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Single-cell temporal tracking of epigenetic DNA marks

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Publications

Methyltransferase-directed orthogonal tagging and sequencing of miRNAs and bacterial small RNAs

Author(s): Milda Mickutė, Kotryna Kvederavičiūtė, Aleksandr Osipenko, Raminta Mineikaitė, Saulius Klimašauskas, Giedrius Vilkaitis
Published in: BMC Biology, 19/1, 2021, Page(s) 129, ISSN 1741-7007
Publisher: BioMed Central
DOI: 10.1186/s12915-021-01053-w

Enzymatic hydroxylation and excision of extended 5-methylcytosine analogues

Author(s): Miglė Tomkuvienė, Diana Ikasalaitė, Anton Slyvka, Audronė Rukšėnaitė, Mirunalini Ravichandran, Tomasz P. Jurkowski, Matthias Bochtler, Saulius Klimašauskas
Published in: Journal of Molecular Biology, 423, 2020, Page(s) 6157-6167, ISSN 0022-2836
Publisher: Academic Press
DOI: 10.1016/j.jmb.2020.10.011

Selective chemical tracking of Dnmt1 catalytic activity in live cells.

Author(s): V. Stankevičius, P. Gibas, B. Masiulionytė, L. Gasiulė, V. Masevičius, S. Klimašauskas, G. Vilkaitis
Published in: Molecular Cell, 82, 2022, Page(s) 1053-1065, ISSN 1097-2765
Publisher: Cell Press
DOI: 10.1016/j.molcel.2022.02.008

Alleviation of C⋅C Mismatches in DNA by the Escherichia coli Fpg Protein

Author(s): Almaz Nigatu Tesfahun, Marina Alexeeva, Miglė Tomkuvienė, Aysha Arshad, Prashanna Guragain, Arne Klungland, Saulius Klimašauskas, Peter Ruoff, Svein Bjelland
Published in: Frontiers in Microbiology, 12, 2021, Page(s) 608839, ISSN 1664-302X
Publisher: Frontiers Media
DOI: 10.3389/fmicb.2021.608839

Distribution and regulatory roles of oxidized 5-methylcytosines in DNA and RNA of the Basidiomycete fungi Laccaria bicolor and Coprinopsis cinerea.

Author(s): J. Ličytė, K. Kvederavičiūtė, A. Rukšėnaitė, E. Godliauskaitė, P. Gibas, V. Tomkutė, G. Petraitytė, V. Masevičius, S. Klimašauskas, E. Kriukienė
Published in: Open Biology, 12, 2022, ISSN 2046-2441
Publisher: Royal Society Publishing
DOI: 10.1098/rsob.20160049

Repurposing enzymatic transferase reactions for targeted labeling and analysis of DNA and RNA

Author(s): Miglė Tomkuvienė, Milda Mickutė, Giedrius Vilkaitis, Saulius Klimašauskas
Published in: Current Opinion in Biotechnology, 55, 2019, Page(s) 114-123, ISSN 0958-1669
Publisher: Elsevier BV
DOI: 10.1016/j.copbio.2018.09.008

Animal Hen1 2′-O-methyltransferases as tools for 3′-terminal functionalization and labelling of single-stranded RNAs

Author(s): Milda Mickutė, Milda Nainytė, Lina Vasiliauskaitė, Alexandra Plotnikova, Viktoras Masevičius, Saulius Klimašauskas, Giedrius Vilkaitis
Published in: Nucleic Acids Research, 46/17, 2018, Page(s) e104-e104, ISSN 0305-1048
Publisher: Oxford University Press
DOI: 10.1093/nar/gky514

An Adversarial DNA N6-Methyladenine-Sensor Network Preserves Polycomb Silencing

Author(s): Soo-Mi Kweon, Yibu Chen, Eugene Moon, Kotryna Kvederaviciutė, Saulius Klimasauskas, Douglas E. Feldman
Published in: Molecular Cell, 74, 2019, Page(s) 1138-1147.e6, ISSN 1097-2765
Publisher: Cell Press
DOI: 10.1016/j.molcel.2019.03.018

Precise genomic mapping of 5-hydroxymethylcytosine via covalent tether-directed sequencing

Author(s): Povilas Gibas, Milda Narmontė, Zdislav Staševskij, Juozas Gordevičius, Saulius Klimašauskas, Edita Kriukienė
Published in: PLOS Biology, 18, 2020, Page(s) e3000684, ISSN 1544-9173
Publisher: Public Library of Science
DOI: 10.1371/journal.pbio.3000684

Enhanced nucleosome assembly at CpG sites containing an extended 5-methylcytosine analogue

Author(s): Miglė Tomkuvienė, Markus Meier, Diana Ikasalaitė, Julia Wildenauer, Visvaldas Kairys, Saulius Klimašauskas, Laura Manelytė
Published in: Nucleic Acids Research, 50, 2022, ISSN 0305-1048
Publisher: Oxford University Press
DOI: 10.1093/nar/gkac444

FANCD2 maintains replication fork stability during misincorporation of the DNA demethylation products 5-hydroxymethyl-2’-deoxycytidine and 5-hydroxymethyl-2’-deoxyuridine.

Author(s): María José Peña-Gómez, Paula Moreno-Gordillo, Milda Narmontė, Clara B. García-Calderón, Audronė Rukšėnaitė, Saulius Klimašauskas, Iván V. Rosado
Published in: Cell Death & Disease, 13/5, 2022, Page(s) 503, ISSN 2041-4889
Publisher: Nature Publishing Group
DOI: 10.1038/s41419-022-04952-0

Meet the author: Vaidotas Stankevičius, Giedrius Vilkaitis, and Saulius Klimašauskas

Author(s): Vaidotas Stankevičius, Giedrius Vilkaitis, and Saulius Klimašauskas
Published in: Molecular Cell, 82/5, 2022, Page(s) 879-881, ISSN 1097-2765
Publisher: Cell Press
DOI: 10.1016/j.molcel.2022.02.019