Gene editing and in vitro approaches to understand conceptus elongation in ungulates

Project Information

ELONGAN

Grant agreement ID: 757886

DOI

10.3030/757886

Project closed

EC signature date 15 September 2017

Start date 1 October 2017

End date 30 September 2023

Funded under

• EXCELLENT SCIENCE - European Research Council (ERC)

Total cost

€ 1 480 880,00

EU contribution

€ 1 480 880,00

Coordinated by

AGENCIA ESTATAL CONSEJO SUPERIOR DE INVESTIGACIONES CIENTIFICAS
Spain

CORDIS provides links to public deliverables and publications of HORIZON projects.

Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Deliverables

Open Research Data Pilot (1)

Data Management Plan

Data Management Plan for Open Research Data Pilot

Publications

Peer reviewed articles (14)

Embryonic disc formation following post-hatching bovine embryo development in vitro

Author(s): Priscila Ramos-Ibeas, Ismael Lamas-Toranzo, Álvaro Martínez-Moro, Celia de Frutos, Alejandra C Quiroga, Esther Zurita, Pablo Bermejo-Álvarez
Published in: Reproduction, Issue 160/4, 2020, Page(s) 579-589, ISSN 1470-1626
Publisher: Society for Reproduction and Fertility
DOI: 10.1530/rep-20-0243

Transforming growth factor beta (TGFβ) pathway is essential for hypoblast and epiblast development in ovine post-hatching embryos

Author(s): Beatriz Galiano-Cogolludo, Pilar Marigorta, Víctor Yus Girón, Pablo Bermejo-Álvarez, Priscila Ramos-Ibeas
Published in: Theriogenology, Issue 196, 2022, Page(s) 112-120, ISSN 0093-691X
Publisher: Elsevier BV
DOI: 10.1016/j.theriogenology.2022.11.021

Effect of arachidonic acid on pre- and post-hatching in vitro bovine embryo development

Author(s): Leopoldo González-Brusi, Alba Pérez-Gómez, Alejandra C Quiroga, Carolina Tamargo, Pablo Bermejo-Álvarez
Published in: Reproduction, Fertility and Development, Issue 35(12), 2023, Page(s) 614-621, ISSN 1031-3613
Publisher: Commonwealth Scientific and Industrial Research Organization Publishing
DOI: 10.1071/rd23053

In vitro culture of ovine embryos up to early gastrulating stages

Author(s): Priscila Ramos-Ibeas, Leopoldo González-Brusi, María Torres Used, María Jesús Cocero, Pilar Marigorta, Ramiro Alberio, Pablo Bermejo-Álvarez
Published in: Development, Issue 149(6), 2022, Page(s) dev199743, ISSN 0950-1991
Publisher: The Company of Biologists Ltd.
DOI: 10.1242/dev.199743

Pre-hatching exposure to N2B27 medium improves post-hatching development of bovine embryos in vitro

Author(s): Priscila Ramos-Ibeas, Alba Pérez-Gómez, Leopoldo González-Brusi, Alejandra C Quiroga, Pablo Bermejo-Álvarez
Published in: Theriogenology, Issue 205, 2023, Page(s) 73-78, ISSN 0093-691X
Publisher: Elsevier BV
DOI: 10.1016/j.theriogenology.2023.04.018

Intergenerational transmission of the positive effects of physical exercise on brain and cognition

Author(s): Kerry R. McGreevy, Patricia Tezanos, Iria Ferreiro-Villar, Anna Pallé, Marta Moreno-Serrano, Anna Esteve-Codina, Ismael Lamas-Toranzo, Pablo Bermejo-Álvarez, Julia Fernández-Punzano, Alejandro Martín-Montalvo, Raquel Montalbán, Sacri R. Ferrón, Elizabeth J. Radford, Ángela Fontán-Lozano, José Luis Trejo
Published in: Proceedings of the National Academy of Sciences, Issue 116/20, 2019, Page(s) 10103-10112, ISSN 0027-8424
Publisher: National Academy of Sciences
DOI: 10.1073/pnas.1816781116

Lineage Differentiation Markers as a Proxy for Embryo Viability in Farm Ungulates.

