Periodic Reporting for period 1 - HYPERTRANS (HYPERTRANS: Transport of hyperpolarized substrates for metabolic MR imaging)
Reporting period: 2016-12-01 to 2018-05-31
Metabolic imaging can provide new insights in biological pathways in different diseases. Our long-term ambition is to make hyperpolarized substrates for metabolic imaging with MRI available for every clinical institution. The short-term goal to be reached first, is to provide the technique of dynamic metabolic imaging to the wide scientific (pre-)clinical community. We started implementation of a concept in which we can polarize substrates at one central location and store these hyperpolarized substrates for transport and use in other academic institutions. This solution overcomes the current need for an on-site dynamic nuclear polarizer when performing preclinical metabolic imaging with MRI, allows an efficient use of resources, and enables scientific institutions to easily adopt this powerful emerging imaging tool.