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Inherited disfunctions of brain microcirculation

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Publications

Fine-Tuning of Sox17 and Canonical Wnt Coordinates the Permeability Properties of the Blood-Brain Barrier

Author(s): Monica Corada, Fabrizio Orsenigo, Ganesh Parameshwar Bhat, Lei Liu Conze, Ferruccio Breviario, Sara Isabel Cunha, Lena Claesson-Welsh, Galina V. Beznoussenko, Alexander A. Mironov, Marco Bacigaluppi, Gianvito Martino, Mara E. Pitulescu, Ralf H. Adams, Peetra Magnusson, Elisabetta Dejana
Published in: Circulation Research, Issue 124/4, 2019, Page(s) 511-525, ISSN 0009-7330
DOI: 10.1161/circresaha.118.313316

Deregulated TGF-β/BMP Signaling in Vascular Malformations

Author(s): Sara I. Cunha, Peetra U. Magnusson, Elisabetta Dejana, Maria Grazia Lampugnani
Published in: Circulation Research, Issue 121/8, 2017, Page(s) 981-999, ISSN 0009-7330
DOI: 10.1161/circresaha.117.309930

VE-Cadherin–Mediated Epigenetic Regulation of Endothelial Gene Expression

Author(s): Marco F. Morini, Costanza Giampietro, Monica Corada, Federica Pisati, Elisa Lavarone, Sara I. Cunha, Lei L. Conze, Nicola O’Reilly, Dhira Joshi, Svend Kjaer, Roger George, Emma Nye, Anqi Ma, Jian Jin, Richard Mitter, Michela Lupia, Ugo Cavallaro, Diego Pasini, Dinis P. Calado, Elisabetta Dejana, Andrea Taddei
Published in: Circulation Research, Issue 122/2, 2018, Page(s) 231-245, ISSN 0009-7330
DOI: 10.1161/circresaha.117.312392

Endothelial β-Catenin Signaling Supports Postnatal Brain and Retinal Angiogenesis by Promoting Sprouting, Tip Cell Formation, and VEGFR (Vascular Endothelial Growth Factor Receptor) 2 Expression

Author(s): Agnieszka Martowicz, Marta Trusohamn, Nina Jensen, Joanna Wisniewska-Kruk, Monica Corada, Frank Chenfei Ning, Julianna Kele, Elisabetta Dejana, Daniel Nyqvist
Published in: Arteriosclerosis, Thrombosis, and Vascular Biology, Issue 39/11, 2019, Page(s) 2273-2288, ISSN 1079-5642
DOI: 10.1161/atvbaha.119.312749

Endothelial cell clonal expansion in the development of cerebral cavernous malformations

Author(s): Matteo Malinverno, Claudio Maderna, Abdallah Abu Taha, Monica Corada, Fabrizio Orsenigo, Mariaelena Valentino, Federica Pisati, Carmela Fusco, Paolo Graziano, Monica Giannotta, Qing Cissy Yu, Yi Arial Zeng, Maria Grazia Lampugnani, Peetra U. Magnusson, Elisabetta Dejana
Published in: Nature Communications, Issue 10/1, 2019, ISSN 2041-1723
DOI: 10.1038/s41467-019-10707-x

CDC42 Deletion Elicits Cerebral Vascular Malformations via Increased MEKK3-Dependent KLF4 Expression

Author(s): Marco Castro, Bàrbara Laviña, Koji Ando, Alberto Álvarez-Aznar, Abdallah Abu Taha, Cord Brakebusch, Elisabetta Dejana, Christer Betsholtz, Konstantin Gaengel
Published in: Circulation Research, Issue 124/8, 2019, Page(s) 1240-1252, ISSN 0009-7330
DOI: 10.1161/circresaha.118.314300