Author(s): Alba Pérez-Gómez; Leopoldo González-Brusi; Pablo Bermejo-Alvarez; Priscila Ramos-Ibeas
Published in: Frontiers in Veterinary Science, Vol 8 (2021), Issue Vol 8, 2021, ISSN 2297-1769
Publisher: Frontiers
DOI: 10.3389/fvets.2021.680539

Mitochondrial and metabolic adjustments during the final phase of follicular development prior to IVM of bovine oocytes

Author(s): Ismael Lamas-Toranzo, Eva Pericuesta, Pablo Bermejo-Álvarez
Published in: Theriogenology, Issue 119, 2018, Page(s) 156-162, ISSN 0093-691X
Publisher: Elsevier BV
DOI: 10.1016/j.theriogenology.2018.07.007

Directions and applications of CRISPR technology in livestock research

Author(s): Ismael Lamas-Toranzo, Priscila Ramos-Ibeas, Eva Pericuesta, Pablo Bermejo-Álvarez
Published in: Animal Reproduction, Issue 15/3, 2018, Page(s) 292-300, ISSN 1984-3143
Publisher: Brazilian College of Animal Reproduction
DOI: 10.21451/1984-3143-ar2018-0075

ZP4 confers structural properties to the zona pellucida essential for embryo development

Author(s): Ismael Lamas-Toranzo, Noelia Fonseca Balvís, Ana Querejeta-Fernández, María José Izquierdo-Rico, Leopoldo González-Brusi, Pedro L Lorenzo, Pilar García-Rebollar, Manuel Avilés, Pablo Bermejo-Álvarez
Published in: eLife, Issue 8, 2019, ISSN 2050-084X
Publisher: eLife Sciences Publications
DOI: 10.7554/elife.48904

Strategies to reduce genetic mosaicism following CRISPR-mediated genome edition in bovine embryos

Author(s): I. Lamas-Toranzo, B. Galiano-Cogolludo, F. Cornudella-Ardiaca, J. Cobos-Figueroa, O. Ousinde, P. Bermejo-Álvarez
Published in: Scientific Reports, Issue 9/1, 2019, ISSN 2045-2322
Publisher: Nature Publishing Group
DOI: 10.1038/s41598-019-51366-8

RS-1 enhances CRISPR-mediated targeted knock-in in bovine embryos

Author(s): I. Lamas-Toranzo, A. Martínez-Moro, E. O´Callaghan, G. Millán-Blanca, J.M. Sánchez, P. Lonergan, P. Bermejo-Álvarez
Published in: Molecular Reproduction and Development, 2020, ISSN 1040-452X
Publisher: John Wiley & Sons Inc.
DOI: 10.1002/mrd.23341

TMEM95 is a sperm membrane protein essential for mammalian fertilization

Author(s): Ismael Lamas-Toranzo, Julieta G Hamze, Enrica Bianchi, Beatriz Fernández-Fuertes, Serafín Pérez-Cerezales, Ricardo Laguna-Barraza, Raúl Fernández-González, Pat Lonergan, Alfonso Gutiérrez-Adán, Gavin J Wright, María Jiménez-Movilla, Pablo Bermejo-Álvarez
Published in: eLife, Issue 9, 2020, ISSN 2050-084X
Publisher: eLife Sciences Publications
DOI: 10.7554/elife.53913

JUNO protein coated beads: A potential tool to predict bovine sperm fertilizing ability

Author(s): Julieta Gabriela Hamze, José María Sánchez, Elena O’Callaghan, Michael McDonald, Pablo Bermejo-Álvarez, Raquel Romar, Patrick Lonergan, María Jiménez-Movilla
Published in: Theriogenology, Issue 155, 2020, Page(s) 168-175, ISSN 0093-691X
Publisher: Elsevier BV
DOI: 10.1016/j.theriogenology.2020.05.025

Thesis and dissertations (1)

Desarrollo y aplicación de la tecnología CRISPR para el estudio de procesos reproductivos en mamíferos

Author(s): Lamas Toranzo, Ismael
Published in: reponame:E-Prints Complutense. Archivo Institucional de la UCM, Issue 1, 2021
Publisher: Universidad Complutense de Madrid