Computational modelling for personalised treatment of congenital craniofacial abnormalities

Project Information

CAD4FACE

Grant agreement ID: 757923

DOI

10.3030/757923

Project closed

EC signature date 26 February 2018

Start date 1 March 2018

End date 28 February 2025

Funded under

• EXCELLENT SCIENCE - European Research Council (ERC)

Total cost

€ 1 498 772,00

EU contribution

€ 1 498 772,00

Coordinated by

UNIVERSITY COLLEGE LONDON
United Kingdom

CORDIS provides links to public deliverables and publications of HORIZON projects.

Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Publications

Peer reviewed articles (34)

Correlation between head shape and volumetric changes following spring-assisted posterior vault expansion

Author(s): Karan R R Ramdat Misier, Richard W F Breakey, Lara S van de Lande, Benedetta Biffi, Paul G M Knoops, Silvia Schievano, Cornelia J J M Caron, David J Dunaway, Maarten J Koudstaal, N U Owase Jeelani, Alessandro Borghi
Published in: Journal of Cranio-Maxillofacial Surgery, Issue 10105182, 2022, ISSN 1010-5182
Publisher: Churchill Livingstone
DOI: 10.1016/j.jcms.2021.05.004

In Vitro Assessment of the Neuro-Compatibility of Fe-20Mn as a Potential Bioresorbable Material for Craniofacial Surgery

Author(s): 158. Ajami S, Kraaneveld C, Koudstaal M, Dunaway D, Jeelani NUO, Schievano S, Bregoli C, Fiocchi J, Biffi CA, Tuissi A, Alessandro Borghi
Published in: Medicina (Kaunas), 2024, ISSN 1648-9144
Publisher: MDPI
DOI: 10.3390/medicina60030440

Computational Evaluation of Potential Correction Methods for Unicoronal Craniosynostosis

Author(s): Selim Bozkurt, Alessandro Borghi, Owase Jeelani, David Dunaway, Silvia Schievano
Published in: Journal of Craniofacial Surgery, Issue 31/3, 2020, Page(s) 692-696, ISSN 1049-2275
Publisher: Lippincott Williams & Wilkins Ltd.
DOI: 10.1097/scs.0000000000006186

Towards a radiation free numerical modelling framework to predict spring assisted correction of scaphocephaly

Author(s): Garate Andikoetxea B, Ajami S, Rodriguez-Florez N, Jeelani NUO, Dunaway D, Schievano S, Alessandro Borghi
Published in: Comput Methods Biomech Biomed Engin, 2023, ISSN 2168-1163
Publisher: Taylor and Francis Online
DOI: 10.1080/10255842.2023.2294262

The Esthetic Perception of Morphological Severity in Scaphocephalic Patients is Correlated With Specific Head Geometrical Features

Author(s): Alessandro Borghi, P Heutinck, N Rodriguez-Florez, M Koudstaal, F Ruggiero, S Ajami, S Schievano, N U O Jeelani, D Dunaway
Published in: The Cleft Palate-Craniofacial Journal, Issue 10556656, 2022, ISSN 1055-6656
Publisher: Allerton Press Inc.
DOI: 10.1177/10556656221111307

Two-Center Review of Posterior Vault Expansion following a Staged or Expectant Treatment of Crouzon and Apert Craniosynostosis

Author(s): Breakey RWF, Mercan E, Lara S van de Lande, Sidpra J, Birgfeld C, Lee A, Schievano S, Dunaway DJ, Jeelani NO, Hopper RA.
Published in: Plast Reconstr Surg., 2023, ISSN 2169-7574
Publisher: Lippincott
DOI: 10.1097/prs.0000000000009925

Local Soft Tissue and Bone Displacements Following Midfacial Bipartition Distraction in Apert Syndrome – Quantification Using a Semi-Automated Method

Author(s): Lara S. van de Lande, Eimear O'Sullivan, Paul G.M. Knoops, Athanasios Papaioannou, Juling Ong, Greg James, N. Owase Jeelani, Silvia Schievano, David J. Dunaway
Published in: Journal of Craniofacial Surgery, Issue 32, 2023, Page(s) 2646-2650, ISSN 1049-2275
Publisher: Lippincott Williams & Wilkins Ltd.
DOI: 10.1097/scs.0000000000007875

Validation of an in-silico modelling platform for outcome prediction in spring assisted posterior vault expansion

Author(s): Lara Deliège, Karan Ramdat Misier, Selim Bozkurt, William Breakey, Greg James, Juling Ong, David Dunaway, N U Owase Jeelani, Silvia Schievano, Alessandro Borghi
Published in: Clinical Biomechanics, 2021, ISSN 0268-0033
Publisher: Pergamon Press Ltd.
DOI: 10.1016/j.clinbiomech.2021.105424

Spring-assisted posterior vault expansion-a single-centre experience of 200 cases.

