Chiral Morphogenesis - Physical Mechanisms of Actomyosin-Based Left/Right Symmetry Breaking in Biological Systems

Project Information

CHIMO

Grant agreement ID: 742712

DOI 10.3030/742712

Project closed

EC signature date 31 May 2017

Start date 1 January 2018

End date 31 March 2024

Funded under

• EXCELLENT SCIENCE - European Research Council (ERC)

Total cost € 2 500 000,00

EU contribution € 2 500 000,00

Coordinated by

TECHNISCHE UNIVERSITAET DRESDEN
Germany

Publications

Peer reviewed articles (8)

Aurora A depletion reveals centrosome-independent polarization mechanism in Caenorhabditis elegans

Author(s): Kerstin Klinkert, Nicolas Levernier, Peter Gross, Christian Gentili, Lukas von Tobel, Marie Pierron, Coralie Busso, Sarah Herrman, Stephan W Grill, Karsten Kruse, Pierre Gönczy
Published in: eLife, Issue 8, 2019, ISSN 2050-084X
Publisher: eLife Sciences Publications
DOI: 10.7554/eLife.44552

Orchestrating nonmuscle myosin II filament assembly at the onset of cytokinesis

Author(s): Fereshteh R. Najafabadi, Mark Leaver, and Stephan W. Grill
Published in: MOLECULAR BIOLOGY OF THE CELL, Issue 10591524, 2022, ISSN 1059-1524
Publisher: American Society for Cell Biology
DOI: 10.1091/mbc.e21-12-0599

Guiding self-organized pattern formation in cell polarity establishment

Author(s): Peter Gross, K. Vijay Kumar, Nathan W. Goehring, Justin S. Bois, Carsten Hoege, Frank Jülicher, Stephan W. Grill
Published in: Nature Physics, Issue 15/3, 2019, Page(s) 293-300, ISSN 1745-2473
Publisher: Nature Publishing Group
DOI: 10.1038/s41567-018-0358-7

Morphogenetic degeneracies in the actomyosin cortex

Author(s): Sundar Ram Naganathan, Sebastian Fürthauer, Josana Rodriguez, Bruno Thomas Fievet, Frank Jülicher, Julie Ahringer, Carlo Vittorio Cannistraci, Stephan W Grill
Published in: eLife, Issue 7, 2018, ISSN 2050-084X
Publisher: eLife Sciences Publications
DOI: 10.7554/elife.37677

Cell lineage-dependent chiral actomyosin flows drive cellular rearrangements in early Caenorhabditis elegans development

Author(s): Lokesh G Pimpale, Teije C Middelkoop, Alexander Mietke, Stephan W Grill
Published in: eLife, Issue 9, 2020, ISSN 2050-084X
Publisher: eLife Sciences Publications
DOI: 10.7554/elife.54930

A condensate dynamic instability orchestrates actomyosin cortex activation

Author(s): Victoria Tianjing Yan, Arjun Narayanan, Frank Jülicher, Stephan W. Grill
Published in: Nature, Issue 00280836, 2022, Page(s) 597–604, ISSN 0028-0836
Publisher: Nature Publishing Group
DOI: 10.1038/s41586-022-05084-3

CYK-1/Formin activation in cortical RhoA signaling centers promotes organismal left–right symmetry breaking

Author(s): Teije C Middelkoop, Júlia Garcia-Baucells, Porfirio Quintero-Cadena, Lokesh G Pimpale, Shahrzad Yazdi, Paul W Sternberg, Peter Gross, Stephan W Grill
Published in: Proceedings of the National Academy of Sciences (PNAS), Issue 00278424, 2021, Page(s) 118, ISSN 0027-8424
Publisher: National Academy of Sciences
DOI: 10.1073/pnas.2021814118

Attachment of the blastoderm to the vitelline envelope affects gastrulation of insects

Author(s): Stefan Münster, Akanksha Jain, Alexander Mietke, Anastasios Pavlopoulos, Stephan W. Grill, Pavel Tomancak
Published in: Nature, Issue 568/7752, 2019, Page(s) 395-399, ISSN 0028-0836
Publisher: Nature Publishing Group
DOI: 10.1038/s41586-019-1044-3