Advanced clinical photoacoustic imaging systems based on optical microresonator detection

Project Information

Photoclin

Grant agreement ID: 741149

DOI

10.3030/741149

Project closed

EC signature date 21 August 2017

Start date 1 December 2017

End date 30 April 2025

Funded under

EXCELLENT SCIENCE - European Research Council (ERC)

Total cost

€ 2 163 061,00

EU contribution

€ 2 163 061,00

2 163 061,00

Coordinated by

UNIVERSITY COLLEGE LONDON
United Kingdom

CORDIS provides links to public deliverables and publications of HORIZON projects.

Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Publications

A fast all-optical 3D photoacoustic scanner for clinical vascular imaging

Author(s): N. T. Huynh, E. Zhang, O. Francies, F. Kuklis, T. Allen, J. Zhu, O. Abeyakoon, F. Lucka, M. Betcke, J. Jaros, S. Arridge, B. Cox, A. A. Plumb, P. Beard
Published in: Nature Biomedical Engineering, Issue 9, 2025, Page(s) 638-655, ISSN 2157-846X
Publisher: Springer Science and Business Media LLC
DOI: 10.1038/s41551-024-01247-x

Multimodal optical ultrasound imaging: Real-time imaging under concurrent CT or MRI

Author(s): Fraser T. Watt, Vivek Muthurangu, Jennifer Steeden, Eleanor C. Mackle, Adrien E. Desjardins, Edward Z. Zhang, Paul C. Beard, Erwin J. Alles
Published in: APL Photonics, Issue 9, 2025, ISSN 2378-0967
Publisher: AIP Publishing
DOI: 10.1063/5.0225554

Analysis of the Directivity of Glass-Etalon Fabry–Pérot Ultrasound Sensors

Author(s): Danny R. Ramasawmy, Eleanor Martin, James A. Guggenheim, Edward Z. Zhang, Paul C. Beard, Bradley E. Treeby, Ben T. Cox
Published in: IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control, Issue 66/9, 2019, Page(s) 1504-1513, ISSN 0885-3010
Publisher: Institute of Electrical and Electronics Engineers
DOI: 10.1109/tuffc.2019.2921735

Sustained real-time and video-rate interventional optical ultrasound imaging

Author(s): Robert M. Stafford-Williams, Richard J. Colchester, Semyon Bodian, Seán Cardiff, Efthymios Maneas, Edward Z. Zhang, Paul C. Beard, Manish K. Tiwari, Adrien E. Desjardins, Erwin J. Alles
Published in: Journal of Biomedical Optics, Issue 30, 2025, ISSN 1083-3668
Publisher: S P I E - International Society for Optical Engineering
DOI: 10.1117/1.jbo.30.3.036005

Freehand and video-rate all-optical ultrasound imaging

Author(s): Erwin J. Alles, Eleanor C. Mackle, Sacha Noimark, Edward Z. Zhang, Paul C. Beard, Adrien E. Desjardins
Published in: Ultrasonics, Issue 116, 2025, Page(s) 106514, ISSN 0041-624X
Publisher: Elsevier BV
DOI: 10.1016/j.ultras.2021.106514

Mitigating the Limited View Problem in Photoacoustic Tomography for a Planar Detection Geometry by Regularized Iterative Reconstruction

Author(s): Jiaqi Zhu, Nam Huynh, Olumide Ogunlade, Rehman Ansari, Felix Lucka, Ben Cox, Paul Beard
Published in: IEEE Transactions on Medical Imaging, Issue 42, 2023, Page(s) 2603-2615, ISSN 0278-0062
Publisher: Institute of Electrical and Electronics Engineers
DOI: 10.1109/tmi.2023.3271390

High-resolution imaging of ultrasonic fields through a multimode optical fiber

Author(s): Benjamin Keenlyside, Dylan Marques, David B. Phillips, Edward Zhang, Paul Beard, James Guggenheim
Published in: Physical Review Applied, Issue 24, 2025, ISSN 2331-7019
Publisher: American Physical Society (APS)
DOI: 10.1103/nrzh-hqsh

Single-shot hybrid photoacoustic-fluorescent microendoscopy through a multimode fiber with wavefront shaping

Author(s): Sylvain Mezil, Antonio M. Caravaca-Aguirre, Edward Z. Zhang, Philippe Moreau, Irène Wang, Paul C. Beard, Emmanuel Bossy
Published in: Biomedical Optics Express, Issue 11/10, 2020, Page(s) 5717, ISSN 2156-7085
Publisher: The Optical Society
DOI: 10.1364/boe.400686

