METAbolism analysis made easy for CELL Translational Medicine

Project Information

METACELL-TM

Grant agreement ID: 737978

DOI 10.3030/737978

Project closed

EC signature date 17 November 2016

Start date 1 November 2016

End date 30 April 2019

Funded under

• Horizon 2020 Framework Programme

Total cost € 3 313 827,50

EU contribution € 2 459 616,13

Coordinated by

LUXCEL BIOSCIENCES LTD
Ireland

Deliverables

Other (2)

Sales Account Manager Recruitment
Hosted ‘WEB-PORTAL’, developed and launched

Publications

Other (9)

The Measurement of Cellular Bioenergetics at Defined Steady-State Oxygen Concentrations: A Novel Microplate Based Method

Author(s): D.L. Hoffman, C.A. Peters , J. Hynes
Published in: 2016
Publisher: MITOX Conference

The importance of cellular oxygenation measurements in the analysis of hypoxia-induced signalling and related metabolic adaptation

Author(s): M. Potter, J. Hynes, A. Nijhuis, C. Carey, I. Hayes, C. Zois, A. Harris, H. Keun, K. Morten
Published in: 2017
Publisher: American Association of Cancer Research; New Horizons in Cancer Research: Research Propelling Cancer Prevention and Cures

High-throughput in vitro ischemia-reperfusion model with real-time monitoring of cellular oxygenation and reactive oxygen species generation

Author(s): C. Carey, R. Kettenhofen, M. Schneider, M. Schwalfenberg, J. Hynes
Published in: 2017
Publisher: British Society of Cardiovascular Research: Cardiac Metabolic Disorders and Mitochondrial Dysfunction

A functional high-throughput screen for drug-induced modulation of fatty acid oxidation

Author(s): C. Carey, T. Xinru, Y. Will, J. Hynes
Published in: 2017
Publisher: Society of Toxicology Annual Meeting

Investigating Drug Induced Cardiomyocyte Dysfunction through Combined Analysis of Beating, Metabolic Flux and Cellular Oxygenation

Author(s): C. Carey, C. Bertinetti-Lapatki, R. Kettenhofen, A. Roth, J Hynes.
Published in: 2017
Publisher: Society of Toxicology Annual Meeting

Microplate-based ischemia-reperfusion model with real-time monitoring of cellular oxygenation and reactive oxygen species generation

Author(s): C. Carey, R. Kettenhofen, M. Schneider, J. Hynes
Published in: 2017
Publisher: Society of Redox Biology and Medicine Annual Meeting

Modelling tumour hypoxia through parallel analysis of cellular oxygenation, glycolytic flux and mitochondrial function

Author(s): M. Schwalfenberg, R. McGarrigle, C. Carey, J. Hynes
Published in: 2017
Publisher: MITOX Conference

The CLARIOstar® with ACU exposes cells to ischemiareperfusion conditions and monitors their oxygenation

Author(s): C. Wark, C. Carey, R. Kettenhofen, M. Schwalfenberg, J. Hynes
Published in: 2018
Publisher: SLAS 2018

Multiplexed Screening of Drug-Induced Mitochondrial Dysfunction and Cytotoxicity

Author(s): M. Schwalfenberg, R. McGarrigle, C. Carey and J. Hynes
Published in: 2019
Publisher: SOT

Book chapters (1)

Chapter 8 Monitoring of extracellular and intracellular O2 on a time-resolved fluorescence plate reader in Quenched-phosphorescence detection of molecular oxygen. Applications in life sciences.

Author(s): Michelle Potter, Tiffany A. Lodge, Karl J. Morten
Published in: Detection Science Series Royal Society of Chemistry, Issue Detection Science number 11, 2018, Page(s) 175-192, ISSN 2052-3068
Publisher: The Royal Society of Chemistry