Collective Infectious Units and the Social Evolution of Viruses

Project Information

Vis-a-Vis

Grant agreement ID: 724519

DOI 10.3030/724519

Project closed

EC signature date 12 April 2017

Start date 1 May 2017

End date 30 April 2022

Funded under

• EXCELLENT SCIENCE - European Research Council (ERC)

Total cost € 1 969 821,00

EU contribution € 1 969 821,00

Coordinated by

UNIVERSITAT DE VALENCIA
Spain

Publications

Peer reviewed articles (24)

Isolation and Characterization of Two Klebsiella pneumoniae Phages Encoding Divergent Depolymerases

Author(s): Pilar Domingo-Calap; Beatriz Beamud; Lucas Mora-Quilis; Fernando González-Candelas; Rafael Sanjuán
Published in: International Journal of Molecular Sciences, Vol 21, Iss 3160, p 3160 (2020), Issue 1, 2020, ISSN 1422-0067
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms21093160

Fibrinogen Gamma Chain Promotes Aggregation of Vesicular Stomatitis Virus in Saliva.

Author(s): Valesca Anschau; Rafael Sanjuán
Published in: Viruses, Vol 12, Iss 3, p 282 (2020), Issue 1, 2020, ISSN 1999-4915
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/v12030282

Social Bacteriophages

Author(s): Pilar Domingo-Calap; Rafael Sanjuan; LUCAS MORA QUILIS
Published in: Microorganisms, Vol 8, Iss 533, p 533 (2020), Issue 1, 2020, ISSN 2076-2607
Publisher: MDPI
DOI: 10.3390/microorganisms8040533

Five challenges in the field of viral diversity and evolution

Author(s): Rafael Sanjuán, Christopher JR Illingworth, Jemma L Geoghegan, Jaime Iranzo, Mark P Zwart, Alexander T Ciota, Gonzalo Moratorio, Selma Gago-Zachert, Siobain Duffy, Dhanasekaran Vijaykrishna
Published in: Frontiers in Virology, 2021, ISSN 2673-818X
Publisher: Frontiers Media SA
DOI: 10.3389/fviro.2021.684949

The Social Life of Viruses

Author(s): Rafael Sanjuán
Published in: Annual Review of Virology, 2021, ISSN 2327-0578
Publisher: Annual Reviews
DOI: 10.1146/annurev-virology-091919-071712

Collective Viral Spread Mediated by Virion Aggregates Promotes the Evolution of Defective Interfering Particles.

Author(s): Iván Andreu-Moreno; Rafael Sanjuán
Published in: mBio, Vol 11, Iss 1, p e02156-19 (2020), Issue 1, 2020, ISSN 2150-7511
Publisher: American Society for Microbiology (ASM)
DOI: 10.1128/mbio.02156-19

Collective Infection of Cells by Viral Aggregates Promotes Early Viral Proliferation and Reveals a Cellular-Level Allee Effect

Author(s): Iván Andreu-Moreno, Rafael Sanjuán
Published in: Current Biology, Issue 28/20, 2018, Page(s) 3212-3219.e4, ISSN 0960-9822
Publisher: Cell Press
DOI: 10.1016/j.cub.2018.08.028

Sociovirology: Conflict, Cooperation, and Communication among Viruses

Author(s): Samuel L. Díaz-Muñoz, Rafael Sanjuán, Stuart West
Published in: Cell Host & Microbe, Issue 22/4, 2017, Page(s) 437-441, ISSN 1931-3128
Publisher: Cell Press
DOI: 10.1016/j.chom.2017.09.012

Collective properties of viral infectivity

Author(s): Rafael Sanjuán
Published in: Current Opinion in Virology, Issue 33, 2018, Page(s) 1-6, ISSN 1879-6257
Publisher: Elsevier BV
DOI: 10.1016/j.coviro.2018.06.001

Beneficial coinfection can promote within-host viral diversity

Author(s): Asher Leeks, Ernesto A Segredo-Otero, Rafael Sanjuán, Stuart A West
Published in: Virus Evolution, Issue 4/2, 2018, ISSN 2057-1577
Publisher: Oxford University Press
DOI: 10.1093/ve/vey028

Collective Infectious Units in Viruses

Author(s): Rafael Sanjuán
Published in: Trends in Microbiology, Issue 25/5, 2017, Page(s) 402-412, ISSN 0966-842X
Publisher: Elsevier BV
DOI: 10.1016/j.tim.2017.02.003

Multi-virion infectious units arise from free viral particles in an enveloped virus

Author(s): José M. Cuevas, María Durán-Moreno, Rafael Sanjuán
Published in: Nature Microbiology, Issue 2, 2017, Page(s) 17078, ISSN 2058-5276
Publisher: Nature Microbiology
DOI: 10.1038/nmicrobiol.2017.78

