Transcribing the processes of life: Visual Genetics

Livrables

Alkyne-tagged molecules

D2.1: Development and synthesis of alkyne-tagged morpholinos and nucleotide analogues (month 12)

Dissemination plan

D7.1. Generation of the Dissemination and Communication Plan (month 2)

Transcription monitoring in mouse in vitro

Detection of single gene transcription by SRS in mouse neurons in vitro month 40

Action check meeting

D7.5. Action check meeting (month 13, 48)

Recording

Optimizing microscopy recording conditions

Summer school and workshop

D7.3.. Organization of summer schools and workshop (month 12, 24, 36, 48)

Website and outreach

D7.4. VISGEN website and Outreach activity plan (month 3)

Publications

Possible involvement of TGF-β-SMAD-mediated epithelial-mesenchymal transition in pro-metastatic property of PAX6

Auteurs: M.Jin, D.Gao, R.Wang, A.Sík and K.Liu
Publié dans: Oncol Report, 2020, ISSN 1021-335X
Éditeur: Demetrios A. Spandidos Ed. & Pub.
DOI: 10.3892/or.2020.7644

Cellular localization of melatonin receptor Mel1b in pigeon retina

Auteurs: W.Sheng, S.Weng, A.Sík, and K.Liu
Publié dans: Neuropeptides, 2019, ISSN 0143-4179
Éditeur: Churchill Livingstone
DOI: 10.1016/j.npep.2019.101974

Whole brain functional recordings at cellular resolution in zebrafish larvae with 3D scanning multiphoton microscopy.

Auteurs: Matteo Bruzzone; Enrico Chiarello; Marco Albanesi; Maria Elena Miletto Petrazzini; Aram Megighian; Claudia Lodovichi; Marco Dal Maschio
Publié dans: Scientific Reports, Numéro 1, 2021, ISSN 2045-2322
Éditeur: Nature Publishing Group
DOI: 10.1038/s41598-021-90335-y

Anticonvulsant activity of melatonin and its success in ameliorating epileptic comorbidity-like symptoms in zebrafish

Auteurs: Q.Ren, D.Gao, L.Mou, S.Zhang, M.Zhang, N.Li, A.Sík, M.Jin, K.Liu
Publié dans: Eur J Pharmacol, 2021, ISSN 0014-2999
Éditeur: Elsevier BV
DOI: 10.1016/j.ejphar.2021.174589

A cell cycle-coordinated Polymerase II transcription compartment encompasses gene expression before global genome activation

Auteurs: Yavor Hadzhiev, Haseeb K. Qureshi, Lucy Wheatley, Ledean Cooper, Aleksandra Jasiulewicz, Huy Van Nguyen, Joseph W. Wragg, Divyasree Poovathumkadavil, Sascha Conic, Sarah Bajan, Attila Sik, György Hutvàgner, Làszlò Tora, Agnieszka Gambus, John S. Fossey, Ferenc Müller
Publié dans: Nature Communications, Numéro 10/1, 2019, ISSN 2041-1723
Éditeur: Nature Publishing Group
DOI: 10.1038/s41467-019-08487-5

Involvement of peroxisome proliferator-activated receptor γ in anticonvulsant activity of α-asaronol against pentylenetetrazole-induced seizures in zebrafish

Auteurs: Meng Jin, Baoyue Zhang, Ying Sun, Shanshan Zhang, Xiang Li, Attila Sik, Yajun Bai, Xiaohui Zheng, Kechun Liu
Publié dans: Neuropharmacology, Numéro 04 September 2019, 2019, Page(s) 107760, ISSN 0028-3908
Éditeur: Pergamon Press Ltd.
DOI: 10.1016/j.neuropharm.2019.107760

α-asarone induces cardiac defects and QT prolongation through mitochondrial apoptosis pathway in zebrafish

Auteurs: X.Shang, X.Ji, J.Dang, L.Wang, C.Sun, K.Liu, A.Sík, M.Jin
Publié dans: Toxicology Letters, 2020, ISSN 0378-4274
Éditeur: Elsevier BV
DOI: 10.1016/j.toxlet.2020.02.003

Anti-inflammatory associated protective mechanism of berberine and its derivatives on attenuating pentylenetetrazole-induced seizures in Zebrafish

Auteurs: B.Zhang, L.Wang, X.Ji, S.Zhang, R.Wang, J.Dang, K.Liu, A.Sík and M.Jin
Publié dans: Journal of Neuroimmune Pharmacology, 2020, ISSN 1557-1890
Éditeur: Springer Verlag
DOI: 10.1007/s11481-019-09902-w

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