Development of novel computational biology pipeline for the efficient classification of titin SNPs for clinical use

Project Information

TTNPred

Grant agreement ID: 753054

DOI 10.3030/753054

Project closed

EC signature date 17 October 2017

Start date 1 January 2018

End date 28 February 2020

Funded under

• EXCELLENT SCIENCE - Marie Skłodowska-Curie Actions

Total cost € 171 460,80

EU contribution € 171 460,80

Coordinated by

UNIVERSITAT KONSTANZ
Germany

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Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Publications

Peer reviewed articles (4)

Self-Assembling Proteins as High-Performance Substrates for Embryonic Stem Cell Self-Renewal

Author(s): Christopher J. Hill, Jennifer R. Fleming, Masoumeh Mousavinejad, Rachael Nicholson, Svetomir B. Tzokov, Per A. Bullough, Julius Bogomolovas, Mark R. Morgan, Olga Mayans, Patricia Murray
Published in: Advanced Materials, 2019, Page(s) 1807521, ISSN 0935-9648
Publisher: United Nations Industrial Developement Organization
DOI: 10.1002/adma.201807521

Scalable, Non-denaturing Purification of Phosphoproteins Using Ga3+-IMAC: N2A and M1M2 Titin Components as Study case

Author(s): Michael Adams, Jennifer R. Fleming, Eva Riehle, Tiankun Zhou, Thomas Zacharchenko, Marija Markovic, Olga Mayans
Published in: The Protein Journal, Issue 38/2, 2019, Page(s) 181-189, ISSN 1572-3887
Publisher: Springer Verlag
DOI: 10.1007/s10930-019-09815-w

The ZT Biopolymer: A Self-Assembling Protein Scaffold for Stem Cell Applications

Author(s): Yevheniia Nesterenko, Christopher J. Hill, Jennifer R. Fleming, Patricia Murray, Olga Mayans
Published in: International Journal of Molecular Sciences, Issue 20/17, 2019, Page(s) 4299, ISSN 1422-0067
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms20174299

The importance of chain context in assessing small nucleotide variants in titin: in silico case study of the I10-I11 tandem and its arrhythmic right ventricular cardiomyopathy linked position T2580

Author(s): J. R. Fleming, D. J. Rigden, O. Mayans
Published in: Journal of Biomolecular Structure and Dynamics, 2020, Page(s) 1-11, ISSN 0739-1102
Publisher: Adenine Press
DOI: 10.1080/07391102.2020.1768148