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Stability and dynamics at different spatial scales: From physiology to Alzheimer's degeneration

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Publications

Imbalance between firing homeostasis and synaptic plasticity drives early-phase Alzheimer’s disease

Author(s): Boaz Styr, Inna Slutsky
Published in: Nature Neuroscience, Issue 21/4, 2018, Page(s) 463-473, ISSN 1097-6256
DOI: 10.1038/s41593-018-0080-x

Mitochondrial Regulation of the Hippocampal Firing Rate Set Point and Seizure Susceptibility

Author(s): Boaz Styr, Nir Gonen, Daniel Zarhin, Antonella Ruggiero, Refaela Atsmon, Neta Gazit, Gabriella Braun, Samuel Frere, Irena Vertkin, Ilana Shapira, Michal Harel, Leore R. Heim, Maxim Katsenelson, Ohad Rechnitz, Saja Fadila, Dori Derdikman, Moran Rubinstein, Tamar Geiger, Eytan Ruppin, Inna Slutsky
Published in: Neuron, Issue 102(5), 2019, Page(s) 1009–1024.e8, ISSN 0896-6273
DOI: 10.1016/j.neuron.2019.03.045

Secreted amyloid-β precursor protein functions as a GABA B R1a ligand to modulate synaptic transmission

Author(s): Heather C. Rice, Daniel de Malmazet, An Schreurs, Samuel Frere, Inge Van Molle, Alexander N. Volkov, Eline Creemers, Irena Vertkin, Julie Nys, Fanomezana M. Ranaivoson, Davide Comoletti, Jeffrey N. Savas, Han Remaut, Detlef Balschun, Keimpe D. Wierda, Inna Slutsky, Karl Farrow, Bart De Strooper, Joris de Wit
Published in: Science, Issue 363/6423, 2019, Page(s) eaao4827, ISSN 0036-8075
DOI: 10.1126/science.aao4827

Alzheimer’s Disease: From Firing Instability to Homeostasis Network Collapse

Author(s): Samuel Frere, Inna Slutsky
Published in: Neuron, Issue 97/1, 2018, Page(s) 32-58, ISSN 0896-6273
DOI: 10.1016/j.neuron.2017.11.028