Imaging Perfusion Restrictions from Extracellular Solid Stress

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Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Publications

Diagnostic utility of Restriction Spectrum Imaging in the characterization of the peritumoral brain zone in glioblastoma: Analysis of overall and progression-free survival

Author(s): Latysheva A, Geier OM, Hope TR, Brunetti M, Micci F, Vik-Mo EO, Emblem KE, Server A.
Published in: Eur J Radiol., Issue Nov;132, 2020, Page(s) 109289, ISSN 2352-0477
Publisher: Elsevier Limited
DOI: 10.1016/j.ejrad.2020.109289

Vascular dysfunction promotes regional hypoxia after bevacizumab therapy in recurrent glioblastoma patients

Author(s): Elizabeth R Gerstner, Kyrre E Emblem, Yi-Fen Yen, Jorg Dietrich, Justin T Jordan, Ciprian Catana, Kevin Lou Wenchin, Jacob M Hooker, Dan G Duda, Bruce R Rosen, Jayashree Kalpathy-Cramer, Rakesh K Jain, Tracy T Batchelor
Published in: Neuro-Oncology Advances, Issue 2/1, 2020, Page(s) vdaa157, ISSN 2632-2498
Publisher: Oxford University Press
DOI: 10.1093/noajnl/vdaa157

The Impact of MRI Features and Observer Confidence on the Treatment Decision-Making for Patients with Untreated Glioma

Author(s): Paulina Due-Tønnessen, Marco C. Pinho, Kyrre E. Emblem, John K. Hald, Masafumi Kanoto, Andreas Abildgaard, Donatas Sederevicius, Inge R. Groote, Otto Rapalino, Atle Bjørnerud
Published in: Scientific Reports, Issue 9/1, 2019, ISSN 2045-2322
Publisher: Nature Publishing Group
DOI: 10.1038/s41598-019-56333-x

Handling missing MRI sequences in deep learning segmentation of brain metastases: a multicenter study

Author(s): Grøvik E, Yi D, Iv M, Tong E, Nilsen LB, Latysheva A, Saxhaug C, Jacobsen KD, Helland Å, Emblem KE, Rubin DL, Zaharchuk G.
Published in: npj Digital Medicine, Issue Feb 22;4(1), 2021, Page(s) 33, ISSN 2398-6352
Publisher: Nature
DOI: 10.1038/s41746-021-00398-4

MGMT methylation may benefit overall survival in patients with moderately vascularized glioblastomas

Author(s): Elies Fuster-Garcia, David Lorente Estellés, María del Mar Álvarez-Torres, Javier Juan-Albarracín, Eduard Chelebian, Alex Rovira, Cristina Auger Acosta, Jose Pineda, Laura Oleaga, Enrique Mollá-Olmos, Silvano Filice, Paulina Due-Tønnessen, Torstein R. Meling, Kyrre E. Emblem, Juan M. García-Gómez
Published in: European Radiology, Issue 31/3, 2021, Page(s) 1738-1747, ISSN 0938-7994
Publisher: Springer Verlag
DOI: 10.1007/s00330-020-07297-4

2.5D and 3D segmentation of brain metastases with deep learning on multinational MRI data

Author(s): Ottesen JA, Yi D, Tong E, Iv M, Latysheva A, Saxhaug C, Jacobsen KD, Helland Å, Emblem KE, Rubin DL, Bjørnerud A, Zaharchuk G, Grøvik E
Published in: Front Neuroinform, Issue Jan 18;16, 2023, Page(s) 1056068, ISSN 1662-5196
Publisher: Frontiers Research Foundation
DOI: 10.3389/fninf.2022.1056068

Bevacizumab Reduces Permeability and Concurrent Temozolomide Delivery in a Subset of Patients with Recurrent Glioblastoma

Author(s): Elizabeth R. Gerstner, Kyrre E. Emblem, Ken Chang, Bella Vakulenko-Lagun, Yi-Fen Yen, Andrew L. Beers, Jorg Dietrich, Scott R. Plotkin, Ciprian Catana, Jacob M. Hooker, Dan G. Duda, Bruce Rosen, Jayashree Kalpathy-Cramer, Rakesh K. Jain, Tracy Batchelor
Published in: Clinical Cancer Research, Issue 26/1, 2020, Page(s) 206-212, ISSN 1078-0432
Publisher: American Association for Cancer Research
DOI: 10.1158/1078-0432.ccr-19-1739

Noise dependency in vascular parameters from combined gradient-echo and spin-echo DSC MRI

