Objective The aim of FISHODOR is to establish the identity of neural network components of the recently discovered tilapiareproductive pheromone. It will identify pheromone olfactory receptor(s) and their intracellular transduction pathways therebyincreasing our understanding of olfactory perception and signal integration of fish pheromones. The project will determinethe neuronal cell type (i.e. ciliated, microvillous or crypt-type olfactory receptor neurons) detecting the pheromone, it willestablish the transduction pathways (i.e. AC/cAMP or PLC/IP3) involved in its olfactory detection and will identify theolfactory receptor(s) that binds the pheromone. If enough time is available it will attempt to map the neuronal networkinvolved in the neuroendocrine response. The combination of electrophysiology, transcriptomics and molecular biology willbring high degree of novelty to explain the mechanism of action of olfactory receptor and neuronal signal integration. Fields of science natural sciencesbiological sciencesneurobiologynatural sciencesbiological scienceszoologyichthyologynatural sciencesbiological scienceszoologymammalogynatural sciencescomputer and information sciencesartificial intelligencecomputational intelligencenatural sciencesbiological sciencesmolecular biology Programme(s) H2020-EU.1.3. - EXCELLENT SCIENCE - Marie Skłodowska-Curie Actions Main Programme H2020-EU.1.3.2. - Nurturing excellence by means of cross-border and cross-sector mobility Topic(s) MSCA-IF-2016 - Individual Fellowships Call for proposal H2020-MSCA-IF-2016 See other projects for this call Funding Scheme MSCA-IF-EF-ST - Standard EF Coordinator CENTRO DE CIENCIAS DO MAR DO ALGARVE Net EU contribution € 160 635,60 Address Universidade do algarve 8005-139 Faro Portugal See on map Region Continente Algarve Algarve Activity type Research Organisations Links Contact the organisation Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 0,00
