Catalytic Dual-Function Devices Against Cancer

Publicaciones

Glutathione-triggered catalytic response of copper-iron mixed oxide nanoparticles. Leveraging tumor microenvironment conditions for chemodynamic therapy

Autores: Javier Bonet-Aletá, María Sancho-Albero, Javier Calzada-Funes, Silvia Irusta, Pilar Martín-Duque, José L. Hueso, Jesús Santamaría
Publicado en: Journal of Colloid and Interface Science, Edición 617 (2022), 2022, Página(s) 704-717, ISSN 1095-7103
Editor: Elsevier
DOI: 10.1016/j.jcis.2022.03.036

Laser-induced tuning of carbon nanosensitizers to maximize nitrogen doping and reactive oxygen species production in the visible range

Autores: Ainhoa Madrid, Gema Martínez, Felipe Hornos, Javier Bonet-Aletá, Esteban Calvo, Antonio Lozano, Jose L. Hueso
Publicado en: Catalysis Today, Edición 422, 2023, Página(s) 114214, ISSN 0920-5861
Editor: Elsevier BV
DOI: 10.1016/j.cattod.2023.114214

Superfluorinated extracellular vesicles for in vivo imaging by 19F-MRI

Autores: María Sancho-Albero, Nazeeha Ayaz, Victor Sebastian, Cristina Chirizzi, Miguel Encinas-Gimenez, Giulia Neri, Linda Chaabane, Lluís Luján, Pilar Martin-Duque, Pierangelo Metrangolo, Jesús Santamaría, Francesca Baldelli Bombelli
Publicado en: ACS Applied Materials and Interfaces, Edición 15, 7, 2023, Página(s) 8974–8985, ISSN 1944-8252
Editor: American Chemical Society
DOI: 10.1021/acsami.2c20566

Extracellular vesicles-mediated bio-orthogonal catalysis in growing tumors

Autores: María Sancho-Albero,Víctor Sebastián, Ana M. Pérez-López, Pilar Martín-Duque, Asier Unciti-Broceta, Jesús Santamaría
Publicado en: Cells, Edición 13(8), 2024, Página(s) 691, ISSN 2073-4409
Editor: MPDI
DOI: 10.3390/cells13080691

Exosomes loaded with ultrasmall Pt nanoparticles: a novel low-toxicity alternative to cisplatin

Autores: María Sancho-Albero, Ana Martín-Pardillos, Lluís Lujan, Víctor Sebastián, Jesús Santamaría, Pilar Martín-Duque
Publicado en: Journal of Nanobiotechnology, Edición 20,1,473, 2022, ISSN 1477-3155
Editor: BioMed Central
DOI: 10.1186/s12951-022-01675-4

Covalent Cross-Linking of 2H-MoS2 Nanosheets.

Autores: Manuel Vázquez Sulleiro; Ramiro Quirós‐Ovies; Mariano Vera-Hidalgo; I. Jénnifer Gómez; Victor Sebastian; Victor Sebastian; Jesus Santamaria; Jesus Santamaria; Jesus Santamaria; Emilio M. Pérez
Publicado en: Chemistry: A European Journal, Edición 27, 2020, Página(s) 2993-2996, ISSN 0947-6539
Editor: John Wiley & Sons Ltd.
DOI: 10.1002/chem.202004366

Unveiling the interplay between homogeneous and heterogeneous catalytic mechanisms in copper–iron nanoparticles working under chemically relevant tumour conditions

Autores: Javier Bonet-Aleta; Miguel Encinas-Gimenez; Esteban Urriolabeitia; Pilar Martin-Duque; Jose L. Hueso; Jesus Santamaria
Publicado en: Chemical Science, Edición 20416520, 2022, Página(s) 8307, ISSN 2041-6520
Editor: Royal Society of Chemistry
DOI: 10.1039/d2sc01379g

Bioorthogonal Uncaging of Cytotoxic Paclitaxel through Pd Nanosheet–Hydrogel Frameworks