Numerical model of light propagation through Fabry-Perot etalons composed of interfaces with non-planar surface topography

Author(s): Dylan M. Marques, James A. Guggenheim, Peter R. T. Munro
Published in: Optics Express, Issue 30, 2024, Page(s) 46294, ISSN 1094-4087
Publisher: Optical Society of America
DOI: 10.1364/oe.472308

Spatially resolved readout of a Fabry–Perot ultrasound sensor interrogated through a multimode optical fiber using wavefront shaping

Author(s): Benjamin Keenlyside, Dylan Marques, Nathaniel Redgewell, Maxim Cherkashin, Edward Zhang, Paul Beard, James Guggenheim
Published in: Applied Physics Letters, Issue 123, 2025, ISSN 0003-6951
Publisher: American Institute of Physics
DOI: 10.1063/5.0166826

Analysing the impact of non-parallelism in Fabry-Perot etalons through optical modelling

Author(s): Dylan M. Marques, James A. Guggenheim, Peter R. T. Munro
Published in: Optics Express, Issue 29, 2024, Page(s) 21603, ISSN 1094-4087
Publisher: Optical Society of America
DOI: 10.1364/oe.425487

Use of a flexible optical fibre bundle to interrogate a Fabry–Perot sensor for photoacoustic imaging

Author(s): Rehman Ansari, Edward Z. Zhang, Adrien E. Desjardins, Anna L. David, Paul C. Beard
Published in: Optics Express, Issue 27/26, 2019, Page(s) 37886, ISSN 1094-4087
Publisher: Optical Society of America
DOI: 10.1364/oe.27.037886

Towards clinical application of freehand optical ultrasound imaging

Author(s): Fraser T. Watt, Eleanor C. Mackle, Edward Z. Zhang, Paul C. Beard, Erwin J. Alles
Published in: Scientific Reports, Issue 14, 2024, ISSN 2045-2322
Publisher: Nature Publishing Group
DOI: 10.1038/s41598-024-69826-1

The visible and near-infrared optical absorption coefficient spectrum of Parylene C measured by transmitting light through thin films in liquid filled cuvettes

Author(s): James A. Guggenheim, Yuanyuan Lyu, Dylan M. Marques, Edward Z. Zhang, Paul C. Beard
Published in: Optical Materials Express, Issue 11, 2024, Page(s) 3854, ISSN 2159-3930
Publisher: Optical Society of America
DOI: 10.1364/ome.427952

Modelling Fabry-Pérot etalons illuminated by focussed beams

Author(s): Dylan M. Marques, James A. Guggenheim, Rehman Ansari, Edward Z. Zhang, Paul C. Beard, Peter R. T. Munro
Published in: Optics Express, Issue 28/5, 2020, Page(s) 7691, ISSN 1094-4087
Publisher: Optical Society of America
DOI: 10.1364/oe.382526

Estimating blood oxygenation from photoacoustic images: can a simple linear spectroscopic inversion ever work?

Author(s): Roman Hochuli, Lu An, Paul C. Beard, Benjamin T. Cox
Published in: Journal of Biomedical Optics, Issue 24/12, 2019, Page(s) 1, ISSN 1083-3668
Publisher: S P I E - International Society for Optical Engineering
DOI: 10.1117/1.jbo.24.12.121914

High pulse energy fibre laser as an excitation source for photoacoustic tomography

Author(s): Thomas J. Allen, Martin Berendt, Di Lin, Shaiful U. Alam, Nam T. Huynh, Edward Zhang, David J. Richardson, Paul C. Beard
Published in: Optics Express, Issue 28, 2024, Page(s) 34255, ISSN 1094-4087
Publisher: Optical Society of America
DOI: 10.1364/oe.401708

Single-pixel camera photoacoustic tomography

Author(s): Nam Huynh, Felix Lucka, Edward Zhang, Marta Betcke, Simon R. Arridge, Paul C. Beard, Benjamin T. Cox
Published in: Journal of Biomedical Optics, Issue 24/12, 2019, Page(s) 1, ISSN 1083-3668
Publisher: S P I E - International Society for Optical Engineering
DOI: 10.1117/1.jbo.24.12.121907

Dual-modality rigid endoscope for photoacoustic imaging and white light videoscopy

