Objective
An ageing population as well as chronic and infectious diseases, pandemic threats and antimicrobial resistance are currently on the rise. As a consequence, increasing attention is paid to the development of novel drugs, treatments and personal care products. In this context, blue biotechnology offers an opportunity to explore the potential of the marine microbial world to produce biological active metabolites, which may support health and wellbeing. The general goal of this proposal is the extraction and identification of biologically active substances in one of the largest reservoirs of organic material on Earth: the recalcitrant marine dissolved organic matter (RDOM) pool. This pool is an unexplored potential source of bioactive substances. For this purpose, the RDOM will be extracted from (1) one of the oldest water masses of the global ocean located at intermediate depths of the North Pacific and (2) the reworked DOM of marine sediments porewater in the North Sea. A comparative screen will be performed with the more recent surface oceanic water of the North Pacific. The antioxidant, immunostimulant and antitumoral potential of these DOM samples will be explored to evaluate possible cosmetical and pharmaceutical suitability. The DOM molecular diversity and features identified by mass spectrometry and nuclear magnetic resonance will be correlated with the different modes of bioactivity. This proposal will enable Dr. Catalá to broaden her expertise on molecular characterization of the DOM pool, to learn new methodologies of bioactive substances identification as well as to meet future challenges on marine natural product research, endorsed by the H2020 Societal Challenges of 'Health, Demographic Change and Wellbeing' and 'Marine Research and the Bioeconomy'. This combination of expertise is unique, and thus will be a milestone in Dr. Catalá career towards an independent scientist of high international visibility.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
- medical and health sciences clinical medicine oncology prostate cancer
- natural sciences earth and related environmental sciences oceanography
- natural sciences chemical sciences analytical chemistry mass spectrometry
- natural sciences biological sciences microbiology
- natural sciences earth and related environmental sciences geochemistry biogeochemistry
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Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
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H2020-EU.1.3. - EXCELLENT SCIENCE - Marie Skłodowska-Curie Actions
MAIN PROGRAMME
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H2020-EU.1.3.2. - Nurturing excellence by means of cross-border and cross-sector mobility
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Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
MSCA-IF-EF-ST - Standard EF
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Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
(opens in new window) H2020-MSCA-IF-2016
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Net EU financial contribution. The sum of money that the participant receives, deducted by the EU contribution to its linked third party. It considers the distribution of the EU financial contribution between direct beneficiaries of the project and other types of participants, like third-party participants.
26129 Oldenburg
Germany
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.