOS cameras

Author(s): David Reichert, Mikael T. Erkkilä, Gerhard Holst, Nancy Hecker-Denschlag, Marco Wilzbach, Christoph Hauger, Wolfgang Drexler, Johanna Gesperger, Barbara Kiesel, Thomas Roetzer, Angelika Unterhuber, Georg Widhalm, Rainer A. Leitgeb, Marco Andreana
Published in: Biomedical Optics Express, Issue 11/3, 2020, Page(s) 1598, ISSN 2156-7085
Publisher: The Optical Society
DOI: 10.1364/boe.382817

Selecting optimal spectral bands for improved detection of autofluorescent biomarkers in multiphoton microscopy

Author(s): Björn-Ole Meyer, M. Pilar J. Stella, Bjørn Holst, Boye S. Nielsen, Kim Holmstrøm, Peter E. Andersen, Dominik Marti
Published in: Journal of Biomedical Optics, Issue 25/07, 2020, Page(s) 1, ISSN 1083-3668
Publisher: S P I E - International Society for Optical Engineering
DOI: 10.1117/1.jbo.25.7.071206

Fusion of augmented reality imaging with the endoscopic view for endonasal skull base surgery; a novel application for surgical navigation based on intraoperative cone beam computed tomography and optical tracking

Author(s): Marco Lai, Simon Skyrman, Caifeng Shan, Drazenko Babic, Robert Homan, Erik Edström, Oscar Persson, Gustav Burström, Adrian Elmi-Terander, Benno H. W. Hendriks, Peter H. N. de With
Published in: PLOS ONE, Issue 15/1, 2020, Page(s) e0227312, ISSN 1932-6203
Publisher: Public Library of Science
DOI: 10.1371/journal.pone.0227312

Imaging the Heterogeneity of the Oxygen Evolution Reaction on Gold Electrodes Operando: Activity is Highly Local

Author(s): Gregor Zwaschka, Igor Nahalka, Arianna Marchioro, Yujin Tong, Sylvie Roke, R. Kramer Campen
Published in: ACS Catalysis, Issue 10/11, 2020, Page(s) 6084-6093, ISSN 2155-5435
Publisher: American Chemical Society
DOI: 10.1021/acscatal.0c01177

A CNN CADx System for Multimodal Classification of Colorectal Polyps Combining WL, BLI, and LCI Modalities

Author(s): Roger Fonollà, Quirine E. W. van der Zander, Ramon M. Schreuder, Ad A. M. Masclee, Erik J. Schoon, Fons van der Sommen, Peter H. N. de With
Published in: Applied Sciences, Issue 10/15, 2020, Page(s) 5040, ISSN 2076-3417
Publisher: MDPI
DOI: 10.3390/app10155040

Comparison of optical coherence tomography angiography and narrow-band imaging using a bimodal endoscope

Author(s): Lara M. Wurster, Simon Kretschmer, Jan Jäger, Fabian Placzek, Laurin Ginner, Wolfgang Drexler, Çağlar Ataman, Rainer A. Leitgeb, Hans Zappe
Published in: Journal of Biomedical Optics, Issue 25/03, 2020, Page(s) 1, ISSN 1083-3668
Publisher: S P I E - International Society for Optical Engineering
DOI: 10.1117/1.jbo.25.3.032003

Towards ultrahigh resolution OCT based endoscopical pituitary gland and adenoma screening: a performance parameter evaluation

Author(s): Fabian Placzek, Alexander Micko, Ryan Sentosa, Roger Fonollà, Michael Winklehner, Arthur Hosmann, Marco Andreana, Romana Höftberger, Wolfgang Drexler, Rainer A. Leitgeb, Stefan Wolfsberger, Angelika Unterhuber
Published in: Biomedical Optics Express, Issue 11/12, 2020, Page(s) 7003, ISSN 2156-7085
Publisher: The Optical Society
DOI: 10.1364/BOE.409987

Automatic image and text-based description for colorectal polyps using BASIC classification

