Dissecting the Function of Multiple Polycomb Group Complexes in Establishing Transcriptional Identity

Project Information

DissectPcG

Grant agreement ID: 725268

DOI

10.3030/725268

Project closed

EC signature date 20 June 2017

Start date 1 November 2017

End date 30 June 2023

Funded under

• EXCELLENT SCIENCE - European Research Council (ERC)

Total cost

€ 2 000 000,00

EU contribution

€ 2 000 000,00

Coordinated by

UNIVERSITA DEGLI STUDI DI MILANO
Italy

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Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Publications

Peer reviewed articles (6)

BAP1 enhances Polycomb repression by counteracting widespread H2AK119ub1 deposition and chromatin condensation

Author(s): Eric Conway, Federico Rossi, Daniel Fernandez-Perez, Eleonora Ponzo, Karin Johanna Ferrari, Marika Zanotti, Daria Manganaro, Simona Rodighiero, Simone Tamburri, Diego Pasini
Published in: Molecular Cell, Issue 10972765, 2021, ISSN 1097-2765
Publisher: Cell Press
DOI: 10.1016/j.molcel.2021.06.020

Histone H2AK119 Mono-Ubiquitination Is Essential for Polycomb-Mediated Transcriptional Repression

Author(s): Simone Tamburri, Elisa Lavarone, Daniel Fernández-Pérez, Eric Conway, Marika Zanotti, Daria Manganaro, Diego Pasini
Published in: Molecular Cell, Issue 77/4, 2020, Page(s) 840-856.e5, ISSN 1097-2765
Publisher: Cell Press
DOI: 10.1016/j.molcel.2019.11.021

Loss of PRC1 activity in different stem cell compartments activates a common transcriptional program with cell type–dependent outcomes

Author(s): Silvia Pivetti, Daniel Fernandez-Perez, Alessandro D’Ambrosio, Caterina Maria Barbieri, Daria Manganaro, Alessandra Rossi, Laura Barnabei, Marika Zanotti, Andrea Scelfo, Fulvio Chiacchiera, Diego Pasini
Published in: Science Advances, Issue 5/5, 2019, Page(s) eaav1594, ISSN 2375-2548
Publisher: American Association for the Advancement of Science
DOI: 10.1126/sciadv.aav1594

Dissecting the role of H3K27 acetylation and methylation in PRC2 mediated control of cellular identity

Author(s): Elisa Lavarone, Caterina M. Barbieri, Diego Pasini
Published in: Nature Communications, Issue 10/1, 2019, ISSN 2041-1723
Publisher: Nature Publishing Group
DOI: 10.1038/s41467-019-09624-w

Functional Landscape of PCGF Proteins Reveals Both RING1A/B-Dependent-and RING1A/B-Independent-Specific Activities

Author(s): Andrea Scelfo, Daniel Fernández-Pérez, Simone Tamburri, Marika Zanotti, Elisa Lavarone, Monica Soldi, Tiziana Bonaldi, Karin Johanna Ferrari, Diego Pasini
Published in: Molecular Cell, Issue 74/5, 2019, Page(s) 1037-1052.e7, ISSN 1097-2765
Publisher: Cell Press
DOI: 10.1016/j.molcel.2019.04.002

Intestinal differentiation involves cleavage of histone H3 N-terminal tails by multiple proteases

Author(s): Karin Johanna Ferrari, Simona Amato, Roberta Noberini, Cecilia Toscani, Daniel Fernández-Pérez, Alessandra Rossi, Pasquale Conforti, Marika Zanotti, Tiziana Bonaldi, Simone Tamburri, Diego Pasini
Published in: Nucleic Acids Research, Issue 49/2, 2021, Page(s) 791-804, ISSN 0305-1048
Publisher: Oxford University Press
DOI: 10.1093/nar/gkaa1228