Objective
Humans and the environment are simultaneously exposed to a plethora of pollutants. Nanomaterials (NMs) constitute a new class of substances with very particular physico-chemical properties whose use is steadily increasing a wide variety of products. Significant advances have been made in the field of NM toxicology, however most studies fail to consider the influence of NMs on the effects of other substances that co-exist in the environment and in particular the long term effects of these mixtures. In vitro approaches, particularly those allowing long term exposures as three dimensional (3D) cell cultures can generate essential information on the mechanisms underlying the toxicity of very low, environmentally realistic, concentrations of substances that only cause effects after long periods of exposure. The central objective of this proposal is to study the combined effects of NMs and pre-existing chemicals widely distributed in the environment using 3D cell cultures and long-term exposures to perform appropriate assessment of the effects associated with nanotechnology products. Achieving this outcome, the present project will provide an insight into the intracellular fate of NM, the transfer of NMs from cell to cell, and the effects of the combination of NM-organic substances. This information will support the safe and sustainable use of NMs as carriers of other substances (e.g. pesticides or antibiotics) in agriculture or livestock farming. This project addresses some important areas on the ecotoxicity of NMs declared as needed within the framework of REACH regulation. The topic of this project is directly related to the Social Challenges (agriculture, environment and health) and Industrial Leadership (nanotechnology) strategic policy objectives of Horizon 2020 programme. Moreover, the use of this experimental approach is requested under the call for “Science-based risk assessment and management of nanotechnologies” of the above mentioned work programme.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
- medical and health sciences basic medicine pharmacology and pharmacy pharmaceutical drugs antibiotics
- agricultural sciences agriculture, forestry, and fisheries agriculture
- agricultural sciences animal and dairy science domestic animals animal husbandry
- engineering and technology nanotechnology nano-materials
- medical and health sciences basic medicine toxicology
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Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
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H2020-EU.1.3. - EXCELLENT SCIENCE - Marie Skłodowska-Curie Actions
MAIN PROGRAMME
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H2020-EU.1.3.2. - Nurturing excellence by means of cross-border and cross-sector mobility
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Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
MSCA-IF-EF-ST - Standard EF
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Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
(opens in new window) H2020-MSCA-IF-2016
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Net EU financial contribution. The sum of money that the participant receives, deducted by the EU contribution to its linked third party. It considers the distribution of the EU financial contribution between direct beneficiaries of the project and other types of participants, like third-party participants.
28006 MADRID
Spain
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.