Genome-scale analysis of evolutionary rate and selection in a fast-expanding Spanish cluster of HIV-1 subtype F1

Author(s): Juan Á. Patiño-Galindo, Francisco Domínguez, María T. Cuevas, Elena Delgado, Mónica Sánchez, Lucía Pérez-Álvarez, Michael M. Thomson, Rafael Sanjuán, Fernando González-Candelas, José M. Cuevas
Published in: Infection, Genetics and Evolution, Issue 66, 2018, Page(s) 43-47, ISSN 1567-1348
Publisher: Elsevier BV
DOI: 10.1016/j.meegid.2018.09.008

Social evolution of innate immunity evasion in a virus

Author(s): Pilar Domingo-Calap, Ernesto Segredo-Otero, María Durán-Moreno, Rafael Sanjuán
Published in: Nature Microbiology, Issue 4/6, 2019, Page(s) 1006-1013, ISSN 2058-5276
Publisher: Nature Publishing Group
DOI: 10.1038/s41564-019-0379-8

Directed Evolution of a Mycobacteriophage

Author(s): Cebriá-Mendoza, Sanjuán, Domingo-Calap
Published in: Antibiotics, Issue 8/2, 2019, Page(s) 46, ISSN 2079-6382
Publisher: MDPI
DOI: 10.3390/antibiotics8020046

The effect of genetic complementation on the fitness and diversity of viruses spreading as collective infectious units

Author(s): Ernesto Segredo-Otero, Rafael Sanjuán
Published in: Virus Research, Issue 267, 2019, Page(s) 41-48, ISSN 0168-1702
Publisher: Elsevier BV
DOI: 10.1016/j.virusres.2019.05.005

Membrane-Associated Enteroviruses Undergo Intercellular Transmission as Pools of Sibling Viral Genomes

Author(s): Juan-Vicente Bou, Ron Geller, Rafael Sanjuán
Published in: Cell Reports, Issue 29/3, 2019, Page(s) 714-723.e4, ISSN 2211-1247
Publisher: Cell Press
DOI: 10.1016/j.celrep.2019.09.014

Why viruses sometimes disperse in groups†

Author(s): Rafael Sanjuán, María-Isabel Thoulouze
Published in: Virus Evolution, Issue 5/1, 2019, ISSN 2057-1577
Publisher: Oxford University Press
DOI: 10.1093/ve/vez014

The evolution of collective infectious units in viruses

Author(s): Asher Leeks, Rafael Sanjuán, Stuart A. West
Published in: Virus Research, Issue 265, 2019, Page(s) 94-101, ISSN 0168-1702
Publisher: Elsevier BV
DOI: 10.1016/j.virusres.2019.03.013

Improvement of baculovirus as protein expression vector and as biopesticide by CRISPR/Cas9 editing

Author(s): Pazmiño‐Ibarra, Verónica; Mengual‐Martí, Adrià; Targovnik, Alexandra Marisa; Herrero, Salvador
Published in: Biotechnology and Bioengineering, 2019, Page(s) 2823–2833, ISSN 1097-0290
Publisher: Wiley
DOI: 10.1002/bit.27139

Experimental Evolution Reveals a Genetic Basis for Membrane-Associated Virus Release.

Author(s): Juan-Vicente Bou; Rafael Sanjuán
Published in: Molecular Biology and Evolution, Issue 2, 2021, ISSN 0737-4038
Publisher: Oxford University Press
DOI: 10.1093/molbev/msaa208

Isolation of Four Lytic Phages Infecting Klebsiella pneumoniae K22 Clinical Isolates from Spain

Author(s): Pilar Domingo-Calap; Beatriz Beamud; Justine Vienne; Fernando González-Candelas; Rafael Sanjuán
Published in: International Journal of Molecular Sciences, Issue 7, 2020, ISSN 1422-0067
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms21020425

Cooperative nature of viral replication

Author(s): Iván Andreu-Moreno; Juan-Vicente Bou; Rafael Sanjuán
Published in: Science Advances, Issue 1, 2020, ISSN 2375-2548
Publisher: American Association for the Advancement of Science's (AAAS)
DOI: 10.1126/sciadv.abd4942

The role of spatial structure in the evolution of viral innate immunity evasion: A diffusion-reaction cellular automaton model.

Author(s): Ernesto Segredo-Otero; Rafael Sanjuán
Published in: PLoS Computational Biology, Vol 16, Iss 2, p e1007656 (2020), Issue 1, 2020, ISSN 1553-7358
Publisher: PloS
DOI: 10.1371/journal.pcbi.1007656