Author(s): Ingrid Digernes, Line B Nilsen, Endre Grøvik, Atle Bjørnerud, Grethe Løvland, Einar Vik-Mo, Torstein R Meling, Cathrine Saxhaug, Åslaug Helland, Kari D Jacobsen, Oliver Geier, Kyrre E Emblem
Published in: Physics in Medicine & Biology, Issue 65/22, 2020, Page(s) 225020, ISSN 1361-6560
Publisher: IOP Publishing on behalf of the Institute of Physics and Engineering in Medicine (IPEM).
DOI: 10.1088/1361-6560/abb71a

The impact of EPI-based distortion correction of dynamic susceptibility contrast MRI on cerebral blood volume estimation in patients with glioblastoma

Author(s): Ivar T. Hovden, Oliver M. Geier, Ingrid Digernes, Elies Fuster-Garcia, Grethe Løvland, Einar Vik-Mo, Torstein R. Meling, Kyrre E. Emblem
Published in: European Journal of Radiology, Issue 132, 2020, Page(s) 109278, ISSN 0720-048X
Publisher: Elsevier BV
DOI: 10.1016/j.ejrad.2020.109278

Preoperative Brain Tumor Imaging: Models and Software for Segmentation and Standardized Reporting

Author(s): Bouget D, Pedersen A, Jakola AS, Kavouridis V, Emblem KE, Eijgelaar RS, Kommers I, Ardon H, Barkhof F, Bello L, Berger MS, Conti Nibali M, Furtner J, Hervey-Jumper S, Idema AJS, Kiesel B, Kloet A, Mandonnet E, Müller DMJ, Robe PA, Rossi M, Sciortino T, Van den Brink WA, Wagemakers M, Widhalm G, Witte MG, Zwinderman AH, De Witt Hamer PC, Solheim O, Reinertsen I.
Published in: Frontiers in Neurology, Issue Jul 27;13, 2022, Page(s) 932219, ISSN 1664-2295
Publisher: Frontiers Research Foundation
DOI: 10.3389/fneur.2022.932219

Vessel Type Determined by Vessel Architectural Imaging Improves Differentiation between Early Tumor Progression and Pseudoprogression in Glioblastoma

Author(s): Kim M, Park JE, Emblem K, Bjørnerud A, Kim HS.
Published in: AJNR Am J Neuroradiol., Issue Apr;42(4), 2021, Page(s) 663-670, ISSN 0195-6108
Publisher: American Society of Neuoradiology
DOI: 10.3174/ajnr.a6984

Responses in the diffusivity and vascular function of the irradiated normal brain are seen up until 18 months following SRS of brain metastases

Author(s): Line Brennhaug Nilsen, Ingrid Digernes, Endre Grøvik, Cathrine Saxhaug, Anna Latysheva, Oliver Geier, Birger Breivik, Dag Ottar Sætre, Kari Dolven Jacobsen, Åslaug Helland, Kyrre Eeg Emblem
Published in: Neuro-Oncology Advances, Issue 2/1, 2020, Page(s) vdaa028, ISSN 2632-2498
Publisher: Oxford University Press, the Society for Neuro-Oncology and the European Association of Neuro-Oncology.
DOI: 10.1093/noajnl/vdaa028

Decreased tissue stiffness in glioblastoma by MR elastography is associated with increased cerebral blood flow

Author(s): Svensson, Siri Fløgstad; Fuster i Garcia, Elies; Latysheva, Anna; Fraser-Green, Jorunn; Nordhøy, Wibeke; Darwish, Omar Isam; Hovden, Ivar Thokle; Holm, Sverre; Vik-Mo, Einar O.; Sinkus, Ralph; Emblem, Kyrre Eeg
Published in: European Journal of Radiology, Issue 147, 2021, Page(s) 110136, ISSN 2352-0477
Publisher: Elsevier Limited
DOI: 10.1016/j.ejrad.2021.110136

Advanced MR Techniques for Preoperative Glioma Characterization: Part 1

Author(s): Lydiane Hirschler, Nico Sollmann, Bárbara Schmitz‐abecassis, Joana Pinto, Fatemehsadat Arzanforoosh, Frederik Barkhof, Thomas Booth, Marta Calvo‐imirizaldu, Guilherme Cassia, Marek Chmelik, Patricia Clement, Ece Ercan, Maria A. Fernández‐seara, Julia Furtner, Elies Fuster‐garcia, Matthew Grech‐sollars, Nazmiye Tugay Guven, Gokce Hale Hatay, Golestan Karami, Vera C. Keil Mina Kim, Johan
Published in: J Magn Reson Imaging, Issue Jun;57(6), 2023, Page(s) 1655-1675, ISSN 1522-2586
Publisher: John Wiley & Sons (Wiley)
DOI: 10.1002/jmri.28662