Author(s): Roger Fonollà, Quirine E.W. van der Zander, Ramon M. Schreuder, Sharmila Subramaniam, Pradeep Bhandari, Ad A.M. Masclee, Erik J. Schoon, Fons van der Sommen, Peter H.N. de With
Published in: Artificial Intelligence in Medicine, Issue 121, 2021, Page(s) 102178, ISSN 0933-3657
Publisher: Elsevier BV
DOI: 10.1016/j.artmed.2021.102178

Practical, open source, GPU-accelerated, high-fidelity phase retrieval by simultaneous propagations

Author(s): Muhammad Tahir Jamal, Anders Kragh Hansen
Published in: Applied Optics, Issue 59/34, 2020, Page(s) 10761, ISSN 1559-128X
Publisher: The Optical Society
DOI: 10.1364/ao.402859

Ultrashort pulse Kagome hollow-core photonic crystal fiber delivery for nonlinear optical imaging

Author(s): Marco Andreana, Tuan Le, Wolfgang Drexler, Angelika Unterhuber
Published in: Optics Letters, Issue 44/7, 2019, Page(s) 1588, ISSN 0146-9592
Publisher: Optical Society of America
DOI: 10.1364/ol.44.001588

Ultra-broadband axicon transducer for optoacoustic endoscopy

Author(s): Zakiullah Ali, Christian Zakian, Vasilis Ntziachristos
Published in: Scientific Reports, Issue 11, 2021, Page(s) 1654, ISSN 2045-2322
Publisher: Nature Publishing Group
DOI: 10.1038/s41598-021-81117-7

Enhanced medical diagnosis for dOCTors: a perspective of optical coherence tomography

Author(s): Rainer Leitgeb, Fabian Placzek, Elisabet Rank, Lisa Krainz, Richard Haindl, Qian Li, Mengyang Liu, Marco Andreana, Angelika Unterhuber, Tilman Schmoll, Wolfgang Drexler
Published in: Journal of Biomedical Optics, Issue 26/10, 2021, ISSN 1083-3668
Publisher: S P I E - International Society for Optical Engineering
DOI: 10.1117/1.jbo.26.10.100601

Development of a CT-compatible anthropomorphic skull phantom for surgical planning, training, and simulation

Author(s): Lai, Marco Skyrman, Simon Kor, Flip Homan, Robert Babic, Drazenko Edström, Erik Persson, Oscar Burström, Gustav Elmi-Terander, Adrian Hendriks, Benno H. W. de With, Peter H. N.
Published in: Medical Imaging 2021: Imaging Informatics for Healthcare, Research, and Applications, 2021
Publisher: SPIE
DOI: 10.1117/12.2577629

Evaluation of a non-contact Photo-Plethysmographic Imaging (iPPG) system for peripheral arterial disease assessment

Author(s): Marco Lai, Claudio Spiridione Dicorato, Marco de Wild, Frank Verbakel, Sergei Shulepov, Joanneke Groen, Marc Notten, Gerald Lucassen, Marc R. H. M. van Sambeek, Benno H. W. Hendriks, Peter H. N. de With
Published in: Medical Imaging 2021: Biomedical Applications in Molecular, Structural, and Functional Imaging, 2021, Page(s) 12, ISBN 9781510640306
Publisher: SPIE
DOI: 10.1117/12.2580640

Feasibility of Colonic Polyp classification with CNN based on Blue Light and Linked Color Imaging

Author(s): Fonollà, Roger van der Sommen, Fons Schreuder, R.M. Schoon, E.J. de With, P.H.N.
Published in: Symposium on information theory and signal processing in the benelux, Issue 39, 2018, Page(s) 85, ISBN 978-90-365-4570-9
Publisher: University of Twente

Polyp malignancy classification with CNN features based on Blue Laser and Linked Color Imaging

Author(s): Roger Fonolla Navarro, Fons Van Der Sommen, Peter H N De With, Ramon M Schreuder, Erik J Schoon
Published in: Proceedings of NCCV2018, 2018
Publisher: NCCV

Hand-Eye Camera Calibration with an Optical Tracking System

Author(s): Marco Lai, Caifeng Shan, Peter H.N. de With
Published in: Proceedings of the 12th International Conference on Distributed Smart Cameras - ICDSC '18, 2018, Page(s) 1-6, ISBN 9781-450365116
Publisher: ACM Press
DOI: 10.1145/3243394.3243700

