Objective
Transition-metal catalysed C-H activation is a powerful tool to functionalise and derivatize organic molecules at seemingly inert sites. The strategy opens new efficient synthetic routes to existing molecules and provides access to novel ones. Our aim is to develop palladium catalysed sp3 C-H activation technology for the synthesis of nitrogen heterocycles and for the derivatization of simple secondary amines to high value molecules. Our proposal will address demand in the pharmaceutical industry for the efficient synthesis of nitrogen-containing molecules to aid medicinal chemistry and accelerate the drug discovery processes.
Fields of science
- medical and health sciencesbasic medicinepharmacology and pharmacydrug discovery
- medical and health sciencesbasic medicinemedicinal chemistry
- natural scienceschemical sciencesinorganic chemistrytransition metals
- natural sciencesbiological sciencesbiochemistrybiomoleculesproteins
- natural scienceschemical sciencesorganic chemistryamines
Programme(s)
Funding Scheme
MSCA-IF-EF-ST - Standard EFCoordinator
THE CHANCELLOR MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE
Net EU contribution
€ 183 454,80
Address
TRINITY LANE THE OLD SCHOOLS
CB2 1TN Cambridge
United Kingdom
CB2 1TN Cambridge
United Kingdom
Region
East of England
East Anglia
Cambridgeshire CC
Activity type
Higher or Secondary Education Establishments
Links
Total cost
€ 183 454,80