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Decomposing Heterogeneity in Autism Spectrum Disorders

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Publications

Imbalanced social-communicative and restricted repetitive behavior subtypes of autism spectrum disorder exhibit different neural circuitry

Author(s): Natasha Bertelsen, Isotta Landi, Richard A. I. Bethlehem, Jakob Seidlitz, Elena Maria Busuoli, Veronica Mandelli, Eleonora Satta, Stavros Trakoshis, Bonnie Auyeung, Prantik Kundu, Eva Loth, Guillaume Dumas, Sarah Baumeister, Christian F. Beckmann, Sven Bölte, Thomas Bourgeron, Tony Charman, Sarah Durston, Christine Ecker, Rosemary J. Holt, Mark H. Johnson, Emily J. H. Jones, Luke Mason, Andreas M
Published in: Communications Biology, 4/1, 2021, ISSN 2399-3642
Publisher: Springer Nature
DOI: 10.1038/s42003-021-02015-2

reval: A Python package to determine best clustering solutions with stability-based relative clustering validation

Author(s): Isotta Landi, Veronica Mandelli, Michael V. Lombardo
Published in: Patterns, 2/4, 2021, Page(s) 100228, ISSN 2666-3899
Publisher: Cell Press
DOI: 10.1016/j.patter.2021.100228

Sex-specific impact of prenatal androgens on social brain default mode subsystems

Author(s): Michael V. Lombardo, Bonnie Auyeung, Tiziano Pramparo, Angélique Quartier, Jérémie Courraud, Rosemary J. Holt, Jack Waldman, Amber N. V. Ruigrok, Natasha Mooney, Richard A. I. Bethlehem, Meng-Chuan Lai, Prantik Kundu, Edward T. Bullmore, Jean-Louis Mandel, Amélie Piton, Simon Baron-Cohen
Published in: Molecular Psychiatry, 2019, ISSN 1359-4184
Publisher: Nature Publishing Group
DOI: 10.1038/s41380-018-0198-y

Big data approaches to decomposing heterogeneity across the autism spectrum

Author(s): Michael V. Lombardo, Meng-Chuan Lai, Simon Baron-Cohen
Published in: Molecular Psychiatry, 24, 2019, Page(s) 1435–1450, ISSN 1359-4184
Publisher: Nature Publishing Group
DOI: 10.1038/s41380-018-0321-0

Large-scale associations between the leukocyte transcriptome and BOLD responses to speech differ in autism early language outcome subtypes

Author(s): Michael V. Lombardo, Tiziano Pramparo, Vahid Gazestani, Varun Warrier, Richard A. I. Bethlehem, Cynthia Carter Barnes, Linda Lopez, Nathan E. Lewis, Lisa Eyler, Karen Pierce, Eric Courchesne
Published in: Nature Neuroscience, 21/12, 2018, Page(s) 1680-1688, ISSN 1097-6256
Publisher: Nature Publishing Group
DOI: 10.1038/s41593-018-0281-3

Neural self-representation in autistic women and association with ‘compensatory camouflaging’

Author(s): Meng-Chuan Lai, Michael V Lombardo, Bhismadev Chakrabarti, Amber NV Ruigrok, Edward T Bullmore, John Suckling, Bonnie Auyeung, Francesca Happé, Peter Szatmari, Simon Baron-Cohen, Anthony J Bailey, Patrick F Bolton, Sarah Carrington, Marco Catani, Michael C Craig, Eileen M Daly, Sean CL Deoni, Christine Ecker, Julian Henty, Peter Jezzard, Patrick Johnston, Derek K Jones, Anya Madden, Diane Mullins
Published in: Autism, 23, 2018, Page(s) 136236131880715, ISSN 1362-3613
Publisher: SAGE Publications
DOI: 10.1177/1362361318807159

The ASD Living Biology: from cell proliferation to clinical phenotype

Author(s): Eric Courchesne, Tiziano Pramparo, Vahid H. Gazestani, Michael V. Lombardo, Karen Pierce, Nathan E. Lewis
Published in: Molecular Psychiatry, 24/1, 2019, Page(s) 88-107, ISSN 1359-4184
Publisher: Nature Publishing Group
DOI: 10.1038/s41380-018-0056-y

Large-scale analyses of the relationship between sex, age and intelligence quotient heterogeneity and cortical morphometry in autism spectrum disorder

Author(s): Saashi A. Bedford, Min Tae M. Park, Gabriel A. Devenyi, Stephanie Tullo, Jurgen Germann, Raihaan Patel, Evdokia Anagnostou, Simon Baron-Cohen, Edward T. Bullmore, Lindsay R. Chura, Michael C. Craig, Christine Ecker, Dorothea L. Floris, Rosemary J. Holt, Rhoshel Lenroot, Jason P. Lerch, Michael V. Lombardo, Declan G. M. Murphy, Armin Raznahan, Amber N. V. Ruigrok, Elizabeth Smith, Michael D. Spence
Published in: Molecular Psychiatry, 2019, ISSN 1359-4184
Publisher: Nature Publishing Group
DOI: 10.1038/s41380-019-0420-6

Default mode-visual network hypoconnectivity in an autism subtype with pronounced social visual engagement difficulties

Author(s): Michael V Lombardo, Lisa Eyler, Adrienne Moore, Michael Datko, Cynthia Carter Barnes, Debra Cha, Eric Courchesne, Karen Pierce
Published in: eLife, 8, 2019, Page(s) e47427, ISSN 2050-084X
Publisher: eLife Sciences Publications
DOI: 10.7554/elife.47427

Intrinsic excitation-inhibition imbalance affects medial prefrontal cortex differently in autistic men versus women

Author(s): Stavros Trakoshis, Pablo Martínez-Cañada, Federico Rocchi, Carola Canella, Wonsang You, Bhismadev Chakrabarti, Amber NV Ruigrok, Edward T Bullmore, John Suckling, Marija Markicevic, Valerio Zerbi, Simon Baron-Cohen, Alessandro Gozzi, Meng-Chuan Lai, Stefano Panzeri, Michael V Lombardo
Published in: eLife, 9, 2020, ISSN 2050-084X
Publisher: eLife Sciences Publications
DOI: 10.7554/elife.55684