Objective The project will clinically validate a smart biopsy solution that provides real-time direct tissue characterization at the tip of the needle, which can be displayed on the biopsy system screen as well as on the screen of the imaging system used to guide the biopsy, based on data directly related to the disease stage and tissue type.The real-time tissue characterization will improve the accuracy of the diagnosis, reduce the understaging risk by 95%, reduce the false negative rate by 80%, reduce the number of repeat biopsies by 80% and the number of excisional open breast biopsies by 50%, thus improving the standard of care for breast cancer diagnosis. The project also supports the development of personalized medicine by identifying novel biomarkers for cancer tissue characterization (conductivity and permittivity measurements based on dielectric spectroscopy), which will help clinicians predicting individual patient risk profiles and follow-up requirements. The project results will therefore lead to improved diagnosis, reduced clinical risks associated with un-necessary biopsies, and ultimately reduce costs for health providers, while improving standard of care and quality of life for the patients. Estimated cost savings can reach 275M Euros for each 1M biopsies. The project will implement an open label, single arm, multi-centre, prospective, cohort validation study, performed at 3 sites in Israel, supporting the adoption by the medical community and the filing of CE certification applications. The project duration is 24 months and the total budget 3M Euros. Fields of science medical and health sciencesclinical medicineoncologybreast cancermedical and health sciencesclinical medicinesurgerysurgical proceduresmedical and health scienceshealth sciencespersonalized medicinemedical and health sciencesbasic medicinepharmacology and pharmacydrug resistancemultidrug resistancenatural sciencesphysical sciencesopticsspectroscopy Programme(s) H2020-EU.3.1. - SOCIETAL CHALLENGES - Health, demographic change and well-being Main Programme H2020-EU.3.1.3. - Treating and managing disease Topic(s) SMEInst-05-2016-2017 - Supporting innovative SMEs in the healthcare biotechnology sector Call for proposal H2020-SMEInst-2016-2017 See other projects for this call Sub call H2020-SMEINST-2-2016-2017 Funding Scheme SME-2 - SME instrument phase 2 Coordinator DUNE MEDICAL DEVICES LTD Net EU contribution € 3 032 500,00 Address 20 ALON HATAVOR 3088900 CAESAREA Israel See on map SME The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed. Yes Activity type Private for-profit entities (excluding Higher or Secondary Education Establishments) Links Contact the organisation Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Total cost € 3 032 500,00