Author(s): Rehman Ansari, Edward Zhang, Paul Beard
Published in: Journal of Biomedical Optics, Issue 29, 2024, ISSN 1083-3668
Publisher: S P I E - International Society for Optical Engineering
DOI: 10.1117/1.jbo.29.2.020502

ABCD transfer matrix model of Gaussian beam propagation in plano-concave optical microresonators

Author(s): David Martin-Sanchez, Jing Li, Edward Z. Zhang, Paul C. Beard, James A. Guggenheim
Published in: Optics Express, Issue 31, 2024, Page(s) 16523, ISSN 1094-4087
Publisher: Optical Society of America
DOI: 10.1364/oe.484212

All-optical forward-viewing photoacoustic probe for high-resolution 3D endoscopy

Author(s): Rehman Ansari, Edward Z. Zhang, Adrien E. Desjardins, Paul C. Beard
Published in: Light: Science & Applications, Issue 7/1, 2018, ISSN 2047-7538
Publisher: Nature
DOI: 10.1038/s41377-018-0070-5

All-optical dual photoacoustic and optical coherence tomography intravascular probe

Author(s): Sunish J. Mathews, Callum Little, Christopher D. Loder, Roby D. Rakhit, Wenfeng Xia, Edward Z. Zhang, Paul C. Beard, Malcolm C. Finlay, Adrien E. Desjardins
Published in: Photoacoustics, Issue 11, 2018, Page(s) 65-70, ISSN 2213-5979
Publisher: Elsevier GmbH
DOI: 10.1016/j.pacs.2018.07.002

All-Optical Rotational Ultrasound Imaging

Author(s): Richard J. Colchester, Callum Little, George Dwyer, Sacha Noimark, Erwin J. Alles, Edward Z. Zhang, Christopher D. Loder, Ivan P. Parkin, Ioannis Papakonstantinou, Paul C. Beard, Malcolm C. Finlay, Roby D. Rakhit, Adrien E. Desjardins
Published in: Scientific Reports, Issue 9/1, 2019, ISSN 2045-2322
Publisher: Nature Publishing Group
DOI: 10.1038/s41598-019-41970-z

Reverberant cavity photoacoustic imaging

Author(s): M. D. Brown, E. Z. Zhang, B. E. Treeby, P. C. Beard, B. T. Cox
Published in: Optica, Issue 6/6, 2019, Page(s) 821, ISSN 2334-2536
Publisher: OSA
DOI: 10.1364/optica.6.000821

Monitoring neovascularization and integration of decellularized human scaffolds using photoacoustic imaging

Author(s): Olumide Ogunlade, Jasmine O.Y. Ho, Tammy L. Kalber, Robert E. Hynds, Edward Zhang, Sam M. Janes, Martin A. Birchall, Colin R. Butler, Paul Beard
Published in: Photoacoustics, Issue 13, 2019, Page(s) 76-84, ISSN 2213-5979
Publisher: Elsevier GmbH
DOI: 10.1016/j.pacs.2019.01.001

Non-iterative model-based inversion for low channel-count optical ultrasound imaging

Author(s): Fraser T. Watt, Andreas Hauptmann, Eleanor C. Mackle, Edward Z. Zhang, Paul C. Beard, Erwin J. Alles
Published in: The Journal of the Acoustical Society of America, Issue 156, 2025, Page(s) 3514-3522, ISSN 0001-4966
Publisher: Acoustical Society of America
DOI: 10.1121/10.0034450

Angular Airy function: a model of Fabry-Perot etalons illuminated by arbitrary beams

Author(s): Dylan M. Marques, James A. Guggenheim, Peter R. T. Munro
Published in: Optics Express, Issue 29, 2024, Page(s) 24144, ISSN 1094-4087
Publisher: Optical Society of America
DOI: 10.1364/oe.431362

Sensitive broadband ultrasound sensor based on a low-loss high-Q fused-silica plano-concave microresonator

Author(s): David Martín-Sánchez, Edward Z. Zhang, Zhixin Liu, James A. Guggenheim, Paul C. Beard
Published in: Optics Express, Issue 33, 2025, Page(s) 39875, ISSN 1094-4087
Publisher: Optical Society of America
DOI: 10.1364/oe.572433