Author(s): R. William F. Breakey; Lara S van de Lande; Jai Sidpra; Paul M. Knoops; Alessandro Borghi; Justine O'Hara; Juling Ong; Greg James; Richard Hayward; Silvia Schievano; David Dunaway; N ul Owase Jeelani; N ul Owase Jeelani
Published in: Child's Nervous System, Issue 02567040, 2021, ISSN 0256-7040
Publisher: Springer Verlag
DOI: 10.1007/s00381-021-05330-5

Developing and testing an algorithm for automatic segmentation of the fetal face from three-dimensional ultrasound images

Author(s): A. E. Clark, B. Biffi, R. Sivera, A. Dall'Asta, L. Fessey, T.-L. Wong, G. Paramasivam, D. Dunaway, S. Schievano, C. C. Lees
Published in: Royal Society Open Science, Issue 7, 2021, Page(s) 201342, ISSN 2054-5703
Publisher: The Royal Society
DOI: 10.1098/rsos.201342

Correlation of Intracranial Volume With Head Surface Volume in Patients With Multisutural Craniosynostosis

Author(s): Karan R.R. Ramdat Misier, Richard W.F. Breakey, Cornelia J.J.M. Caron, Silvia Schievano, David J. Dunaway, Maarten J. Koudstaal, Owase N.U. Jeelani, Alessandro Borghi
Published in: Journal of Craniofacial Surgery, Issue Publish Ahead of Print, 2020, ISSN 1049-2275
Publisher: Lippincott Williams & Wilkins Ltd.
DOI: 10.1097/scs.0000000000006372

Spring-assisted posterior vault expansion: a parametric study to improve the intracranial volume increase prediction

Author(s): Lara Deliège, Ramdat Misier K, Silva D, James G, Ong J, Dunaway D, Jeelani NUO, Schievano S, Alessandro Borghi
Published in: Sci Rep, 2023, ISSN 2045-2322
Publisher: Nature Publishing Group
DOI: 10.1038/s41598-023-48143-z

3D Calvarial Growth in Spring-assisted Cranioplasty for Correction of Sagittal Synostosis

Author(s): Naiara Rodriguez-Florez, Alessandro Borghi, Daniel D. Yauwan, Pam Heuntinck, Jan L. Bruse, Maik Tenhagen, Özge K. Göktekin, Freida Angullia, Silvia Schievano, David J. Dunaway, Noor Ul Owase Jeelani, Greg James
Published in: Journal of Craniofacial Surgery, Issue Publish Ahead of Print, 2020, ISSN 1049-2275
Publisher: Lippincott Williams & Wilkins Ltd.
DOI: 10.1097/scs.0000000000006863

Fetal face shape analysis from prenatal 3D ultrasound images

Author(s): Sivera, Raphael; Clark, Anna E; Dall’Asta, Andrea; Ghi, Tullio; Schievano, Silvia; Lees, Christoph C
Published in: Scientific Reports , 14 , Article 4411, Issue 6, 2024, ISSN 2045-2322
Publisher: Nature Publishing Group
DOI: 10.21203/rs.3.rs-3112689/v1

The Accuracy of Computer-Assisted Surgical Planning in Predicting Soft Tissue Responses After Le Fort I Osteotomy: Retrospective Analysis

Author(s): Şenyürek SA, Ajami S, Ruggiero F, Van de Lande L, Caron CJJM, Schievano S, Dunaway DJ, Padwa B, Koudstaal MJ, Alessandro Borghi
Published in: J Craniofac Surg, 2022, ISSN 1049-2275
Publisher: Lippincott Williams & Wilkins Ltd.
DOI: 10.1097/scs.0000000000008970

Maxillary Changes Following Facial Bipartition – A Three-Dimensional Quantification

Author(s): Alexander J. Rickart, Lara S. van de Lande, Eimear O'Sullivan, Juling Ong, Daljit S. Gill, Robert D. Evans, Silvia Schievano, David J. Dunaway
Published in: Journal of Craniofacial Surgery, Issue 32, 2023, Page(s) 2053-2057, ISSN 1049-2275
Publisher: Lippincott Williams & Wilkins Ltd.
DOI: 10.1097/scs.0000000000007632

Parametrizing the genioplasty: a biomechanical virtual study on soft tissue behavior

