Interaction and feedback between cell mechanics and fate specification in vertebrate gastrulation

Project Information

MECSPEC

Grant agreement ID: 742573

DOI 10.3030/742573

Project closed

EC signature date 12 June 2017

Start date 1 July 2017

End date 30 June 2022

Funded under

• EXCELLENT SCIENCE - European Research Council (ERC)

Total cost € 2 306 862,00

EU contribution € 2 306 862,00

Coordinated by

INSTITUTE OF SCIENCE AND TECHNOLOGY AUSTRIA
Austria

Publications

Peer reviewed articles (10)

Apical contacts stemming from incomplete delamination guide progenitor cell allocation through a dragging mechanism.

Author(s): Eduardo Pulgar; Cornelia Schwayer; Néstor Guerrero; Loreto López; Susana Márquez; Steffen Härtel; Rodrigo Soto; Carl-Philipp Heisenberg; Miguel L. Concha
Published in: eLife, Issue 2050084X, 2021, ISSN 2050-084X
Publisher: eLife Sciences Publications
DOI: 10.7554/elife.66483

Fluidization-mediated tissue spreading by mitotic cell rounding and non-canonical Wnt signalling

Author(s): Nicoletta I. Petridou, Silvia Grigolon, Guillaume Salbreux, Edouard Hannezo, Carl-Philipp Heisenberg
Published in: Nature Cell Biology, Issue 21/2, 2019, Page(s) 169-178, ISSN 1465-7392
Publisher: Nature Publishing Group
DOI: 10.1038/s41556-018-0247-4

Lateral Inhibition in Cell Specification Mediated by Mechanical Signals Modulating TAZ Activity

Author(s): Peng Xia, Daniel Gütl, Vanessa Zheden, Carl-Philipp Heisenberg
Published in: Cell, 2019, ISSN 0092-8674
Publisher: Cell Press
DOI: 10.1016/j.cell.2019.01.019

Bulk Actin Dynamics Drive Phase Segregation in Zebrafish Oocytes

Author(s): Shayan Shamipour, Roland Kardos, Shi-Lei Xue, Björn Hof, Edouard Hannezo, Carl-Philipp Heisenberg
Published in: Cell, Issue 177/6, 2019, Page(s) 1463-1479.e18, ISSN 0092-8674
Publisher: Cell Press
DOI: 10.1016/j.cell.2019.04.030

Mechanochemical Feedback Loops in Development and Disease

Author(s): Edouard Hannezo, Carl-Philipp Heisenberg
Published in: Cell, Issue 178/1, 2019, Page(s) 12-25, ISSN 0092-8674
Publisher: Cell Press
DOI: 10.1016/j.cell.2019.05.052

Light-activated Frizzled7 reveals a permissive role of non-canonical wnt signaling in mesendoderm cell migration

Author(s): Daniel Čapek, Michael Smutny, Alexandra-Madelaine Tichy, Maurizio Morri, Harald Janovjak, Carl-Philipp Heisenberg
Published in: eLife, Issue 8, 2019, ISSN 2050-084X
Publisher: eLife Sciences Publications
DOI: 10.7554/elife.42093

Tissue rheology in embryonic organization

Author(s): Nicoletta I Petridou, Carl‐Philipp Heisenberg
Published in: The EMBO Journal, Issue 38/20, 2019, ISSN 0261-4189
Publisher: Nature Publishing Group
DOI: 10.15252/embj.2019102497

Mechanosensation of Tight Junctions Depends on ZO-1 Phase Separation and Flow

Author(s): Cornelia Schwayer, Shayan Shamipour, Kornelija Pranjic-Ferscha, Alexandra Schauer, Maria Balda, Masazumi Tada, Karl Matter, Carl-Philipp Heisenberg
Published in: Cell, Issue 179/4, 2019, Page(s) 937-952.e18, ISSN 0092-8674
Publisher: Cell Press
DOI: 10.1016/j.cell.2019.10.006

Rigidity percolation uncovers a structural basis for embryonic tissue phase transitions.

Author(s): Nicoletta I. Petridou; Bernat Corominas-Murtra; Carl-Philipp Heisenberg; Edouard Hannezo
Published in: Cell, Issue 00928674, 2021, Page(s) 1914–1928, ISSN 0092-8674
Publisher: Cell Press
DOI: 10.1016/j.cell.2021.02.017

Zebrafish embryonic explants undergo genetically encoded self-assembly.

Author(s): Alexandra Schauer; Diana Pinheiro; Robert Hauschild; Carl-Philipp Heisenberg
Published in: eLife, Issue 2050084X, 2020, ISSN 2050-084X
Publisher: eLife Sciences Publications
DOI: 10.7554/elife.55190

Book chapters (1)

Zebrafish gastrulation: Putting fate in motion

Author(s): Diana Pinheiro, Carl-Philipp Heisenberg
Published in: Gastrulation: From Embryonic Pattern to Form, Issue 136, 2020, Page(s) 343-375, ISBN 9780-128127988
Publisher: Elsevier
DOI: 10.1016/bs.ctdb.2019.10.009