Endogenous barcoding for in vivo fate mapping of lineage development in the blood and immune system

Project Information

BARCODED-CELLTRACING

Grant agreement ID: 742883

DOI 10.3030/742883

Project closed

EC signature date 10 May 2017

Start date 1 July 2017

End date 30 June 2023

Funded under

• EXCELLENT SCIENCE - European Research Council (ERC)

Total cost € 2 500 000,00

EU contribution € 2 500 000,00

Coordinated by

DEUTSCHES KREBSFORSCHUNGSZENTRUM HEIDELBERG
Germany

Publications

Peer reviewed articles (9)

Runner's niche: multipurpose stromal cells maintained by exercise

Author(s): Nikolaus Dietlein; Hans-Reimer Rodewald
Published in: Trends in Immunology, Issue 42 (10), 2021, Page(s) 841-843, ISSN 1471-4906
Publisher: Elsevier BV
DOI: 10.1016/j.it.2021.08.007

Flt3- and Tie2-Cre tracing identifies regeneration in sepsis from multipotent progenitors but not hematopoietic stem cells

Author(s): Ann-Kathrin Fanti; Katrin Busch; Alessandro Greco; Xi Wang; Branko Cirovic; Fuwei Shang; Tamar Nizharadze; Larissa Frank; Melania Barile; Thorsten B. Feyerabend; Thomas Höfer; Hans-Reimer Rodewald
Published in: Cell Stem Cell, Issue 1, 2023, ISSN 1934-5909
Publisher: Cell Press
DOI: 10.1016/j.stem.2022.12.014

Toward the dissection of hematopoietic stem cell fates and their determinants.

Author(s): Fuwei Shang; Hans-Reimer Rodewald
Published in: Current Opinion in Genetics & Development, Issue 1, 2022, ISSN 0959-437X
Publisher: Elsevier BV
DOI: 10.1016/j.gde.2022.101945

Polylox barcoding reveals haematopoietic stem cell fates realized in vivo

Author(s): Weike Pei, Thorsten B. Feyerabend, Jens Rössler, Xi Wang, Daniel Postrach, Katrin Busch, Immanuel Rode, Kay Klapproth, Nikolaus Dietlein, Claudia Quedenau, Wei Chen, Sascha Sauer, Stephan Wolf, Thomas Höfer, Hans-Reimer Rodewald
Published in: Nature, Issue 548/7668, 2017, Page(s) 456-460, ISSN 0028-0836
Publisher: Nature Publishing Group
DOI: 10.1038/nature23653

Differentiation-based model of hematopoietic stem cell functions and lineage pathways

Author(s): Thomas Höfer, Hans-Reimer Rodewald
Published in: Blood, Issue 132/11, 2018, Page(s) 1106-1113, ISSN 0006-4971
Publisher: American Society of Hematology
DOI: 10.1182/blood-2018-03-791517

Using Cre-recombinase-driven Polylox barcoding for in vivo fate mapping in mice

Author(s): Weike Pei, Xi Wang, Jens Rössler, Thorsten B. Feyerabend, Thomas Höfer, Hans-Reimer Rodewald
Published in: Nature Protocols, Issue 14/6, 2019, Page(s) 1820-1840, ISSN 1754-2189
Publisher: Nature Publishing Group
DOI: 10.1038/s41596-019-0163-5

Do haematopoietic stem cells age?

Author(s): Kenneth Dorshkind, Thomas Höfer, Encarnacion Montecino-Rodriguez, Peter D. Pioli, Hans-Reimer Rodewald
Published in: Nature Reviews Immunology, Issue 20/3, 2020, Page(s) 196-202, ISSN 1474-1733
Publisher: Nature Publishing Group
DOI: 10.1038/s41577-019-0236-2

Resolving fate and transcriptome of hematopoietic stem cell clones

Author(s): Weike Pei; Fuwei Shang; Xi Wang; Ann-Kathrin Fanti; Alessandro Greco; Katrin Busch; Kay Klapproth; Qin Zhang; Claudia Quedenau; Sascha Sauer; Thorsten B. Feyerabend; Thomas Höfer; Hans-Reimer Rodewald
Published in: Cell Stem Cell, Issue 3, 2020, Page(s) 383-395, ISSN 1875-9777
Publisher: Elsevier
DOI: 10.1101/2020.03.25.008433

β2-adrenergic receptor–mediated negative regulation of group 2 innate lymphoid cell responses

Author(s): Moriyama, Saya; Brestoff, Jonathan R.; Flamar, Anne-Laure; Moeller, Jesper B.; Klose, Christoph S. N.; Rankin, Lucille C.; Yudanin, Naomi A.; Monticelli, Laurel A.; Putzel, Gregory Garbès; Rodewald, Hans-Reimer; Artis, David
Published in: Moriyama , S , Brestoff , J R , Flamar , A-L , Moeller , J B , Klose , C S N , Rankin , L C , Yudanin , N A , Monticelli , L A , Putzel , G G , Rodewald , H-R & Artis , D 2018 , ' β 2 -adrenergic receptor-mediated negative regulation of group 2 innate lymphoid cell responses ' , Science , vol. 359 , no. 6379 , pp. 1056-1061 . https://doi.org/10.1126/science.aan4829, Issue 359/6379, 2018, Page(s) 1056-1061, ISSN 1095-9203
Publisher: AAAS
DOI: 10.1126/science.aan4829