Differential effect of vascularity between long- and short-term survivors with IDH1/2 wild-type glioblastoma

Author(s): Álvarez-Torres MDM, Fuster-García E, Reynés G, Juan-Albarracín J, Chelebian E, Oleaga L, Pineda J, Auger C, Rovira A, Emblem KE, Filice S, Mollà-Olmos E, García-Gómez JM.
Published in: NMR Biomed, Issue Apr;34(4), 2021, Page(s) e4462, ISSN 1099-1492
Publisher: John Wiley & Sons Ltd
DOI: 10.1002/nbm.4462

Advanced <scp>MR</scp> Techniques for Preoperative Glioma Characterization: Part 2

Author(s): Gilbert Hangel; Bárbara Schmitz‐Abecassis; Nico Sollmann; Joana Pinto; Fatemehsadat Arzanforoosh; Frederik Barkhof; Thomas Booth; Marta Calvo‐Imirizaldu; Guilherme Cassia; Marek Chmelik; Patricia Clement; Ece Ercan; Maria A. Fernández‐Seara; Julia Furtner; Elies Fuster‐Garcia; Matthew Grech‐Sollars; N. Tugay Guven; Gokce Hale Hatay; Golestan Karami; Vera C. Keil; Mina Kim; Johan A. F.
Published in: J Magn Reson Imaging, Issue Jun;57(6), 2023, Page(s) 1676-1695, ISSN 1522-2586
Publisher: John Wiley & Sons (Wiley)
DOI: 10.1002/jmri.28663

A Fully Automated Deep Learning Network for Brain Tumor Segmentation

Author(s): Bangalore Yogananda CG, Shah BR, Vejdani-Jahromi M, Nalawade SS, Murugesan GK, Yu FF, Pinho MC, Wagner BC, Emblem KE, Bjørnerud A, Fei B, Madhuranthakam AJ, Maldjian JA.
Published in: Tomography, Issue Jun;6(2), 2020, Page(s) 186-193, ISSN 2379-139X
Publisher: MDPI
DOI: 10.18383/j.tom.2019.00026

Hematopoietic stem-cell gene therapy is associated with restored white matter microvascular function in cerebral adrenoleukodystrophy

Author(s): Lauer A, Speroni SL, Choi M, Da X, Duncan C, McCarthy S, Krishnan V, Lusk CA, Rohde D, Hansen MB, Kalpathy-Cramer J, Loes DJ, Caruso PA, Williams DA, Mouridsen K, Emblem KE, Eichler FS, Musolino PL
Published in: Nat Commun, Issue Apr 5;14(1), 2023, Page(s) 1900, ISSN 2041-1723
Publisher: Nature Publishing Group
DOI: 10.1038/s41467-023-37262-w

Quantification of Tissue Compression Identifies High-Grade Glioma Patients with Reduced Survival

Author(s): Elies Fuster-Garcia; Ivar Thokle Hovden; Siri Fløgstad Svensson; Christopher Larsson; Jonas Vardal; Atle Bjørnerud; Kyrre E. Emblem
Published in: Cancers; Volume 14; Issue 7; Pages: 1725, Issue 14, 2022, Page(s) 1725, ISSN 2072-6694
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/cancers14071725

A systematic review on the use of quantitative imaging to detect cancer therapy adverse effects in normal-appearing brain tissue

Author(s): Petr J, Hogeboom L, Nikulin P, Wiegers E, Schroyen G, Kallehauge J, Chmelík M, Clement P, Nechifor RE, Fodor LA, De Witt Hamer PC, Barkhof F, Pernet C, Lequin M, Deprez S, Jančálek R, Mutsaerts HJMM, Pizzini FB, Emblem KE, Keil VC.
Published in: MAGMA, Issue Feb;35(1), 2022, Page(s) 163-186, ISSN 1352-8661
Publisher: Springer
DOI: 10.1007/s10334-021-00985-2

Prediction of survival and progression in glioblastoma patients using temporal perfusion changes during radiochemotherapy

Author(s): Larsson C, Groote I, Vardal J, Kleppestø M, Odland A, Brandal P, Due-Tønnessen P, Holme SS, Hope TR, Meling TR, Fosse E, Emblem KE, Bjørnerud A.
Published in: Magn Reson Imaging ., Issue May;68, 2020, Page(s) 106-112, ISSN 0730-725X
Publisher: Elsevier BV
DOI: 10.1016/j.mri.2020.01.012

Brain metastases with poor vascular function are susceptible to pseudoprogression after stereotactic radiation surgery

