Objective
The project sets out to develop and validate a dosimetric model relating to the "harmfulness" associated with inhaling coalmine dusts. Its purpose is to provide a quantitative, scientific basis for risk assessment, standards setting, design of sampling strategies and hazard control.
This model, obtained from animal studies, will be validated by reference to the known epidemiology of chest illness among mineworkers.
The work involves compiling the information already available on:
a) the physical behaviour of airborne particles and their entry into the respiratory tract during breathing.
b) the kinetics of their deposition, distribution, clearance and storage;
c) the kinetics of the biological responses to the presence of particles in the lung;
d) the pathology and particulate burdens of lungs removed from people post-mortem; and
e) the epidemiological evidence linking dust-related diseases with occupational exposure histories of working populations.
METHODS AND MEANS BY WHICH THE AIMS ARE TO BE ACHIEVED
The main thrust of the project involves an exercise in mathematical modelling and statistics, using data (and other information) drawn from wide-ranging studies.
For this research, the required computing and database facilities and statistical software are already in place.
One piece of additional experimental work is required to complete the data set required for development of the desired dosimetric model: namely, the cell responses to relevant coalmine dusts in a form suitable for application in the dosimetric rationale.
Fields of science (EuroSciVoc)
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Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
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Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Data not available
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Coordinator
EH8 9SU Edinburgh
United Kingdom
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.