Smart Lab-On-Chips for the Real -Time Control of Cells

Project Information

SmartCells

Grant agreement ID: 724813

DOI 10.3030/724813

Project closed

EC signature date 21 March 2017

Start date 1 April 2017

End date 30 September 2023

Funded under

• EXCELLENT SCIENCE - European Research Council (ERC)

Total cost € 2 198 150,99

EU contribution € 2 198 150,99

Coordinated by

CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS
France

Deliverables

Open Research Data Pilot (3)

Data Management Plan (V1)

First version of the DMP

Data Management Plan (V2)

Mid-term review of the DMP

Data Management Plan (V3)

Final review of the DMP

Publications

Peer reviewed articles (11)

Optogenetic spatial patterning of cooperation in yeast populations

Author(s): Matthias Le Bec, Sylvain Pouzet, Céline Cordier, Simon Barral, Vittore Scolari, Benoit Sorre, Alvaro Banderas, Pascal Hersen
Published in: Nature Communications, 2024, ISSN 2041-1723
Publisher: Nature Publishing Group
DOI: 10.1038/s41467-023-44379-5

Rational programming of history-dependent logic in cellular populations

Author(s): Ana Zúñiga, Sarah Guiziou, Pauline Mayonove, Zachary Ben Meriem, Miguel Camacho, Violaine Moreau, Luca Ciandrini, Pascal Hersen, Jerome Bonnet
Published in: Nature Communications, 2020, ISSN 2041-1723
Publisher: Nature Publishing Group
DOI: 10.1038/s41467-020-18455-z

"Observing Nutrient Gradients, Gene Expression and Growth Variation Using the ""Yeast Machine"" Microfluidic Device"

Author(s): Marinkovic, Zoran; Vulin, Clément; Acman, Mislav; Song, Xiaohu; Di Meglio, Jean; Lindner, Ariel; Hersen, Pascal
Published in: Bio-protocol, Issue 1, 2020, ISSN 2331-8325
Publisher: Bio-protocol LLC
DOI: 10.21769/bioprotoc.3668

Yeast cell responses and survival during periodic osmotic stress are controlled by glucose availability

Author(s): Fabien Duveau, Céline Cordier, Lionel Chiron, Matthias LeBec, Sylvain Pouzet, Julie Séguin, Artémis Llamosi, B. Sorre, Jean-Marc Di Meglio, Pascal Hersen
Published in: eLife, 2023, ISSN 2050-084X
Publisher: eLife Sciences Publications
DOI: 10.7554/elife.88750.1

The Promise of Optogenetics for Bioproduction: Dynamic Control Strategies and Scale-Up Instruments.

Author(s): Sylvain Pouzet; Sylvain Pouzet; Sylvain Pouzet; Alvaro Banderas; Alvaro Banderas; Alvaro Banderas; Matthias Le Bec; Matthias Le Bec; Matthias Le Bec; Thomas Lautier; Thomas Lautier; Gilles Truan; Pascal Hersen; Pascal Hersen; Pascal Hersen
Published in: Bioengineering, 2020, ISSN 2306-5354
Publisher: MDPI
DOI: 10.3390/bioengineering7040151

Balancing a genetic toggle switch by real-time feedback control and periodic forcing

Author(s): Jean-Baptiste Lugagne, Sebastián Sosa Carrillo, Melanie Kirch, Agnes Köhler, Gregory Batt, Pascal Hersen
Published in: Nature Communications, Issue 8/1, 2017, ISSN 2041-1723
Publisher: Nature Publishing Group
DOI: 10.1038/s41467-017-01498-0

Identification of individual cells from z-stacks of bright-field microscopy images

Author(s): Lugagne, Jean-Baptiste; Jain, Srajan; Ivanovitch, Pierre; Ben Meriem, Zacchary; Vulin, Clément; Fracassi, Chiara; Batt, Gregory; Hersen, Pascal
Published in: Scientific Reports, Issue 1, 2018, ISSN 2045-2322
Publisher: Nature Publishing Group
DOI: 10.3929/ethz-b-000280906

Hyperosmotic Stress Response Memory is Modulated by Gene Positioning in Yeast

Author(s): Zacchari Ben Meriem, Yasmine Khalil, Pascal Hersen, Emmanuelle Fabre
Published in: Cells, Issue 8/6, 2019, Page(s) 582, ISSN 2073-4409
Publisher: MDPI
DOI: 10.3390/cells8060582

A microfluidic device for inferring metabolic landscapes in yeast monolayer colonies

Author(s): Zoran S Marinkovic, Clément Vulin, Mislav Acman, Xiaohu Song, Jean-Marc Di Meglio, Ariel B Lindner, Pascal Hersen
Published in: eLife, Issue 8, 2019, ISSN 2050-084X
Publisher: eLife Sciences Publications
DOI: 10.7554/elife.47951

Autonomous and Assisted Control for Synthetic Microbiology.

Author(s): Banderas, Alvaro; Le Bec, Matthias; Cordier, Céline; Hersen, Pascal
Published in: International Journal of Molecular Sciences, 2020, 21 (23), pp.9223., Issue 4, 2020, Page(s) Basel, Switzerland, ISSN 1422-0067
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms21239223

CyberSco.Py an open-source software for event-based, conditional microscopy.

Author(s): Lionel Chiron, Matthias Le Bec, Céline Cordier, Sylvain Pouzet, Dimitrije Milunov, Alvaro Banderas, Jean-Marc Di Meglio, Benoit Sorre, Pascal Hersen
Published in: Scientific Reports, 2022, ISSN 2045-2322
Publisher: Nature Publishing Group
DOI: 10.1038/s41598-022-15207-5

Other (1)

Optogenetic control of pheromone gradients reveals functional limits of mating behavior in budding yeast

Author(s): Alvaro Banderas, Maud Hofmann, Celine Cordier, Matthias Le Bec, Carolina Elizondo, Lionel Chiron, Sylvain Pouzet, Vittore Scolari, Pascal Hersen
Published in: BioRxiv, 2024
Publisher: BioRXiv
DOI: 10.1101/2024.02.06.578657