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Single Molecule Nanoscale Sensors for Improved Therapies and Diagnostics

Objective

One of the most significant challenges facing the healthcare community is the accurate and selective detection and quantification of trace levels of analyte. This can have enormous impact with numerous application, especially in the context of biosensing, where applications can range from early stage detection of disease to the identification of new markers amongst others. These challenges are compounded when the analysis of real samples or even complex mixtures are required. To address this need, single molecule or near single molecule methods are currently being heavily pursued which allows for the discrimination of events with low copy numbers by removing the “clouding” associated with ensemble averaging. Although strategies for detecting single molecules have existed for a number of years, efficient and cost-effective label-free methods without the need for chemical modification are lacking especially when considering smaller molecules directly in unprocessed clinical samples. As part of this proposal, I intend to address this limitation by developing new strategies in single molecule nanoscale sensing which will be both highly sensitive and selective for improved therapeutics and diagnostics applications.

Fields of science (EuroSciVoc)

CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.

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Keywords

Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)

Programme(s)

Multi-annual funding programmes that define the EU’s priorities for research and innovation.

Topic(s)

Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.

Funding Scheme

Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.

ERC-COG - Consolidator Grant

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Call for proposal

Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.

(opens in new window) ERC-2016-COG

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Host institution

IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE
Net EU contribution

Net EU financial contribution. The sum of money that the participant receives, deducted by the EU contribution to its linked third party. It considers the distribution of the EU financial contribution between direct beneficiaries of the project and other types of participants, like third-party participants.

€ 1 997 680,00
Address
SOUTH KENSINGTON CAMPUS EXHIBITION ROAD
SW7 2AZ London
United Kingdom

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Region
London Inner London — West Westminster
Activity type
Higher or Secondary Education Establishments
Links
Total cost

The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.

€ 1 997 680,00

Beneficiaries (1)

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