The molecular and cellular logic of vertebrate neural development

Project Information

LogNeuroDev

Grant agreement ID: 742138

DOI 10.3030/742138

Project closed

EC signature date 4 December 2017

Start date 1 January 2018

End date 30 June 2023

Funded under

• EXCELLENT SCIENCE - European Research Council (ERC)

Total cost € 2 357 000,00

EU contribution € 2 357 000,00

Coordinated by

THE FRANCIS CRICK INSTITUTE LIMITED
United Kingdom

CORDIS provides links to public deliverables and publications of HORIZON projects.

Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Publications

Peer reviewed articles (12)

Tractable nonlinear memory functions as a tool to capture and explain dynamical behaviors

Author(s): Edgar Herrera-Delgado, James Briscoe, Peter Sollich
Published in: Physical Review Research, Issue 2/4, 2020, ISSN 2643-1564
Publisher: American Physical Society
DOI: 10.1103/physrevresearch.2.043069

Species-specific pace of development is associated with differences in protein stability

Author(s): Teresa Rayon; Despina Stamataki; Ruben Perez-Carrasco; Ruben Perez-Carrasco; Ruben Perez-Carrasco; Lorena Garcia-Perez; Christopher Barrington; Manuela Melchionda; Katherine Exelby; Jorge Lazaro; Victor L. J. Tybulewicz; Victor L. J. Tybulewicz; Elizabeth M. C. Fisher; James Briscoe
Published in: Science, Issue 1, 2020, ISSN 0036-8075
Publisher: American Association for the Advancement of Science
DOI: 10.1126/science.aba7667

A shared transcriptional code orchestrates temporal patterning of the central nervous system.

Author(s): Andreas Sagner; Andreas Sagner; Andreas Sagner; Isabel Zhang; Thomas Watson; Jorge Lazaro; Manuela Melchionda; James Briscoe
Published in: PLoS Biology, Issue 1, 2021, ISSN 1544-9173
Publisher: Public Library of Science
DOI: 10.1371/journal.pbio.3001450

Precision of tissue patterning is controlled by dynamical properties of gene regulatory networks.

Author(s): Katherine Exelby; Edgar Herrera-Delgado; Edgar Herrera-Delgado; Edgar Herrera-Delgado; Lorena Garcia Perez; Ruben Perez-Carrasco; Andreas Sagner; Andreas Sagner; Vicki Metzis; Vicki Metzis; Peter Sollich; Peter Sollich; James Briscoe
Published in: Development, Issue 1, 2019, ISSN 0950-1991
Publisher: The Company of Biologists Ltd.
DOI: 10.1242/dev.197566

Looking at neurodevelopment through a big data lens

Author(s): James Briscoe, Oscar Marín
Published in: Science, Issue 369/6510, 2020, Page(s) eaaz8627, ISSN 0036-8075
Publisher: American Association for the Advancement of Science
DOI: 10.1126/science.aaz8627

Dynamical landscapes of cell fate decisions

Author(s): M. Sáez; J. Briscoe; D. A. Rand
Published in: 2042-8898, Issue 1, 2022, ISSN 2042-8898
Publisher: Royal Society Publishing
DOI: 10.1098/rsfs.2022.0002

Nervous System Regionalization Entails Axial Allocation before Neural Differentiation

Author(s): Metzis V, Steinhauser S, Pakanavicius E, Gouti M, Stamataki D, Ivanovitch K, Watson T, Rayon T, Mousavy Gharavy SN, Lovell-Badge R, Luscombe NM, Briscoe J.
Published in: Cell, 2018, ISSN 0092-8674
Publisher: Cell Press
DOI: 10.1016/j.cell.2018.09.040

Statistically derived geometrical landscapes capture principles of decision-making dynamics during cell fate transitions.

Author(s): Meritxell Sáez; Meritxell Sáez; Robert Blassberg; Elena Camacho-Aguilar; Elena Camacho-Aguilar; Eric D. Siggia; David A. Rand; James Briscoe
Published in: Cell Systems, Issue 1, 2021, ISSN 2405-4712
Publisher: Cell Press
DOI: 10.1016/j.cels.2021.08.013

Establishing neuronal diversity in the spinal cord: a time and a place

Author(s): Andreas Sagner, James Briscoe
Published in: Development, Issue 146/22, 2019, Page(s) dev182154, ISSN 0950-1991
Publisher: The Company of Biologists Ltd.
DOI: 10.1242/dev.182154

Single cell transcriptomics reveals spatial and temporal dynamics of gene expression in the developing mouse spinal cord

Author(s): Julien Delile, Teresa Rayon, Manuela Melchionda, Amelia Edwards, James Briscoe, Andreas Sagner
Published in: Development, Issue 146/12, 2019, Page(s) dev173807, ISSN 0950-1991
Publisher: The Company of Biologists Ltd.
DOI: 10.1242/dev.173807

Neuronal differentiation influences progenitor arrangement in the vertebrate neuroepithelium

Author(s): Pilar Guerrero, Ruben Perez-Carrasco, Marcin Zagorski, David Page, Anna Kicheva, James Briscoe, Karen M. Page
Published in: Development, Issue 146/23, 2019, Page(s) dev176297, ISSN 0950-1991
Publisher: The Company of Biologists Ltd.
DOI: 10.1242/dev.176297

Developmental cell fate choice in neural tube progenitors employs two distinct cis-regulatory strategies

Author(s): Delás MJ, Kalaitzis CM, Fawzi T, Demuth M, Zhang I, Stuart HT, Costantini E, Ivanovitch K, Tanaka EM, Briscoe J.
Published in: Developemental Cell, 2023, ISSN 1534-5807
Publisher: Cell Press
DOI: 10.1016/j.devcel.2022.11.016

Other (3)

Neuronal differentiation affects tissue mechanics and progenitor arrangement in the vertebrate neuroepithelium

Author(s): Pilar Guerrero, Ruben Perez-Carrasco, Marcin Zagorski, David Page, Anna Kicheva, James Briscoe, Karen Page
Published in: BioRxiv, 2019
Publisher: BioRxiv
DOI: 10.1101/536342

Precision of Tissue Patterning is Controlled by Dynamical Properties of Gene Regulatory Networks

Author(s): Katherine Exelby, Edgar Herrera-Delgado, Lorena Garcia Perez, Ruben Perez-Carrasco, Andreas Sagner, Vicki Metzis, Peter Sollich, James Briscoe
Published in: BioRxiv, 2019
Publisher: BioRxiv
DOI: 10.1101/721043

Species-specific developmental timing is associated with global differences in protein stability in mouse and human

Author(s): Teresa Rayon, Despina Stamataki, Ruben Perez-Carrasco, Lorena Garcia-Perez, Christopher Barrington, Manuela Melchionda, Katherine Exelby, Victor Tybulewicz, Elizabeth M. C. Fisher, James Briscoe
Published in: Biorxiv, 2019
Publisher: Biorxiv
DOI: 10.1101/2019.12.29.889543