Publicaciones Peer reviewed articles (14) Metabolic resistance to the inhibition of mitochondrial transcription revealed by CRISPR-Cas9 screen. Autores: Mara Mennuni; Roberta Filograna; Andrea Felser; Andrea Felser; Nina A Bonekamp; Nina A Bonekamp; Patrick Giavalisco; Oleksandr Lytovchenko; Nils-Göran Larsson Publicado en: EMBO Reports, 2022, ISSN 1469-3178 Editor: European Molecular Biology Organization, Nature Portfolio DOI: 10.15252/embr.202153054 The mitochondrial single-stranded DNA binding protein is essential for initiation of mtDNA replication. Autores: Min Jiang; Min Jiang; Xie Xie; Xuefeng Zhu; Shan Jiang; Dusanka Milenkovic; Jelena Misic; Yonghong Shi; Nirwan Tandukar; Xinping Li; Ilian Atanassov; Louise Jenninger; Emily Hoberg; Sara Albarran-Gutierrez; Zsolt Szilagyi; Bertil Macao; Stefan J. Siira; Stefan J. Siira; Valerio Carelli; Jack D. Griffith; Claes M. Gustafsson; Thomas J. Nicholls; Aleksandra Filipovska; Aleksandra Filipovska; Nils-G Publicado en: Sci Adv, 2021, ISSN 2375-2548 Editor: AAAS DOI: 10.1126/sciadv.abf8631 Mitochondrial DNA copy number in human disease: the more the better? Autores: Roberta Filograna; Roberta Filograna; Mara Mennuni; Mara Mennuni; David Alsina; David Alsina; Nils-Göran Larsson; Nils-Göran Larsson Publicado en: Febs Letters, 2020, ISSN 1873-3468 Editor: Febs Letters DOI: 10.1002/1873-3468.14021 Modulation of mtDNA copy number ameliorates the pathological consequences of a heteroplasmic mtDNA mutation in the mouse Autores: Filograna Roberta, Koolmeister Coolmeister, Upadhyay Mamta, Pajak A, Clemente Paula, Wibom Rolf, Simard ML, Wredenberg Anna, Freyer Chris, Stewart Jim B, Larsson Nils-Göran Publicado en: Science Advances, 2019, ISSN 2375-2548 Editor: AAAS DOI: 10.1126/sciadv.aav9824 Neuronal metabolic rewiring promotes resilience to neurodegeneration caused by mitochondrial dysfunction Autores: E. Motori, I. Atanassov, S. M. V. Kochan, K. Folz-Donahue, V. Sakthivelu, P. Giavalisco, N. Toni, J. Puyal, N.-G. Larsson Publicado en: Science Advances, Issue 6/35, 2020, Page(s) eaba8271, ISSN 2375-2548 Editor: Science Advances DOI: 10.1126/sciadv.aba8271 FBXL 4 deficiency increases mitochondrial removal by autophagy Autores: David Alsina, Oleksandr Lytovchenko, Aleksandra Schab, Ilian Atanassov, Florian A Schober, Min Jiang, Camilla Koolmeister, Anna Wedell, Robert W Taylor, Anna Wredenberg, Nils‐Göran Larsson Publicado en: EMBO Molecular Medicine, Issue 12/7, 2020, ISSN 1757-4676 Editor: John Wiley & Sons Ltd. DOI: 10.15252/emmm.201911659 High levels of TFAM repress mammalian mitochondrial DNA transcription in vivo. Autores: Nina A. Bonekamp; Min Jiang; Min Jiang; Elisa Motori; Elisa Motori; Rodolfo Garcia Villegas; Camilla Koolmeister; Ilian Atanassov; Andrea Mesaros; Chan Bae Park; Nils-Göran Larsson; Nils-Göran Larsson Publicado en: Life Sci Alliance, 2021, ISSN 2575-1077 Editor: Rockefeller University Press DOI: 10.26508/lsa.202101034 Small-molecule inhibitors of human mitochondrial DNA transcription Autores: Nina A. Bonekamp, Bradley Peter, Hauke S. Hillen, Andrea Felser, Tim Bergbrede, Axel Choidas, Moritz Horn, Anke