Author(s): Ingrid Digernes, Endre Grøvik, Line B. Nilsen, Cathrine Saxhaug, Oliver Geier, Edmund Reitan, Dag Ottar Sætre, Birger Breivik, Timothy Reese, Kari Dolven Jacobsen, Åslaug Helland, Kyrre Eeg Emblem
Published in: Advances in Radiation Oncology, Issue 3/4, 2018, Page(s) 559-567, ISSN 2452-1094
Publisher: Elsevier
DOI: 10.1016/j.adro.2018.05.005

Towards patient-specific modeling of brain tumor growth and formation of secondary nodes guided by DTI-MRI

Author(s): Stelios Angeli, Kyrre E. Emblem, Paulina Due-Tonnessen, Triantafyllos Stylianopoulos
Published in: NeuroImage: Clinical, Issue 20, 2018, Page(s) 664-673, ISSN 2213-1582
Publisher: Elsevier BV
DOI: 10.1016/j.nicl.2018.08.032

Solid stress in brain tumours causes neuronal loss and neurological dysfunction and can be reversed by lithium

Author(s): Giorgio Seano, Hadi T. Nia, Kyrre E. Emblem, Meenal Datta, Jun Ren, Shanmugarajan Krishnan, Jonas Kloepper, Marco C. Pinho, William W. Ho, Mitrajit Ghosh, Vasileios Askoxylakis, Gino B. Ferraro, Lars Riedemann, Elizabeth R. Gerstner, Tracy T. Batchelor, Patrick Y. Wen, Nancy U. Lin, Alan J. Grodzinsky, Dai Fukumura, Peigen Huang, James W. Baish, Timothy P. Padera, Lance L. Munn, Rakesh K. Jain
Published in: Nature Biomedical Engineering, Issue 3/3, 2019, Page(s) 230-245, ISSN 2157-846X
Publisher: Springer Nature Publishing AG
DOI: 10.1038/s41551-018-0334-7

MR elastography identifies regions of extracellular matrix reorganization associated with shorter survival in glioblastoma patients

Author(s): Siri Fløgstad Svensson, Skarphéðinn Halldórsson, Anna Latysheva, Elies Fuster-Garcia, Trine Hjørnevik, Jorunn Fraser-Green, Robin Anthony Birkeland Bugge, Jack Grinband, Sverre Holm, Ralph Sinkus, Einar Osland Vik-Mo, and Kyrre Eeg Emblem
Published in: Neuro-Oncology Advances, Issue Mar 5;5(1), 2023, Page(s) vdad021, ISSN 2632-2498
Publisher: Oxford University Press
DOI: 10.1093/noajnl/vdad021

Robustness of MR Elastography in the Healthy Brain: Repeatability, Reliability, and Effect of Different Reconstruction Methods

Author(s): Svensson SF, De Arcos J, Darwish OI, Fraser-Green J, Storås TH, Holm S, Vik-Mo EO, Sinkus R, Emblem KE.
Published in: J Magn Reson Imaging, Issue May;53(5), 2021, Page(s) 1510-1521, ISSN 1522-2586
Publisher: Wiley
DOI: 10.1002/jmri.27475

Phase II trial of carboplatin and bevacizumab in patients with breast cancer brain metastases

Author(s): Leone JP, Emblem KE, Weitz M, Gelman RS, Schneider BP, Freedman RA, Younger J, Pinho MC, Sorensen AG, Gerstner ER, Harris G, Krop IE, Morganstern D, Sohl J, Hu J, Kasparian E, Winer EP, Lin NU.
Published in: Breast Cancer Res, Issue Nov 30;22(1), 2020, Page(s) 131, ISSN 1465-542X
Publisher: Springer Nature
DOI: 10.1186/s13058-020-01372-w

Losartan controls immune checkpoint blocker-induced edema and improves survival in glioblastoma mouse models

Author(s): Datta M, Chatterjee S, Perez EM, Gritsch S, Roberge S, Duquette M, Chen IX, Naxerova K, Kumar AS, Ghosh M, Emblem KE, Ng MR, Ho WW, Kumar P, Krishnan S, Dong X, Speranza MC, Neagu MR, Iorgulescu JB, Huang RY, Youssef G, Reardon DA, Sharpe AH, Freeman GJ, Suvà ML, Xu L, Jain RK.
Published in: Proc Natl Acad Sci U S A, Issue Feb 7;120(6), 2023, Page(s) e2219199120, ISSN 1091-6490
Publisher: National Academies Press
DOI: 10.1073/pnas.2219199120

MRI pulse sequence integration for deep-learning-based brain metastases segmentation