Autores: Ana M. Pérez-López, Belén Rubio-Ruiz, Teresa Valero, Rafael Contreras-Montoya, Luis Álvarez de Cienfuegos, Víctor Sebastián, Jesús Santamaría, Asier Unciti-Broceta
Publicado en: Journal of Medicinal Chemistry, Edición 63/17, 2020, Página(s) 9650-9659, ISSN 0022-2623
Editor: American Chemical Society
DOI: 10.1021/acs.jmedchem.0c00781

Engineered nanostructured photocatalysts for cancer therapy

Autores: J. Bonet-Aletá, J.I. García-Peiró, J.L. Hueso
Publicado en: Catalysts, Edición 12, 2022, Página(s) 167, ISSN 2073-4344
Editor: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/catal12020167

Extracellular matrix density regulates the formation of tumour spheroids through cell migration

Autores: Inês G. Gonçalves, Jose Manuel Garcia-Aznar
Publicado en: PLOS Computational Biology, Edición 17/2, 2021, Página(s) e1008764, ISSN 1553-7358
Editor: PUBLIC LIBRARY SCIENCE
DOI: 10.1371/journal.pcbi.1008764

Nondestructive production of exosomes loaded with ultrathin palladium nanosheets for targeted bio-orthogonal catalysis

Autores: Victor Sebastian; Victor Sebastian; María Sancho-Albero; María Sancho-Albero; Manuel Arruebo; Manuel Arruebo; Ana M. Pérez-López; Ana M. Pérez-López; Belén Rubio-Ruiz; Belén Rubio-Ruiz; Pilar Martín-Duque; Asier Unciti-Broceta; Jesus Santamaria; Jesus Santamaria
Publicado en: Nature Protocols, Edición 16, 2020, Página(s) 131-163, ISSN 1754-2189
Editor: Nature Publishing Group
DOI: 10.1038/s41596-020-00406-z

Isolation of exosomes from whole blood by a new microfluidic device: proof of concept application in the diagnosis and monitoring of pancreatic cancer

Autores: María Sancho-Albero, Víctor Sebastián, Javier Sesé, Roberto Pazo-Cid, Gracia Mendoza, Manuel Arruebo, Pilar Martín-Duque, Jesús Santamaría
Publicado en: Journal of Nanobiotechnology, Edición 18/1, 2020, Página(s) ., ISSN 1477-3155
Editor: BioMed Central
DOI: 10.1186/s12951-020-00701-7

Platinum-based nanodendrites as glucose oxidase-mimicking surrogates

Autores: José I. García-Peiro, Javier Bonet-Aletá, María L. Tamayo-Fraile, José L. Hueso, Jesús Santamaría
Publicado en: Nanoscale, 2023, ISSN 2040-3364
Editor: Royal Society of Chemistry
DOI: 10.1039/d3nr02026f

Cellular Alterations Due to Direct and Indirect Interaction of Nanomaterials with Nucleic Acids

Autores: Encinas-Gimenez, Miguel; Martin-Duque, Pilar; Martín-Pardillos, Ana
Publicado en: International Journal of Molecular Sciences, Edición 25 (4), 2024, Página(s) 1983, ISSN 1422-0067
Editor: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms25041983

Recent advances in the design and photocatalytic enhanced performance of gold plasmonic nanostructures decorated with non-titania based semiconductor hetero-nanoarchitectures.

