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Advanced clinical photoacoustic imaging systems based on optical microresonator detection

Objective

Photoacoustic imaging is widely viewed as one of the most exciting and promising biomedical imaging techniques to have emerged in recent years. It offers major opportunities for increasing our understanding of basic biological processes at an anatomical, physiological and molecular level, and for improving the clinical diagnosis and treatment of cancer and other major diseases. The aim of this project is to develop and evaluate a new generation of advanced photoacoustic scanners for clinical photoacoustic imaging based on a novel, highly sensitive, optical microresonator ultrasound sensor. This type of sensor offers the prospect of a major step forward in terms of imaging performance by providing orders of magnitude higher sensitivity than equivalently sized conventional detectors with the necessary broadband frequency response and small element size for high image quality. As a consequence, it promises greater penetration depth and improved image quality than possible with current state-of-the-art photoacoustic scanners. This will pave the way for in vivo high resolution human imaging at depths currently unattainable, opening up entirely new clinical applications in oncology, cardiovascular medicine, regenerative medicine and other areas which have hitherto been impossible due to hardware limitations. The project will involve the development of novel polymer optical microresonator sensors, advanced parallelised optical read-out schemes for real-time image acquisition, and engineering complete imaging instruments for use in clinical studies. These instruments will then be evaluated in a variety of clinical contexts including the assessment of skin cancer, head and neck cancers, cardiovascular disease and reconstructive surgery.

Fields of science (EuroSciVoc)

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Keywords

Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)

Programme(s)

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Topic(s)

Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.

Funding Scheme

Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.

ERC-ADG - Advanced Grant

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Call for proposal

Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.

(opens in new window) ERC-2016-ADG

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Host institution

UNIVERSITY COLLEGE LONDON
Net EU contribution

Net EU financial contribution. The sum of money that the participant receives, deducted by the EU contribution to its linked third party. It considers the distribution of the EU financial contribution between direct beneficiaries of the project and other types of participants, like third-party participants.

€ 2 163 061,00
Address
GOWER STREET
WC1E 6BT LONDON
United Kingdom

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Region
London Inner London — West Camden and City of London
Activity type
Higher or Secondary Education Establishments
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Total cost

The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.

€ 2 163 061,00

Beneficiaries (1)

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