Objective
Presbyopia, the age-related loss of the ability of the eye to focus near and far objects, affects 1.2 billion people in the world. While there are a number of corrections for presbyopia available (near and progressive spectacles, monovision or multifocal lenses) none of these restore the dynamic focusing capability of the young crystalline lens.
Replacing of the rigid crystalline lens in the aged eye by a shape-changing artificial lens able to respond an accommodative demand, therefore restoring accommodation in the aging eye, will undoubtedly increase the quality of vision, quality of life and productivity of millions of presbyopes worldwide.
Presbyopia ERC Advanced Grant Presbyopia investigates basic mechanisms of the crystalline lens accommodation, to propose nature-inspired IOL designs to correct presbyopia. Imaging technologies developed during the project have allowed imaging-based quantification of the crystalline lens structure and its change with accommodation, aging and treatment. Knowledge gathered using these technologies, and developments combining optics, biomechanics, biomaterials and photo-chemistry have allowed a new concept for an accommodating IOL, of which the first prototypes have been manufactured and tested, therefore materializing the ultimate goal of the Presbyopia ERC AdG grant. This research has allowed to propose, develop and test a novel surface-change accommodating IOL, and a disruptive photo-activated method to transmit the forces from the eye muscle into the lens, both protected by patents filed during the ERC AdG.
The Light-AIOL ERC-Proof of Concept aims at evaluating the marketability of the developed AIOL platform and at reaching a product commercialization plan to be presented to industrial and financial investors with the ultimate goal of bringing to market this technology, and move to a phase closer to deployment in patients. This should bring surgical corrections of presbyopia into a new paradigm.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
- natural sciences chemical sciences physical chemistry photochemistry
- social sciences economics and business economics production economics productivity
- natural sciences physical sciences optics
- natural sciences biological sciences biophysics
- engineering and technology industrial biotechnology biomaterials
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Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
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H2020-EU.1.1. - EXCELLENT SCIENCE - European Research Council (ERC)
MAIN PROGRAMME
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Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
ERC-POC - Proof of Concept Grant
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Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
(opens in new window) ERC-2016-PoC
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Net EU financial contribution. The sum of money that the participant receives, deducted by the EU contribution to its linked third party. It considers the distribution of the EU financial contribution between direct beneficiaries of the project and other types of participants, like third-party participants.
28006 MADRID
Spain
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.