An optical coherence photoacoustic microscopy system using a fiber optic sensor

Author(s): Shiyu Deng, Richard Haindl, Edward Zhang, Paul Beard, Eva Scheuringer, Caterina Sturtzel, Qian Li, Abigail J. Deloria, Harald Sattmann, Rainer A. Leitgeb, Yi Yuan, Leopold Schmetterer, Manojit Pramanik, Martin Distel, Wolfgang Drexler, Mengyang Liu
Published in: APL Photonics, Issue 6, 2025, ISSN 2378-0967
Publisher: AIP Publishing
DOI: 10.1063/5.0059351

Laser frequency noise characterization using high-finesse plano–concave optical microresonators

Author(s): David Martin-Sanchez, Edward Z. Zhang, Jake Paterson, James A. Guggenheim, Zhixin Liu, Paul C. Beard
Published in: Optics Letters, Issue 49, 2024, Page(s) 678, ISSN 0146-9592
Publisher: Optical Society of America
DOI: 10.1364/ol.510516

Longitudinal Photoacoustic Imaging of the Pharmacodynamic Effect of Vascular Targeted Therapy on Tumors

Author(s): S. Peter Johnson, Olumide Ogunlade, Mark F. Lythgoe, Paul Beard, R. Barbara Pedley
Published in: Clinical Cancer Research, Issue 25/24, 2019, Page(s) 7436-7447, ISSN 1078-0432
Publisher: American Association for Cancer Research
DOI: 10.1158/1078-0432.ccr-19-0360

Photoacoustic imaging of the human placental vasculature

Author(s): Efthymios Maneas, Rosalind Aughwane, Nam Huynh, Wenfeng Xia, Rehman Ansari, Mithun Kuniyil Ajith Singh, J. Ciaran Hutchinson, Neil J. Sebire, Owen J. Arthurs, Jan Deprest, Sebastien Ourselin, Paul C. Beard, Andrew Melbourne, Tom Vercauteren, Anna L. David, Adrien E. Desjardins
Published in: Journal of Biophotonics, Issue 13/4, 2020, ISSN 1864-063X
Publisher: Wiley - VCH Verlag GmbH & CO. KGaA
DOI: 10.1002/jbio.201900167

Holographic diffusers for endoluminal-scale optical ultrasound imaging

Author(s): Fraser T. Watt, Efthymios Maneas, Desta Chan, Edward Z. Zhang, Paul C. Beard, Erwin J. Alles
Published in: Journal of Biomedical Optics, Issue 31, 2026, ISSN 1083-3668
Publisher: S P I E - International Society for Optical Engineering
DOI: 10.1117/1.jbo.31.1.016006

Real-Time, Video-Rate and Depth-Resolved Imaging of Radio-Frequency Ablation Using All-Optical Ultrasound

Author(s): Erwin J Alles, Richard J Colchester, Yousuf Makki, Sacha Noimark, Edward Z Zhang, Paul C Beard, Malcolm C Finlay, Adrien E Desjardins
Published in: 2018 IEEE International Ultrasonics Symposium (IUS), 2020, Page(s) 1-9
Publisher: IEEE
DOI: 10.1109/ultsym.2018.8580211

Dual-Modality All-Optical Ultrasound and Photoacoustic Imaging Using Permanent Marker Ink

Author(s): Richard J Colchester, Sacha Noimark, Edward Z Zhang, Paul C Beard, Adrien E Desjardins
Published in: 2018 IEEE International Ultrasonics Symposium (IUS), 2020, Page(s) 1-4
Publisher: IEEE
DOI: 10.1109/ultsym.2018.8579904

Reconfigurable 1.5D Source Arrays for Improved Elevational Focussing in All-Optical Ultrasound Imaging

Author(s): Erwin J Alles, Sacha Noimark, Efthymia Papaevangelou, Edward Z Zhang, Paul C Beard, Adrien E Dcsjardins
Published in: 2018 IEEE International Ultrasonics Symposium (IUS), 2020, Page(s) 1-9
Publisher: IEEE
DOI: 10.1109/ultsym.2018.8580210

Broadband All-Optical Plane-Wave Ultrasound Imaging System Based on a Fabry–Perot Scanner

Author(s): Khoa Pham, Sacha Noimark, Nam Huynh, Edward Zhang, Filip Kuklis, Jiri Jaros, Adrien Desjardins, Ben Cox, Paul Beard
Published in: IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control, Issue 68, 2022, Page(s) 1007-1016, ISSN 0885-3010
Publisher: Institute of Electrical and Electronics Engineers
DOI: 10.1109/tuffc.2020.3028749

Searching for OpenAIRE data...

Publications

Download Download the content of the page