Autores: J.I. García-Peiró, J. Bonet-Aleta, C.J. Bueno-Alejo, J.L.Hueso.
Publicado en: Catalysts, Edición Volume 10, Edición 12, December 2020, Article number 1459, 2020, Página(s) 1-27, ISSN 2073-4344
Editor: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/catal10121459

Nitrogen-doped carbon nanodots deposited on titania nanoparticles: Unconventional near-infrared active photocatalysts for cancer therapy

Autores: Ainhoa Madrid, Ana Martín-Pardillos, Javier Bonet-Aletá. Maria Sancho-Albero, Gema Martinez, Javier Calzada-Funes, Pilar Martín-Duque, Jesús Santamaría, José L. Hueso
Publicado en: Catalysis Today, Edición Volume 4191, article 114154, 2023, ISSN 0920-5861
Editor: Elsevier BV
DOI: 10.1016/j.cattod.2023.114154

Transfer of photothermal nanoparticles using stem cell derived small extracellular vesicles for in vivo treatment of primary and multinodular tumours

Autores: María Sancho-Albero, Miguel Encinas-Giménez, Víctor Sebastián, Estela Pérez, Lluís Luján, Jesús Santamaría, Pilar Martín-Duque
Publicado en: Journal of Extracellular Vesicles, Edición 11, 2022, Página(s) 12193, ISSN 2001-3078
Editor: The International Society for Extracellular Vesicles
DOI: 10.1002/jev2.12193

Microwave-Driven Exfoliation of Bulk 2H-MoS<sub>2</sub> after Acetonitrile Prewetting Produces Large-Area Ultrathin Flakes with Exceptionally High Yield

Autores: Ramiro Quirós-Ovies; María Laborda; Natalia Martín Sabanés; Lucía Martín-Pérez; Sara Moreno-Da Silva; Enrique Burzurí; Víctor Sebastian; Emilio M. Pérez; Jesús Santamaría
Publicado en: ACS Nano, Edición Volume 17, Edición 6, 2023, Página(s) 5984-5993, ISSN 1936-0851
Editor: American Chemical Society
DOI: 10.1021/acsnano.3c00280

In Cellulo Bioorthogonal Catalysis by Encapsulated AuPd Nanoalloys. Overcoming Intracellular Deactivation

Autores: Belén Rubio-Ruiz; Ana M. Pérez-López; Laura Uson; M. Carmen Ortega-Liebana; Teresa Valero; Manuel Arruebo; Jose L. Hueso; Victor Sebastian; Jesus Santamaria; Asier Unciti-Broceta
Publicado en: Rubio Ruiz , B , Perez-Lopez , A , Uson , L , Ortega Liebana , M C , Valero , T , Arruebo , M , Hueso , J L , Sebastian , V , Santamaría , J & Unciti-Broceta , A 2023 , ' In Cellulo Bioorthogonal Catalysis by Encapsulated AuPd Nanoalloys. Overcoming Intracellular Deactivation ' , Nano Letters . https://doi.org/10.1021/acs.nanolett.2c03593, Edición 23, 3, 2023, Página(s) 804–811, ISSN 1530-6984
Editor: American Chemical Society
DOI: 10.1021/acs.nanolett.2c03593

High-performance thin-layer chromatography-densitometry-tandem ESI-MS to evaluate phospholipid content in exosomes of cancer cells

Autores: María Sancho-Albero, Carmen Jarne, María Savirón, Pilar Martín-Duque, Luis Membrado, Vicente L. Cebolla, Jesús Santamaría
Publicado en: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, Edición Volume 23, Edición 3, 2022, Página(s) 1150, ISSN 1422-0067
Editor: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms23031150

Nanoparticle-Catalyzed Transamination under Tumor Microenvironment Conditions: A Novel Tool to Disrupt the Pool of Amino Acids and GSSG in Cancer Cells

Autores: Javier Bonet-Aleta; Juan Vicente Alegre-Requena; Javier Martin-Martin; Miguel Encinas-Gimenez; Ana Martín-Pardillos; Pilar Martin-Duque; Jose L. Hueso; Jesus Santamaria
Publicado en: Nano Letters, Edición 24, 14, 2024, Página(s) 4091–4100, ISSN 1530-6984
Editor: American Chemical Society
DOI: 10.1021/acs.nanolett.3c04947

Exosome origin determines cell targeting and the transfer of therapeutic nanoparticles towards target cells

