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Imaging Perfusion Restrictions from Extracellular Solid Stress

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Vascular dysfunction promotes regional hypoxia after bevacizumab therapy in recurrent glioblastoma patients

Author(s): Elizabeth R Gerstner, Kyrre E Emblem, Yi-Fen Yen, Jorg Dietrich, Justin T Jordan, Ciprian Catana, Kevin Lou Wenchin, Jacob M Hooker, Dan G Duda, Bruce R Rosen, Jayashree Kalpathy-Cramer, Rakesh K Jain, Tracy T Batchelor
Published in: Neuro-Oncology Advances, 2/1, 2020, Page(s) vdaa157, ISSN 2632-2498
Publisher: Oxford University Press
DOI: 10.1093/noajnl/vdaa157

The Impact of MRI Features and Observer Confidence on the Treatment Decision-Making for Patients with Untreated Glioma

Author(s): Paulina Due-Tønnessen, Marco C. Pinho, Kyrre E. Emblem, John K. Hald, Masafumi Kanoto, Andreas Abildgaard, Donatas Sederevicius, Inge R. Groote, Otto Rapalino, Atle Bjørnerud
Published in: Scientific Reports, 9/1, 2019, ISSN 2045-2322
Publisher: Nature Publishing Group
DOI: 10.1038/s41598-019-56333-x

MGMT methylation may benefit overall survival in patients with moderately vascularized glioblastomas

Author(s): Elies Fuster-Garcia, David Lorente Estellés, María del Mar Álvarez-Torres, Javier Juan-Albarracín, Eduard Chelebian, Alex Rovira, Cristina Auger Acosta, Jose Pineda, Laura Oleaga, Enrique Mollá-Olmos, Silvano Filice, Paulina Due-Tønnessen, Torstein R. Meling, Kyrre E. Emblem, Juan M. García-Gómez
Published in: European Radiology, 31/3, 2021, Page(s) 1738-1747, ISSN 0938-7994
Publisher: Springer Verlag
DOI: 10.1007/s00330-020-07297-4

Bevacizumab Reduces Permeability and Concurrent Temozolomide Delivery in a Subset of Patients with Recurrent Glioblastoma

Author(s): Elizabeth R. Gerstner, Kyrre E. Emblem, Ken Chang, Bella Vakulenko-Lagun, Yi-Fen Yen, Andrew L. Beers, Jorg Dietrich, Scott R. Plotkin, Ciprian Catana, Jacob M. Hooker, Dan G. Duda, Bruce Rosen, Jayashree Kalpathy-Cramer, Rakesh K. Jain, Tracy Batchelor
Published in: Clinical Cancer Research, 26/1, 2020, Page(s) 206-212, ISSN 1078-0432
Publisher: American Association for Cancer Research
DOI: 10.1158/1078-0432.ccr-19-1739

Noise dependency in vascular parameters from combined gradient-echo and spin-echo DSC MRI

Author(s): Ingrid Digernes, Line B Nilsen, Endre Grøvik, Atle Bjørnerud, Grethe Løvland, Einar Vik-Mo, Torstein R Meling, Cathrine Saxhaug, Åslaug Helland, Kari D Jacobsen, Oliver Geier, Kyrre E Emblem
Published in: Physics in Medicine & Biology, 65/22, 2020, Page(s) 225020, ISSN 1361-6560
Publisher: IOP Publishing on behalf of the Institute of Physics and Engineering in Medicine (IPEM).
DOI: 10.1088/1361-6560/abb71a

The impact of EPI-based distortion correction of dynamic susceptibility contrast MRI on cerebral blood volume estimation in patients with glioblastoma

Author(s): Ivar T. Hovden, Oliver M. Geier, Ingrid Digernes, Elies Fuster-Garcia, Grethe Løvland, Einar Vik-Mo, Torstein R. Meling, Kyrre E. Emblem
Published in: European Journal of Radiology, 132, 2020, Page(s) 109278, ISSN 0720-048X
Publisher: Elsevier BV
DOI: 10.1016/j.ejrad.2020.109278

Responses in the diffusivity and vascular function of the irradiated normal brain are seen up until 18 months following SRS of brain metastases

