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Dissipative Self-Assembly: A powerful but unexplored tool to create temporary supramolecular hydrogels

Objective

The aim of this study is to develop molecular temporary hydrogels coupled to an energy dissipating chemical reaction (DisMolGels). Until now, most molecular self-assembled materials operate close to thermodynamic equilibrium, under static conditions, and are thus far from the interesting features biological living “materials” display. Biological materials are thermodynamically open and are kept far from equilibrium by a constant input of energy. This mode of self-assembly, one of the requirements of life, is referred to as dissipative or dynamic self-assembly. For this project I will focus on the recreation of part of such dissipative processes, and translating them to our current static hydrogel materials. With that, dynamic hydrogels with entirely new properties, most prominently their tunable lifetime and stiffness, will be developed. To do so, chemical fuels will be used as energy input and simple synthetic peptide derivatives will be constitute the self-assembling building blocks.
Not only will this project result in hydrogels with a tunable lifetime and stiffness, it also aims at setting new design guidelines and requirements to develop dynamic systems. Thereby it aims at aiding the scientific community as such rules currently lack, hampering the development of these interesting systems.
The ambitious research project builds on what I have already accomplished working on thermodynamically static self-assembled systems and the expertise that the host group offers in terms of dynamic materials approach. The research experience I will gain and all training received during the MSCA, will reinforce my expertise in this field and empower me to grow as an independent research leader.

Fields of science (EuroSciVoc)

CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.

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Programme(s)

Multi-annual funding programmes that define the EU’s priorities for research and innovation.

Topic(s)

Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.

Funding Scheme

Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.

MSCA-IF-EF-ST - Standard EF

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Call for proposal

Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.

(opens in new window) H2020-MSCA-IF-2016

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Coordinator

TECHNISCHE UNIVERSITAET MUENCHEN
Net EU contribution

Net EU financial contribution. The sum of money that the participant receives, deducted by the EU contribution to its linked third party. It considers the distribution of the EU financial contribution between direct beneficiaries of the project and other types of participants, like third-party participants.

€ 159 460,80
Address
Arcisstrasse 21
80333 Muenchen
Germany

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Region
Bayern Oberbayern München, Kreisfreie Stadt
Activity type
Higher or Secondary Education Establishments
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Total cost

The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.

€ 159 460,80
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