Characterizing the clinical relevance and the mechanism underlying TRIB2-mediated drug resistance to MEK inhibitiors in the context of melanoma

Project Information

TRIBBLES

Grant agreement ID: 748585

DOI

10.3030/748585

Project closed

EC signature date 6 March 2017

Start date 1 September 2018

End date 31 August 2020

Funded under

• EXCELLENT SCIENCE - Marie Skłodowska-Curie Actions

Total cost

€ 160 635,60

EU contribution

€ 160 635,60

Coordinated by

UNIVERSIDADE DO ALGARVE
Portugal

CORDIS provides links to public deliverables and publications of HORIZON projects.

Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Publications

Book chapters (2)

Monitoring the Transcriptional Activity of FOXO Transcription Factors by Analyzing their Target Genes

Author(s): Vanessa Henriques, Susana Machado, Wolfgang Link, Bibiana I. Ferreira
Published in: FOXO Transcription Factors - Methods and Protocols, Issue 1890, 2019, Page(s) 103-113, ISBN 978-1-4939-8899-0
Publisher: Springer New York
DOI: 10.1007/978-1-4939-8900-3_9

Image-based Identification of Chemical Compounds Capable of Trapping FOXO in the Cell Nucleus

Author(s): Susana Machado, Catarina Raposo, Bibiana I. Ferreira, Wolfgang Link
Published in: FOXO Transcription Factors - Methods and Protocols, Issue 1890, 2019, Page(s) 163-170, ISBN 978-1-4939-8899-0
Publisher: Springer New York
DOI: 10.1007/978-1-4939-8900-3_14

Peer reviewed articles (5)

The Emerging Therapeutic Landscape of Advanced Melanoma

Author(s): Vanessa Henriques, Teresa Martins, Wolfgang Link, Bibiana I. Ferreira
Published in: Current Pharmaceutical Design, Issue 24/5, 2018, Page(s) 549-558, ISSN 1381-6128
Publisher: Bentham Science Publishers
DOI: 10.2174/1381612824666180125093357

Tribbles Pseudokinases in Colorectal Cancer

Author(s): Bibiana I. Ferreira, Bruno Santos, Wolfgang Link, Ana Luísa De Sousa-Coelho
Published in: Cancers, Issue 13/11, 2021, Page(s) 2825, ISSN 2072-6694
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/cancers13112825

Small Molecule Inhibitors of CRM1

Author(s): Bibiana I. Ferreira, Bastien Cautain, Inês Grenho, Wolfgang Link
Published in: Frontiers in Pharmacology, Issue 11, 2020, ISSN 1663-9812
Publisher: Frontiers Media S.A.
DOI: 10.3389/fphar.2020.00625

CRISPR/Cas9‐mediated genome editing: From basic research to translational medicine

Author(s): Filipe V. Jacinto, Wolfgang Link, Bibiana I. Ferreira
Published in: Journal of Cellular and Molecular Medicine, Issue 24/7, 2020, Page(s) 3766-3778, ISSN 1582-1838
Publisher: Wiley-Blackwell
DOI: 10.1111/jcmm.14916

Harmine and Piperlongumine Revert TRIB2-Mediated Drug Resistance

Author(s): Susana Machado, Andreia Silva, Ana Luísa De Sousa-Coelho, Isabel Duarte, Inês Grenho, Bruno Santos, Victor Mayoral-Varo, Diego Megias, Fátima Sánchez-Cabo, Ana Dopazo, Bibiana I. Ferreira, Wolfgang Link
Published in: Cancers, Issue 12/12, 2020, Page(s) 3689, ISSN 2072-6694
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/cancers12123689

Thesis and dissertations (3)

CRISPR: applications in human pathologies and future prospects

Author(s): Author: Franco, Hannah Sabrina Advisor: Cancela, Leonor/ Ferreira, Bibiana
Published in: 2018
Publisher: Sapientia

Study of the TRIB2 protein network

Author(s): Author: Raposo, Catarina Martins Advisor: Link, Wolfgang / Ferreira, Bibiana
Published in: 2019
Publisher: Saptientia

Characterization of TRIB2-mediated resistance topharmacological inhibition of MEK

Author(s): Henriques VM, Link W, Ferreira BI.
Published in: 2017
Publisher: Sapientia - Universidade do Algarve