Unger, Raffaella Di Lucrezia, Ilian Atanassov, Xinping Li, Uwe Koch, Sascha Menninger, Joanna Boros, Peter Habenberger, Patrick Giavalisco, Patrick Cramer, Martin S. Denzel, Peter Nussbaumer, Bert Klebl, Maria Falkenberg, Claes M. Gustafsson, Nils-Göran Larsson Publicado en: Nature, Issue 588/7839, 2020, Page(s) 712-716, ISSN 0028-0836 Editor: Nature Publishing Group DOI: 10.1038/s41586-020-03048-z MitoRibo-Tag Mice Provide a Tool for In Vivo Studies of Mitoribosome Composition Autores: Jakob D. Busch, Miriam Cipullo, Ilian Atanassov, Ana Bratic, Eduardo Silva Ramos, Thomas Schöndorf, Xinping Li, Sarah F. Pearce, Dusanka Milenkovic, Joanna Rorbach, Nils-Göran Larsson Publicado en: Cell Reports, Issue 29/6, 2019, Page(s) 1728-1738.e9, ISSN 2211-1247 Editor: Cell Press DOI: 10.1016/j.celrep.2019.09.080 Mitochondrial fusion is required for regulation of mitochondrial DNA replication Autores: Eduardo Silva Ramos, Elisa Motori, Christian Brüser, Inge Kühl, Assa Yeroslaviz, Benedetta Ruzzenente, Johanna H. K. Kauppila, Jakob D. Busch, Kjell Hultenby, Bianca H. Habermann, Stefan Jakobs, Nils-Göran Larsson, Arnaud Mourier Publicado en: PLOS Genetics, Issue 15/6, 2019, Page(s) e1008085, ISSN 1553-7404 Editor: Public Library of Science DOI: 10.1371/journal.pgen.1008085 Modulation of mtDNA copy number ameliorates the pathological consequences of a heteroplasmic mtDNA mutation in the mouse Autores: R. Filograna, C. Koolmeister, M. Upadhyay, A. Pajak, P. Clemente, R. Wibom, M. L. Simard, A. Wredenberg, C. Freyer, J. B. Stewart, N. G. Larsson Publicado en: Science Advances, Issue 5/4, 2019, Page(s) eaav9824, ISSN 2375-2548 Editor: AAAS DOI: 10.1126/sciadv.aav9824 Mice lacking the mitochondrial exonuclease MGME1 develop inflammatory kidney disease with glomerular dysfunction Autores: Dusanka Milenkovic,Adrián Sanz-Moreno,Julia Calzada-Wack,Birgit Rathkolb,Oana Veronica Amarie,Raffaele Gerlini,Antonio Aguilar-Pimentel,Jelena Misic,Marie-Lune Simard,Eckhard Wolf,Helmut Fuchs,Valerie Gailus-Durner,Martin Hrabě de Angelis ,Nils-Göran Larsson Publicado en: PLoS Genetics, 2022, ISSN 1553-7390 Editor: Public Library of Science DOI: 10.1371/journal.pgen.1010190 Dinucleotide Degradation by REXO2 Maintains Promoter Specificity in Mammalian Mitochondria Autores: Thomas J. Nicholls, Henrik Spåhr, Shan Jiang, Stefan J. Siira, Camilla Koolmeister, Sushma Sharma, Johanna H.K. Kauppila, Min Jiang, Volkhard Kaever, Oliver Rackham, Andrei Chabes, Maria Falkenberg, Aleksandra Filipovska, Nils-Göran Larsson, Claes M. Gustafsson Publicado en: Molecular Cell, Issue 76/5, 2019, Page(s) 784-796.e6, ISSN 1097-2765 Editor: Cell Press DOI: 10.1016/j.molcel.2019.09.010 A role for BCL2L13 and autophagy in germline purifying selection of mtDNA Autores: Laura S Kremer, Lyuba V Bozhilova, Diana Rubalcava-Gracia, Roberta Filograna, Mamta Upadhyay, Camilla Koolmeister, Patrick F Chinnery, Nils-Göran Larsson Publicado en: PLOS Genetics, 2023, ISSN 1553-7390 Editor: Public Library of Science Buscando datos de OpenAIRE... Se ha producido un error en la búsqueda de datos de OpenAIRE No hay resultados disponibles