Author(s): Line Brennhaug Nilsen, Ingrid Digernes, Endre Grøvik, Cathrine Saxhaug, Anna Latysheva, Oliver Geier, Birger Breivik, Dag Ottar Sætre, Kari Dolven Jacobsen, Åslaug Helland, Kyrre Eeg Emblem
Published in: Neuro-Oncology Advances, 2/1, 2020, Page(s) vdaa028, ISSN 2632-2498
Publisher: Oxford University Press, the Society for Neuro-Oncology and the European Association of Neuro-Oncology.
DOI: 10.1093/noajnl/vdaa028

Brain metastases with poor vascular function are susceptible to pseudoprogression after stereotactic radiation surgery

Author(s): Ingrid Digernes, Endre Grøvik, Line B. Nilsen, Cathrine Saxhaug, Oliver Geier, Edmund Reitan, Dag Ottar Sætre, Birger Breivik, Timothy Reese, Kari Dolven Jacobsen, Åslaug Helland, Kyrre Eeg Emblem
Published in: Advances in Radiation Oncology, 3/4, 2018, Page(s) 559-567, ISSN 2452-1094
Publisher: Elsevier
DOI: 10.1016/j.adro.2018.05.005

Towards patient-specific modeling of brain tumor growth and formation of secondary nodes guided by DTI-MRI

Author(s): Stelios Angeli, Kyrre E. Emblem, Paulina Due-Tonnessen, Triantafyllos Stylianopoulos
Published in: NeuroImage: Clinical, 20, 2018, Page(s) 664-673, ISSN 2213-1582
Publisher: Elsevier BV
DOI: 10.1016/j.nicl.2018.08.032

Solid stress in brain tumours causes neuronal loss and neurological dysfunction and can be reversed by lithium

Author(s): Giorgio Seano, Hadi T. Nia, Kyrre E. Emblem, Meenal Datta, Jun Ren, Shanmugarajan Krishnan, Jonas Kloepper, Marco C. Pinho, William W. Ho, Mitrajit Ghosh, Vasileios Askoxylakis, Gino B. Ferraro, Lars Riedemann, Elizabeth R. Gerstner, Tracy T. Batchelor, Patrick Y. Wen, Nancy U. Lin, Alan J. Grodzinsky, Dai Fukumura, Peigen Huang, James W. Baish, Timothy P. Padera, Lance L. Munn, Rakesh K. Jain
Published in: Nature Biomedical Engineering, 3/3, 2019, Page(s) 230-245, ISSN 2157-846X
Publisher: Springer Nature Publishing AG
DOI: 10.1038/s41551-018-0334-7

GliMR: Cross-Border Collaborations to Promote Advanced MRI Biomarkers for Glioma

Author(s): Patricia Clement, Thomas Booth, Fran Borovečki, Kyrre E. Emblem, Patrícia Figueiredo, Lydiane Hirschler, Radim Jančálek, Vera C. Keil, Camille Maumet, Yelda Özsunar, Cyril Pernet, Jan Petr, Joana Pinto, Marion Smits, Esther A. H. Warnert
Published in: Journal of Medical and Biological Engineering, Dec 3, 2020, Page(s) 1–11., ISSN 1609-0985
Publisher: Biomedical Engineering Society of the R.O.C.
DOI: 10.1007/s40846-020-00582-z

Robust association between vascular habitats and patient prognosis in glioblastoma: An international multicenter study

Author(s): María Álvarez‐Torres, Javier Juan‐Albarracín, Elies Fuster‐Garcia, Fuensanta Bellvís‐Bataller, David Lorente, Gaspar Reynés, Jaime Font de Mora, Fernando Aparici‐Robles, Carlos Botella, Jose Muñoz‐Langa, Raquel Faubel, Sabina Asensio‐Cuesta, Germán A. García‐Ferrando, Eduard Chelebian, Cristina Auger, Jose Pineda, Alex Rovira, Laura Oleaga, Enrique Mollà‐Olmos, Antonio J
Published in: Journal of Magnetic Resonance Imaging, 51/5, 2020, Page(s) 1478-1486, ISSN 1053-1807
Publisher: John Wiley & Sons Inc.
DOI: 10.1002/jmri.26958

MRI Perfusion Techniques

Author(s): Kyrre E. Emblem, Christopher Larsson, Inge R. Groote, Atle Bjørnerud
Published in: Neuroimaging Techniques in Clinical Practice - Physical Concepts and Clinical Applications, 2020, Page(s) 141-164, ISBN 978-3-030-48418-7
Publisher: Springer International Publishing
DOI: 10.1007/978-3-030-48419-4_11