Skip to main content
European Commission logo print header

Exosome and ribosome coupling

Publications

The MTR4 helicase recruits nuclear adaptors of the human RNA exosome using distinct arch-interacting motifs

Author(s): Mahesh Lingaraju, Dennis Johnsen, Andreas Schlundt, Lukas M. Langer, Jérôme Basquin, Michael Sattler, Torben Heick Jensen, Sebastian Falk, Elena Conti
Published in: Nature Communications, Issue 10/1, 2019, Page(s) 3393, ISSN 2041-1723
Publisher: Nature Publishing Group
DOI: 10.1038/s41467-019-11339-x

The human SKI complex regulates channeling of ribosome-bound RNA to the exosome via an intrinsic gatekeeping mechanism.

Author(s): Alexander Kögel, Achim Keidel, Fabien Bonneau, Ingmar B. Schäfer, and Elena Conti.
Published in: Molecular Cell, Issue 82(4), 2022, Page(s) 756-769.e8, ISSN 1097-2765
Publisher: Cell Press
DOI: 10.1016/j.molcel.2022.01.009

Reconstitution of 3′ end processing of mammalian pre-mRNA reveals a central role of RBBP6.

Author(s): Moritz Schmidt, Florian Kluge, Felix Sandmeir, Uwe Kühn, Peter Schäfer, Christian Tüting, Christian Ihling, Elena Conti, and Elmar Wahle.
Published in: Genes and Development, Issue 36, 2022, Page(s) 195-209, ISSN 0890-9369
Publisher: Cold Spring Harbor Laboratory Press
DOI: 10.1101/gad.349217.121

Distinct and evolutionary conserved structural features of the human nuclear exosome complex

Author(s): Piotr Gerlach, Jan M Schuller, Fabien Bonneau, Jérôme Basquin, Peter Reichelt, Sebastian Falk, Elena Conti
Published in: eLife, Issue 7, 2018, ISSN 2050-084X
Publisher: eLife Sciences Publications
DOI: 10.7554/elife.38686

Structure of the nuclear exosome captured on a maturing preribosome

Author(s): Jan Michael Schuller, Sebastian Falk, Lisa Fromm, Ed Hurt, Elena Conti
Published in: Science, Issue 360/6385, 2018, Page(s) 219-222, ISSN 0036-8075
Publisher: American Association for the Advancement of Science
DOI: 10.1126/science.aar5428

Molecular Basis for poly(A) RNP Architecture and Recognition by the Pan2-Pan3 Deadenylase

Author(s): Ingmar B. Schäfer, Masami Yamashita, Jan Michael Schuller, Steffen Schüssler, Peter Reichelt, Mike Strauss, Elena Conti
Published in: Cell, Issue 177/6, 2019, Page(s) 1619-1631.e21, ISSN 0092-8674
Publisher: Cell Press
DOI: 10.1016/j.cell.2019.04.013

Structure and regulation of the Nuclear Exosome Targeting Complex guide RNA substrates to the exosome.

Author(s): Gerlach P., Garland W., Lingaraju M., Salerno-Kochan A., Bonneau F., Basquin J., Jensen T.H. and Conti E. (2022).
Published in: Molecular Cell, Issue 82/13, 2022, Page(s) 2505-2518.e7, ISSN 1097-2765
Publisher: Cell Press
DOI: 10.1016/j.molcel.2022.04.011

Structure of substrate-bound SMG1-8-9 kinase complex reveals molecular basis for phosphorylation specificity

Author(s): Lukas M Langer, Yair Gat, Fabien Bonneau, Elena Conti
Published in: eLife, Issue 9, 2020, Page(s) 57127, ISSN 2050-084X
Publisher: eLife Sciences Publications
DOI: 10.7554/elife.57127

Cryo-EM reconstructions of inhibitor-bound SMG1 kinase reveal an autoinhibitory state dependent on SMG8.

Author(s): Lukas M. Langer, Fabien Bonneau, Yair Gat, and Elena Conti
Published in: eLife, Issue 10, 2021, Page(s) e72353, ISSN 2050-084X
Publisher: eLife Sciences Publications
DOI: 10.7554/elife.72353

To Process or to Decay: A Mechanistic View of the Nuclear RNA Exosome

Author(s): Mahesh Lingaraju, Jan M. Schuller, Sebastian Falk, Piotr Gerlach, Fabien Bonneau, Jérôme Basquin, Christian Benda, Elena Conti
Published in: Cold Spring Harbor Symposia on Quantitative Biology, Issue 84, 2019, Page(s) 155-163, ISSN 0091-7451
Publisher: Cold Spring Harbor Laboratory Press
DOI: 10.1101/sqb.2019.84.040295

Searching for OpenAIRE data...

There was an error trying to search data from OpenAIRE

No results available