Author(s): Yi D, Grøvik E, Tong E, Iv M, Emblem KE, Nilsen LB, Saxhaug C, Latysheva A, Jacobsen KD, Helland Å, Zaharchuk G, Rubin D.
Published in: Med Phys, Issue Oct;48(10), 2021, Page(s) 6020-6035, ISSN 0094-2405
Publisher: American Association of Physicists in Medicine
DOI: 10.1002/mp.15136

GliMR: Cross-Border Collaborations to Promote Advanced MRI Biomarkers for Glioma

Author(s): Patricia Clement, Thomas Booth, Fran Borovečki, Kyrre E. Emblem, Patrícia Figueiredo, Lydiane Hirschler, Radim Jančálek, Vera C. Keil, Camille Maumet, Yelda Özsunar, Cyril Pernet, Jan Petr, Joana Pinto, Marion Smits, Esther A. H. Warnert
Published in: Journal of Medical and Biological Engineering, Issue Dec 3, 2020, Page(s) 1–11., ISSN 1609-0985
Publisher: Biomedical Engineering Society of the R.O.C.
DOI: 10.1007/s40846-020-00582-z

The Open Brain Consent: Informing research participants and obtaining consent to share brain imaging data

Author(s): Bannier E, Barker G, Borghesani V, Broeckx N, Clement P, Emblem KE, Ghosh S, Glerean E, Gorgolewski KJ, Havu M, Halchenko YO, Herholz P, Hespel A, Heunis S, Hu Y, Hu CP, Huijser D, de la Iglesia Vayá M, Jancalek R, Katsaros VK, Kieseler ML, Maumet C, Moreau CA, Mutsaerts HJ, Oostenveld R, Ozturk-Isik E, Pascual Leone Espinosa N, Pellman J, Pernet CR, Pizzini FB, Trbalić AŠ, Toussaint PJ, Viscon
Published in: Hum Brain Mapp, Issue May;42(7), 2021, Page(s) 1945-1951, ISSN 1065-9471
Publisher: John Wiley & Sons Inc.
DOI: 10.1002/hbm.25351

Inducing Biomechanical Heterogeneity in Brain Tumor Modeling by MR Elastography: Effects on Tumor Growth, Vascular Density and Delivery of Therapeutics

Author(s): Harkos C, Svensson SF, Emblem KE, Stylianopoulos T.
Published in: Cancers, Issue Feb 10;14(4), 2022, Page(s) 884, ISSN 2072-6694
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/cancers14040884

Probing tumor microenvironment in patients with newly diagnosed glioblastoma during chemoradiation and adjuvant temozolomide with functional MRI

Author(s): Ly KI, Vakulenko-Lagun B, Emblem KE, Ou Y, Da X, Betensky RA, Kalpathy-Cramer J, Duda DG, Jain RK, Chi AS, Plotkin SR, Batchelor TT, Sorensen G, Rosen BR, Gerstner ER.
Published in: Sci Rep, Issue Nov 20;8(1), 2018, Page(s) 17062, ISSN 2045-2322
Publisher: Nature Publishing Group
DOI: 10.1038/s41598-018-34820-x

Robust association between vascular habitats and patient prognosis in glioblastoma: An international multicenter study

Author(s): María Álvarez‐Torres, Javier Juan‐Albarracín, Elies Fuster‐Garcia, Fuensanta Bellvís‐Bataller, David Lorente, Gaspar Reynés, Jaime Font de Mora, Fernando Aparici‐Robles, Carlos Botella, Jose Muñoz‐Langa, Raquel Faubel, Sabina Asensio‐Cuesta, Germán A. García‐Ferrando, Eduard Chelebian, Cristina Auger, Jose Pineda, Alex Rovira, Laura Oleaga, Enrique Mollà‐Olmos, Antonio J
Published in: Journal of Magnetic Resonance Imaging, Issue 51/5, 2020, Page(s) 1478-1486, ISSN 1053-1807
Publisher: John Wiley & Sons Inc.
DOI: 10.1002/jmri.26958

Structural and functional tracking in longitudinal magnetic resonance imaging of glioblastoma

Author(s): Ivar Thokle Hovden
Published in: 2023
Publisher: University of Oslo

Evaluation of functional magnetic resonance imaging in the diagnosis of brain tumors and other brain lesions for assessment of clinical efficacy

Author(s): Due-Tønnessen, Paulina B.
Published in: 2022
Publisher: University of Oslo

MR Elastography of the Brain: In healthy subjects and patients with glioblastoma

Author(s): Siri Fløgstad Svensson
Published in: 2023
Publisher: University of Oslo

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