Autores: María Sancho-Albero, Nuria Navascués, Gracia Mendoza, Víctor Sebastián, Manuel Arruebo, Pilar Martín-Duque, Jesús Santamaría
Publicado en: Journal of Nanobiotechnology, Edición 17/1, 2019, Página(s) ., ISSN 1477-3155
Editor: BioMed Central
DOI: 10.1186/s12951-018-0437-z

Luminescent mesoporous nanorods as photocatalytic enzyme-like peroxidase surrogates

Autores: M. Carmen Ortega-Liebana, Jose L. Hueso, Rodrigo Fernandez-Pacheco, Silvia Irusta, Jesus Santamaria
Publicado en: Chemical Science, Edición 9/40, 2018, Página(s) 7766-7778, ISSN 2041-6520
Editor: Royal Society of Chemistry
DOI: 10.1039/c8sc03112f

Upconverting Carbon Nanodots from Ethylenediaminetetraacetic Acid (EDTA) as Near‐Infrared Activated Phototheranostic Agents

Autores: M. Carmen Ortega‐Liebana, M. Mar Encabo‐Berzosa, Alvaro Casanova, M. Desiree Pereboom, J. Octavio Alda, Jose L. Hueso, Jesus Santamaria
Publicado en: Chemistry – A European Journal, Edición 25/21, 2019, Página(s) 5539-5546, ISSN 0947-6539
Editor: John Wiley & Sons Ltd.
DOI: 10.1002/chem.201806307

In-Situ Deposition of Plasmonic Gold Nanotriangles and Nanoprisms onto Layered Hydroxides for Full-Range Photocatalytic Response towards the Selective Reduction of p-Nitrophenol

Autores: Javier Graus, Carlos Bueno-Alejo, Jose Hueso
Publicado en: Catalysts, Edición 8/9, 2018, Página(s) 354, ISSN 2073-4344
Editor: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/catal8090354

Triangular and Prism-Shaped Gold-Zinc Oxide Plasmonic Nanostructures: In situ Reduction, Assembly, and Full-Range Photocatalytic Performance

Autores: Bruno Bottega-Pergher, Javier Graus, Carlos J. Bueno-Alejo, Jose L. Hueso
Publicado en: European Journal of Inorganic Chemistry, Edición 2019/27, 2019, Página(s) 3228-3234, ISSN 1434-1948
Editor: John Wiley & Sons Ltd.
DOI: 10.1002/ejic.201900213

Efficient encapsulation of theranostic nanoparticles in cell-derived exosomes: leveraging the exosomal biogenesis pathway to obtain hollow gold nanoparticle-hybrids

Autores: María Sancho-Albero, Maria del Mar Encabo-Berzosa, Manuel Beltrán-Visiedo, Lola Fernández-Messina, Víctor Sebastián, Francisco Sánchez-Madrid, Manuel Arruebo, Jesús Santamaría, Pilar Martín-Duque
Publicado en: Nanoscale, Edición 11/40, 2019, Página(s) 18825-18836, ISSN 2040-3364
Editor: Royal Society of Chemistry
DOI: 10.1039/c9nr06183e

Cancer-derived exosomes loaded with ultrathin palladium nanosheets for targeted bioorthogonal catalysis

Autores: María Sancho-Albero, Belén Rubio-Ruiz, Ana M. Pérez-López, Víctor Sebastián, Pilar Martín-Duque, Manuel Arruebo, Jesús Santamaría, Asier Unciti-Broceta
Publicado en: Nature Catalysis, Edición 2/10, 2019, Página(s) 864-872, ISSN 2520-1158
Editor: Nature
DOI: 10.1038/s41929-019-0333-4

Laser-driven direct synthesis of carbon nanodots and application as sensitizers for visible-light photocatalysis

