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Direct Pathway Cloning of Neglected Bacteria in the Hunt for Novel (Bio-)Chemistry


Direct Pathway Cloning Combined with Sequence- and Ligation-Independent Cloning for Fast Biosynthetic Gene Cluster Refactoring and Heterologous Expression

Autores: Paul M. D’Agostino, Tobias A. M. Gulder
Publicado en: ACS Synthetic Biology, 7/7, 2018, Page(s) 1702-1708, ISSN 2161-5063
Editor: American Chemical Society
DOI: 10.1021/acssynbio.8b00151

Direct pathway cloning of the sodorifen biosynthetic gene cluster and recombinant generation of its product in E. coli

Autores: Elke R. Duell, Paul M. D’Agostino, Nicole Shapiro, Tanja Woyke, Thilo M. Fuchs, Tobias A. M. Gulder
Publicado en: Microbial Cell Factories, 18/1, 2019, ISSN 1475-2859
Editor: BioMed Central
DOI: 10.1186/s12934-019-1080-6

Streptomyces sp. BV410 isolate from chamomile rhizosphere soil efficiently produces staurosporine with antifungal and antiangiogenic properties

Autores: Marija Mojicevic, Paul M. D'Agostino, Aleksandar Pavic, Sandra Vojnovic, Ramsankar Senthamaraikannan, Branka Vasiljevic, Tobias A. M. Gulder, Jasmina Nikodinovic‐Runic
Publicado en: MicrobiologyOpen, 9/3, 2020, ISSN 2045-8827
Editor: John Wiley and Sons Inc.
DOI: 10.1002/mbo3.986

Biosynthesis of cyanobacterin, a paradigm for furanolide core structure assembly

Autores: Paul M. D’Agostino, Catharina J. Seel, Xiaoqi Ji, Tanja Gulder & Tobias A. M. Gulder
Publicado en: Nature Chemical Biology, 15524450, 2022, Page(s) 652-658, ISSN 1552-4450
Editor: Nature Publishing Group
DOI: 10.1038/s41589-022-01013-7