Author(s): F Ruggiero, G Badiali, M Bevini, C Marchetti, J Ong, F Bolognesi, S Schievano, D Dunaway, A Bianchi, A Borghi
Published in: Int J Comput Assist Radiol Surg., Issue 18616410, 2022, ISSN 1861-6410
Publisher: Springer Verlag
DOI: 10.1007/s11548-021-02489-9

Statistical shape modelling for the analysis of head shape variations

Author(s): Pam Heutinck, Paul Knoops, Naiara Rodriguez Florez, Benedetta Biffi, William Breakey, Greg James, Maarten Koudstaal, Silvia Schievano, David Dunaway, Owase Jeelani, Alessandro Borghi
Published in: Journal of Cranio-Maxillofacial Surgery, Issue 10105182, 2021, ISSN 1010-5182
Publisher: Churchill Livingstone
DOI: 10.1016/j.jcms.2021.02.020

Mechanical and morphological properties of parietal bone in patients with sagittal craniosynostosis

Author(s): Sara Ajami, Naiara Rodriguez-Florez, Juling Ong, Noor Ul Owase Jeelani, David Dunaway, Greg James, Freida Angullia, Curtis Budden, Selim Bozkurt, Amel Ibrahim, Patrizia Ferretti, Silvia Schievano, Alessandro Borghi
Published in: Journal of the Mechanical Behavior of Biomedical Materials, Issue 17516161, 2022, ISSN 1751-6161
Publisher: Elsevier BV
DOI: 10.1016/j.jmbbm.2021.104929

Mapping the use of computational modelling and simulation in clinics: A survey

Author(s): Raphaëlle Lesage, Michiel Van Oudheusden, Silvia Schievano, Ine Van Hoyweghen, Liesbet Geris, Claudio Capelli
Published in: Frontiers in Medical Technology, Issue 5, 2023, ISSN 2673-3129
Publisher: Frontiers Media SA
DOI: 10.3389/fmedt.2023.1125524

A computational modelling tool for prediction of head reshaping following endoscopic strip craniectomy and helmet therapy for the treatment of scaphocephaly

Author(s): Lara Deliege, Alessandra Carriero, Juling Ong, Greg James, Owase Jeelani, David Dunaway, Petronella Stoltz, David Hersh, Jonathan Martin, Kathleen Carroll, Megan Chamis, Silvia Schievano, Markus Bookland, Alessandro Borghi
Published in: Computers in Biology and Medicine, Issue 177, 2024, Page(s) 108633, ISSN 0010-4825
Publisher: Pergamon Press Ltd.
DOI: 10.1016/j.compbiomed.2024.108633

Computational modelling of patient specific spring assisted lambdoid craniosynostosis correction

Author(s): Selim Bozkurt, Alessandro Borghi, Lara S. van de Lande, N. U. Owase Jeelani, David J. Dunaway, Silvia Schievano
Published in: Scientific Reports, Issue 10/1, 2020, ISSN 2045-2322
Publisher: Nature Publishing Group
DOI: 10.1038/s41598-020-75747-6

Does the Mutation Type Affect the Response to Cranial Vault Expansion in Children With Apert Syndrome?

Author(s): Mohammad R. Goodarzi, William F. Breakey, Lara S. van de Lande, Alessandro Borghi, Justine O’Hara, Juling Ong, Greg James, Richard Hayward, Silvia Schievano, David J. Dunaway, Nu Owase Jeelani
Published in: Journal of Craniofacial Surgery, Issue 34, 2024, Page(s) 910-913, ISSN 1049-2275
Publisher: Lippincott Williams & Wilkins Ltd.
DOI: 10.1097/scs.0000000000009126

“The Science Behind the Springs”—Using Biomechanics and Finite Element Modeling to Predict Outcomes in Spring-assisted Sagittal Synostosis Surgery

Author(s): Noor ul Owase Jeelani, Alessandro Borghi, Naiara Rodriguez Florez, Selim Bozkurt, David Dunaway, Silvia Schievano
Published in: Journal of Craniofacial Surgery, Issue Publish Ahead of Print, 2020, ISSN 1049-2275
Publisher: Lippincott Williams & Wilkins Ltd.
DOI: 10.1097/scs.0000000000006865

Cone beam CT for the assessment of bone microstructure to predict head shape changes after spring-assisted craniosynostosis surgery

Author(s): Tanya Wolffenbuttel, Sara Ajami, Alessandro Borghi, Silvia Schievano, David Dunaway, Noor ul Owase Jeelani, Maarten Koudstaal
Published in: Journal of Cranio-Maxillofacial Surgery, Issue 53, 2025, Page(s) 142-153, ISSN 1010-5182
Publisher: Churchill Livingstone
DOI: 10.1016/j.jcms.2024.11.014

Comparison of Internal and External Distraction in Frontofacial Monobloc Advancement: A Three-Dimensional Quantification

