Objective
In eukaryotes, the tagging of proteins with ubiquitin typically leads to their subsequent recognition and degradation by the 26S proteasome. The proteolysis of some proteins is triggered by distinct environmental and developmental cues to control the abundance of crucial cellular regulators. Protein ubiquitination can also be involved in protein activation, protein trafficking, DNA repair and regulation of transcription and translation via mono-ubiquitination and non-canonical ubiquitination.
In plants, genetic analysis has identified many ubiquitin/26S (Ub/26S) related genes that regulate various developmental pathways. Recent evidence indicates that protein ubiquitination plays a crucial role in plant disease resistance. However, only a few proteins targeted for ubiquitination upon specific stimuli and developmental processes were identified. No proteins, targeted for ubiquitination upon pathogen infection, were identified in plants. These proteins are potential repressors of defence responses that are removed by ubiquitin-mediated proteolysis, or proteins that need to be activated by mono-ubiquitination.
Therefore, developing novel systems for isolating and identifying plant ubiquitinated proteins is essential for furthering our understanding of the biological significance of the Ub/26S system in plant disease resistance and development.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
- natural sciences biological sciences genetics DNA
- natural sciences biological sciences biochemistry biomolecules proteins
You need to log in or register to use this function
Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
FP6-2002-MOBILITY-5
See other projects for this call
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Coordinator
NORWICH
United Kingdom
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.