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Biodegradable Water-Soluble Cylindrical Block Copolymer Micelles and their Applications in Nanomedicine

Objective

Block copolymer (BCP) self-assembly in solution has attracted considerable attention for many decades because it can yield ordered nanoscopic core-shell structures (micelles) with a wide range of morphologies. These aggregates offer potential applications in many fields, and cylinders are among the most promising for uses in nanomedicine (e.g. as drug delivery vehicles). In this proposal, state-of-the-art strategies to access well-defined micelles with tailored structures will be applied to the preparation of biodegradable monodisperse cylindrical micelles and block comicelles in water. Once formed, the micelles and their hierarchical assemblies will be characterized in detail and explored in potential nanomedical applications. To achieve these objectives Dr. Jia Tian, an exceptionally talented young scientist from China who performed his Ph.D. in a top supramolecular chemistry group in China (Zhan-Ting Li, Fudan University), will work in the internationally leading polymer and materials research group of Prof. Ian Manners (Bristol, UK) where he will learn polymer synthesis and state-of-the-art self-assembly techniques and will obtain a broad background in polymer and BCP synthesis, self-assembly, and polymer materials science. Armed with the new knowledge and experience gained, following the fellowship Dr. Tian aims to obtain an academic position in China where soft materials such as biodegradable BCPs and their applications in nanomedicine will play a key role.

Fields of science (EuroSciVoc)

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Keywords

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Programme(s)

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Topic(s)

Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.

Funding Scheme

Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.

MSCA-IF - Marie Skłodowska-Curie Individual Fellowships (IF)

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Call for proposal

Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.

(opens in new window) H2020-MSCA-IF-2016

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Coordinator

UNIVERSITY OF BRISTOL
Net EU contribution

Net EU financial contribution. The sum of money that the participant receives, deducted by the EU contribution to its linked third party. It considers the distribution of the EU financial contribution between direct beneficiaries of the project and other types of participants, like third-party participants.

€ 195 454,80
Address
BEACON HOUSE QUEENS ROAD
BS8 1QU BRISTOL
United Kingdom

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Region
South West (England) Gloucestershire, Wiltshire and Bristol/Bath area Bristol, City of
Activity type
Higher or Secondary Education Establishments
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Total cost

The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.

€ 195 454,80
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