Image fusion on the endoscopic view for endo-nasal skull-base surgery

Author(s): Marco Lai, Caifeng Shan, Drazenko Babic, Robert Homan, Adrian Elmi Terander, Erik Edstrom, Oscar Persson, Gustav Burstrom, Peter H. N. de With
Published in: Medical Imaging 2019: Image-Guided Procedures, Robotic Interventions, and Modeling, 2019, Page(s) 48, ISBN 9781-510625501
Publisher: SPIE
DOI: 10.1117/12.2512734

Tuning of an integrated tunable laser for swept source optical coherence tomography Tuning of an Integrated Tunable Laser for Swept Source Optical Coherence Tomography

Author(s): Rastko Pajković, Kevin Williams, Erwin Bente
Published in: Tuning of an integrated tunable laser for swept source optical coherence tomography, 2017, Page(s) 164-167
Publisher: IEEE Benelux Chapter

Multi-Modal Classification of Polyp Malignancy using CNN Features with Balanced Class Augmentation

Author(s): Roger Fonolla, Fons van der Sommen, Ramon M. Schreuder, Erik J. Schoon, Peter H.N. de With
Published in: 2019 IEEE 16th International Symposium on Biomedical Imaging (ISBI 2019), 2019, Page(s) 74-78, ISBN 978-1-5386-3641-1
Publisher: IEEE
DOI: 10.1109/isbi.2019.8759320

Dynamic properties of wavelength switching in a widely tunable semiconductor laser for optical coherence tomography

Author(s): Rastko Pajkovic, Daniel Garbi, Kevin Williams, Erwin Bente
Published in: Semiconductor Lasers and Laser Dynamics IX, Issue 2020, 2020, Page(s) 19, ISBN 9781-510634855
Publisher: SPIE
DOI: 10.1117/12.2555620

Automated classification of brain tissue: comparison between hyperspectral imaging and diffuse reflectance spectroscopy

Author(s): Marco Lai, Simon Skyrman, Caifeng Shan, Elvira Paulussen, Francesca Manni, Akash Swamy, Drazenko Babic, Erik Edström, Oscar Persson, Gustav Burström, Adrian Elmi Terander, Benno H. W. Hendriks, Peter H. N. de With
Published in: Medical Imaging 2020: Image-Guided Procedures, Robotic Interventions, and Modeling, Issue 2020, 2020, Page(s) 62, ISBN 9781-510633988
Publisher: SPIE
DOI: 10.1117/12.2548754

Triplet network for classification of benign and pre-malignant polyps

Author(s): Roger Fonollà, Maciej Smyl, Fons van der Sommen, Ramon-Michel Schreuder, Erik J. Schoon, Peter H. N. de With
Published in: Medical Imaging 2021: Computer-Aided Diagnosis, 2021, Page(s) 107, ISBN 9781510640245
Publisher: SPIE
DOI: 10.1117/12.2577546

Doppler optical coherence tomography as a promising tool for detecting fluid in the human middle ear

Author(s): Lars Kirsten, Simon Baumgärtner, Mikael Timo Erkkilä, Jonas Golde, Max Kemper, Thomas Stoppe, Matthias Bornitz, Marcus Neudert, Thomas Zahnert, Edmund Koch
Published in: Current Directions in Biomedical Engineering, Issue 2/1, 2016, ISSN 2364-5504
Publisher: De Gruyter
DOI: 10.1515/cdbme-2016-0098

Functional and morphological imaging of the human tympanic membrane with endoscopic optical coherence tomography

Author(s): Lars Kirsten, Joseph Morgenstern, Mikael Timo Erkkilä, Martin Schindler, Jonas Golde, Julia Walther, Max Kemper, Thomas Stoppe, Matthias Bornitz, Marcus Neudert, Thomas Zahnert, Edmund Koch
Published in: Current Directions in Biomedical Engineering, Issue 3/2, 2017, ISSN 2364-5504
Publisher: De Gruyter
DOI: 10.1515/cdbme-2017-0021

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