Characterizing the clinical relevance and the mechanism underlying TRIB2-mediated drug resistance to MEK inhibitiors in the context of melanoma

Project Information

TRIBBLES

Grant agreement ID: 748585

DOI 10.3030/748585

Project closed

EC signature date 6 March 2017

Start date 1 September 2018

End date 31 August 2020

Funded under

• EXCELLENT SCIENCE - Marie Skłodowska-Curie Actions

Total cost € 160 635,60

EU contribution € 160 635,60

Coordinated by

UNIVERSIDADE DO ALGARVE
Portugal

Publications

Book chapters (2)

Monitoring the Transcriptional Activity of FOXO Transcription Factors by Analyzing their Target Genes

Author(s): Vanessa Henriques, Susana Machado, Wolfgang Link, Bibiana I. Ferreira
Published in: FOXO Transcription Factors - Methods and Protocols, Issue 1890, 2019, Page(s) 103-113, ISBN 978-1-4939-8899-0
Publisher: Springer New York
DOI: 10.1007/978-1-4939-8900-3_9

Image-based Identification of Chemical Compounds Capable of Trapping FOXO in the Cell Nucleus

Author(s): Susana Machado, Catarina Raposo, Bibiana I. Ferreira, Wolfgang Link
Published in: FOXO Transcription Factors - Methods and Protocols, Issue 1890, 2019, Page(s) 163-170, ISBN 978-1-4939-8899-0
Publisher: Springer New York
DOI: 10.1007/978-1-4939-8900-3_14

Peer reviewed articles (5)

The Emerging Therapeutic Landscape of Advanced Melanoma

Author(s): Vanessa Henriques, Teresa Martins, Wolfgang Link, Bibiana I. Ferreira
Published in: Current Pharmaceutical Design, Issue 24/5, 2018, Page(s) 549-558, ISSN 1381-6128
Publisher: Bentham Science Publishers
DOI: 10.2174/1381612824666180125093357

Tribbles Pseudokinases in Colorectal Cancer

Author(s): Bibiana I. Ferreira, Bruno Santos, Wolfgang Link, Ana Luísa De Sousa-Coelho
Published in: Cancers, Issue 13/11, 2021, Page(s) 2825, ISSN 2072-6694
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/cancers13112825

Small Molecule Inhibitors of CRM1

Author(s): Bibiana I. Ferreira, Bastien Cautain, Inês Grenho, Wolfgang Link
Published in: Frontiers in Pharmacology, Issue 11, 2020, ISSN 1663-9812
Publisher: Frontiers Media S.A.
DOI: 10.3389/fphar.2020.00625

CRISPR/Cas9‐mediated genome editing: From basic research to translational medicine

Author(s): Filipe V. Jacinto, Wolfgang Link, Bibiana I. Ferreira
Published in: Journal of Cellular and Molecular Medicine, Issue 24/7, 2020, Page(s) 3766-3778, ISSN 1582-1838
Publisher: Wiley-Blackwell
DOI: 10.1111/jcmm.14916

Harmine and Piperlongumine Revert TRIB2-Mediated Drug Resistance

Author(s): Susana Machado, Andreia Silva, Ana Luísa De Sousa-Coelho, Isabel Duarte, Inês Grenho, Bruno Santos, Victor Mayoral-Varo, Diego Megias, Fátima Sánchez-Cabo, Ana Dopazo, Bibiana I. Ferreira, Wolfgang Link
Published in: Cancers, Issue 12/12, 2020, Page(s) 3689, ISSN 2072-6694
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/cancers12123689

Thesis and dissertations (3)

CRISPR: applications in human pathologies and future prospects

Author(s): Author: Franco, Hannah Sabrina Advisor: Cancela, Leonor/ Ferreira, Bibiana
Published in: 2018
Publisher: Sapientia

Study of the TRIB2 protein network

Author(s): Author: Raposo, Catarina Martins Advisor: Link, Wolfgang / Ferreira, Bibiana
Published in: 2019
Publisher: Saptientia

Characterization of TRIB2-mediated resistance topharmacological inhibition of MEK

Author(s): Henriques VM, Link W, Ferreira BI.
Published in: 2017
Publisher: Sapientia - Universidade do Algarve