Autores: Nuria Mas, Jose L. Hueso, Gema Martinez, Ainhoa Madrid, Reyes Mallada, M. Carmen Ortega-Liebana, Carlos Bueno-Alejo, Jesus Santamaria
Publicado en: Carbon, Edición 156, 2020, Página(s) 453-462, ISSN 0008-6223
Editor: Pergamon Press Ltd.
DOI: 10.1016/j.carbon.2019.09.073

Silver-Copper Oxide Heteronanostructures for the Plasmonic-Enhanced Photocatalytic Oxidation of N-Hexane in the Visible-NIR Range

Autores: Hugo Suarez, Adrian Ramirez, Carlos J. Bueno-Alejo, Jose L. Hueso
Publicado en: Materials, Edición 12/23, 2019, Página(s) 3858, ISSN 1996-1944
Editor: MDPI Open Access Publishing
DOI: 10.3390/ma12233858

Gold-Based Nanoparticles on Amino-Functionalized Mesoporous Silica Supports as Nanozymes for Glucose Oxidation

Autores: M. Carmen Ortega-Liebana, Javier Bonet-Aleta, Jose L. Hueso, Jesus Santamaria
Publicado en: Catalysts, Edición 10/3, 2020, Página(s) 333, ISSN 2073-4344
Editor: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/catal10030333

Controlled Covalent Functionalization of 2H‐MoS2 with Molecular or Polymeric Adlayers.

Autores: Ramiro Quirós-Ovies, Manuel Vázquez Sulleiro, Mariano Vera-Hidalgo, Javier Prieto, I. Jénnifer Gómez, Víctor Sebastián, Jesús Santamaría, Emilio M. Pérez
Publicado en: Chemistry – A European Journal, Edición 26, 2020, Página(s) 1-7, ISSN 0947-6539
Editor: John Wiley & Sons Ltd.
DOI: 10.1002/chem.202000068

Use of exosomes as vectors to carry advanced therapies

Autores: María Sancho-Albero, Ana Medel-Martínez, Pilar Martín-Duque
Publicado en: RSC Advances, Edición 10/40, 2020, Página(s) 23975-23987, ISSN 2046-2069
Editor: Royal Society of Chemistry
DOI: 10.1039/d0ra02414g

X-ray Photoelectron Spectroscopy (XPS) Analysis of Nitrogen Environment in Small Extracellular Vesicle Membranes: A Potential Novel Technique with Application for Cancer Screening

Autores: María Sancho-Albero; Ana Martín-Pardillos; Silvia Irusta; Víctor Sebastián; Vicente Luis Cebolla; Roberto Pazo-Cid; Pilar Martín-Duque; Jesús Santamaría
Publicado en: Cancers, Edición Volume 15; Edición 9, 2023, Página(s) 2479, ISSN 2072-6694
Editor: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/cancers15092479

Manganese oxide nano-platforms in cancer therapy: Recent advances on the development of synergistic strategies targeting the tumor microenvironment

Autores: Bonet-Aletá, Javier; Calzada-Funes, Javier; Hueso, José L.
Publicado en: Applied Materials Today, Edición 23529407, 2022, Página(s) 101628, ISSN 2352-9407
Editor: Elsevier
DOI: 10.1016/j.apmt.2022.101628

Fluid flow to mimic organ function in 3D <i>in vitro</i> models

Autores: Yago Juste-Lanas; Silvia Hervas-Raluy; José Manuel García-Aznar; Alejandra González-Loyola
Publicado en: APL Bionengineering, Edición 7, 2023, Página(s) 031501, ISSN 2473-2877
Editor: AIP Publishing
DOI: 10.1063/5.0146000

Small Warriors of Nature: Novel Red Emissive Chlorophyllin Carbon Dots Harnessing Fenton‐Fueled Ferroptosis for In Vitro and In Vivo Cancer Treatment