Author(s): Alexander J Rickart, Lara S van de Lande, Eimear O’ Sullivan, Kevin Bloch, Eric Arnaud, Silvia Schievano, Noor ul Owase Jeelani, Giovanna Paternoster, Roman Khonsari, David J Dunaway
Published in: Plastic & Reconstructive Surgery, 2024, ISSN 0032-1052
Publisher: Williams & Wilkins Co.
DOI: 10.1097/prs.0000000000010331

Finite element method for the design of implants for temporal hollowing

Author(s): Federica Ruggiero, David Dunaway, Curtis Budden, Luke Smith, Noor Ul Owase Jeelani, Silvia Schievano, Juling Ong, Alessandro Borghi
Published in: Journal of Plastic, Reconstructive & Aesthetic Surgery Open, Issue 17486815, 2021, ISSN 1748-6815
Publisher: Elsevier BV
DOI: 10.1016/j.jpra.2021.12.001

The 3D skull 0–4 years: A validated, generative, statistical shape model

Author(s): Eimear O' Sullivan, Lara S. van de Lande, Anne-Jet C. Oosting, Athanasios Papaioannou, N. Owase Jeelani, Maarten J. Koudstaal, Roman H. Khonsari, David J. Dunaway, Stefanos Zafeiriou, Silvia Schievano
Published in: Bone Reports, Issue 15, 2024, Page(s) 101154, ISSN 2352-1872
Publisher: Elsevier Inc.
DOI: 10.1016/j.bonr.2021.101154

A machine learning framework for automated diagnosis and computer-assisted planning in plastic and reconstructive surgery

Author(s): Paul G. M. Knoops, Athanasios Papaioannou, Alessandro Borghi, Richard W. F. Breakey, Alexander T. Wilson, Owase Jeelani, Stefanos Zafeiriou, Derek Steinbacher, Bonnie L. Padwa, David J. Dunaway, Silvia Schievano
Published in: Scientific Reports, Issue 9/1, 2019, ISSN 2045-2322
Publisher: Nature Publishing Group
DOI: 10.1038/s41598-019-49506-1

A population-specific material model for sagittal craniosynostosis to predict surgical shape outcomes

Author(s): Alessandro Borghi, Naiara Rodriguez Florez, Federica Ruggiero, Greg James, Justine O’Hara, Juling Ong, Owase Jeelani, David Dunaway, Silvia Schievano
Published in: Biomechanics and Modeling in Mechanobiology, 2019, ISSN 1617-7959
Publisher: Springer Verlag
DOI: 10.1007/s10237-019-01229-y

Growth patterns and shape development of the paediatric mandible – A 3D statistical model

Author(s): Eimear O' Sullivan, Lara S. van de Lande, Khalid El Ghoul, Maarten J. Koudstaal, Silvia Schievano, Roman H. Khonsari, David J. Dunaway, Stefanos Zafeiriou
Published in: Bone Reports, Issue 16, 2024, Page(s) 101528, ISSN 2352-1872
Publisher: Elsevier Inc.
DOI: 10.1016/j.bonr.2022.101528

Craniofacial Syndrome Identification Using Convolutional Mesh Autoencoders

Author(s): Eimear O'Sullivan, Lara Sophie van de Lande, Athanasios Papaioannou, Richard W.F. Breakey, N. Owase Jeelani, Allan Ponniah, Christian Duncan, Silvia Schievano, Roman Hossein Khonsari, Stefanos Zafeiriou, David James Dunaway
Published in: SSRN Electronic Journal, 2021, ISSN 1556-5068
Publisher: Elsevier BV
DOI: 10.2139/ssrn.3795325

Understanding the influence of surgical parameters on craniofacial surgery outcomes: a computational study

Author(s): K. H. He, J. L. Bruse, N. Rodriguez-Florez, D. Dunaway, O. Jeelani, S. Schievano, Alessandro Borghi
Published in: R Soc Open Sci, 2023, ISSN 2054-5703
Publisher: The Royal Society
DOI: 10.1098/rsos.231158

Convolutional mesh autoencoders for the 3-dimensional identification of FGFR-related craniosynostosis

Author(s): Eimear O’ Sullivan, Lara S. van de Lande, Athanasios Papaioannou, Richard W. F. Breakey, N. Owase Jeelani, Allan Ponniah, Christian Duncan, Silvia Schievano, Roman H. Khonsari, Stefanos Zafeiriou, David. J. Dunaway
Published in: Scientific Reports, Issue 12, 2022, ISSN 2045-2322
Publisher: Nature Publishing Group
DOI: 10.1038/s41598-021-02411-y