Cost Effective Personalised Compression Therapy for Chronic Venous Insufficiency with Accurate Pressure Delivery for Comfort and Efficacy of Treatment

Project Information

ISOBAR

Grant agreement ID: 736205

DOI

10.3030/736205

Project closed

EC signature date 12 July 2016

Start date 1 August 2016

End date 31 January 2017

Funded under

• INDUSTRIAL LEADERSHIP - Leadership in enabling and industrial technologies – Nanotechnologies

Total cost

€ 71 429,00

EU contribution

€ 50 000,00

Coordinated by

ADVANCED THERAPEUTIC MATERIALS LTD
United Kingdom

Periodic Reporting for period 1 - ISOBAR (Cost Effective Personalised Compression Therapy for Chronic Venous Insufficiency with AccuratePressure Delivery for Comfort and Efficacy of Treatment)

Reporting period: 2016-08-01 to 2017-01-31

Summary of the context and overall objectives of the project

The ISOBAR concept is based on a novel approach of compression therapy delivery, which is essential for successful treatment and management of many common circulatory disorders (Chronic venous insufficiency, Lymphoedema and DVT prophylaxis). Chronic venous insufficiency (CVI) is a condition in which the blood, which normally would flow back to the heart from the veins in the lower limbs, does not do so efficiently because the valves in the veins are damaged or absent. It affects up to 50% of the adult population, and it is estimated that 1% of the UK population will suffer from leg ulceration during their lifetime. It is estimated that the annual cost of treatment for CVI in the European Union is €6.5 billion, and in the UK only the annual cost is up to €850 million.

Work performed from the beginning of the project to the end of the period covered by the report and main results achieved so far

The ISOBAR technology is currently at TRL 7. After reviewing all of the information available on the vascular healthcare market, we have concluded that the European market, especially UK, France and Italy, will be the main focus for ISOBAR technology commercialization for the next 3 years. We have also evaluated potential partners for the software development (Imfusion GmbH, Germany). In addition, we identified ANR Manufacturing from Buckinghamshire, UK as a partner to assemble scanners from parts specified by ATM. We compiled a business plan, and as part of that, we created a risk analysis to help to form the basis for a Phase 2 application. ATM will therefore proceed with our plans to carry out the development project and submit a Phase 2 application to continue the route to commercialisation.

Progress beyond the state of the art and expected potential impact (including the socio-economic impact and the wider societal implications of the project so far)

The ISOBAR technology will offer a novel approach of compression therapy delivery with a structured compression garment that fits a patient precisely and delivers the prescribed pressure. Once fully developed, it will resolve all the problems associated with the current techniques and systems for delivering compression therapies. The problems associated with the current methods: difficult applications and frequent measurement errors, constant supervision by trained clinicians required, numerous issues with therapy delivery, low pressure delivery and design problems, social isolation for the patients.

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