Autores: Emel Kirbas Cilingir; Omur Besbinar; Linda Giro; Mattia Bartoli; Jose L. Hueso; Keenan J. Mintz; Yagmur Aydogan; Jordan M. Garber; Mine Turktas; Okan Ekim; Ahmet Ceylan; Mehmet Altay Unal; Mine Ensoy; Fikret Arı; Ozge Ozgenç Çinar; Berfin Ilayda Ozturk; Cemile Gokce; Demet Cansaran‐Duman; Markus Braun; Josef Wachtveitl; Jesus Santamaria; Lucia Gemma Delogu; Alberto Tagliaferro; Açelya Yilmaz
Publicado en: Small, Edición 20, 2024, Página(s) 2309283, ISSN 1613-6810
Editor: Wiley - V C H Verlag GmbbH & Co.
DOI: 10.1002/smll.202309283

Gold-platinum nanoparticles with core-shell configuration as efficient oxidase-like nanosensors for glutathione detection

Autores: Javier Bonet-Aletá, José I. García-Peiró, Silvia Irusta, José L. Hueso
Publicado en: Nanomaterials, Edición 12 (5), 2022, Página(s) 755, ISSN 2079-4991
Editor: MDPI
DOI: 10.3390/nano12050755

Heterogeneous-driven glutathione oxidation: Defining the catalytic role of chalcopyrite nanoparticles

Autores: Leticia Sánchez-Uriel, Javier Bonet-Aletá, Alfonso Ibarra, José L. Hueso
Publicado en: Journal of Physical Chemistry C, Edición C 2023, 127, 29, 2023, Página(s) 14146–14154, ISSN 1932-7447
Editor: American Chemical Society
DOI: 10.1021/acs.jpcc.3c00987

Cellular alterations in carbohydrate and lipid metabolism due to interactions with nanomaterials

Autores: Ana Martín-Pardillos, Pilar Martín-Duque
Publicado en: J. Funct. Biomater, Edición 14(5), 2023, Página(s) 274, ISSN 2079-4983
Editor: MDPI
DOI: 10.3390/jfb14050274

Enzyme-iron oxide nanoassemblies: A review of immobilization and biocatalytic applications

Autores: Ángeles Valls-Chivas, Javier Gómez, José I. García-Peiro, Felipes Hornos, José L. Hueso
Publicado en: Catalysts, Edición 13(6), 2023, Página(s) 980, ISSN 2073-4344
Editor: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/catal13060980

Anisotropic Au-ZnO photocatalyst for the visible-light expanded oxidation of n-hexane

Autores: Carlos J. Bueno-Alejo, Javier Graus, Raul Arenal, Marta Lafuente, Bruno Bottega-Pergher, Jose L. Hueso
Publicado en: Catalysis Today, Edición In press, corrected proof, 2020, Página(s) In press, corrected proof, ISSN 0920-5861
Editor: Elsevier BV
DOI: 10.1016/j.cattod.2020.03.063

Synergistic assembly of gold and copper-iron oxide nanocatalysts to promote the simultaneous depletion of glucose and glutathione

Autores: J. Bonet-Aletá, J.L. Hueso, L. Sánchez-Uriel, M. Encinas-Giménez, S. Irusta, P. Martin-Duque, G. Martínez, J. Santamaría
Publicado en: Materials Today Chemistry, Edición 29 (2023), 2023, Página(s) 101404, ISSN 2468-5194
Editor: Elsevier
DOI: 10.1016/j.mtchem.2023.101404

Targeting glutathione with copper-iron based nanoplatforms for cancer therapy: homgeneous and heterogeneous catalytic interplay in the tumor microenvironment

Autores: Bonet-Aleta, Javier; Encinas-Giménez, Miguel; Urriolabeitia, Esteban P.; Martín-Duque, Pilar; Hueso, José L.; Santamaría, Jesús
Publicado en: XXXVIII Reunión Bienal de la Real Sociedad Española de Química (2022), Edición 3, 2022
Editor: XXXVIII Reunión Bienal de la Real Sociedad Española de Química (2022)

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