Imaging Perfusion Restrictions from Extracellular Solid Stress

Información del proyecto

ImPRESS

Identificador del acuerdo de subvención: 758657

DOI

10.3030/758657

Proyecto cerrado

Fecha de la firma de la CE 20 Septiembre 2017

Fecha de inicio 1 Enero 2018

Fecha de finalización 31 Marzo 2023

Financiado con arreglo a

• EXCELLENT SCIENCE - European Research Council (ERC)

Coste total

€ 1 499 638,00

Aportación de la UE

€ 1 499 638,00

Coordinado por

OSLO UNIVERSITETSSYKEHUS HF
Norway

CORDIS proporciona enlaces a los documentos públicos y las publicaciones de los proyectos de los programas marco HORIZONTE.

Los enlaces a los documentos y las publicaciones de los proyectos del Séptimo Programa Marco, así como los enlaces a algunos tipos de resultados específicos, como conjuntos de datos y «software», se obtienen dinámicamente de OpenAIRE .

Publicaciones

Peer reviewed articles (34)

Diagnostic utility of Restriction Spectrum Imaging in the characterization of the peritumoral brain zone in glioblastoma: Analysis of overall and progression-free survival

Autores: Latysheva A, Geier OM, Hope TR, Brunetti M, Micci F, Vik-Mo EO, Emblem KE, Server A.
Publicado en: Eur J Radiol., Edición Nov;132, 2020, Página(s) 109289, ISSN 2352-0477
Editor: Elsevier Limited
DOI: 10.1016/j.ejrad.2020.109289

Vascular dysfunction promotes regional hypoxia after bevacizumab therapy in recurrent glioblastoma patients

Autores: Elizabeth R Gerstner, Kyrre E Emblem, Yi-Fen Yen, Jorg Dietrich, Justin T Jordan, Ciprian Catana, Kevin Lou Wenchin, Jacob M Hooker, Dan G Duda, Bruce R Rosen, Jayashree Kalpathy-Cramer, Rakesh K Jain, Tracy T Batchelor
Publicado en: Neuro-Oncology Advances, Edición 2/1, 2020, Página(s) vdaa157, ISSN 2632-2498
Editor: Oxford University Press
DOI: 10.1093/noajnl/vdaa157

The Impact of MRI Features and Observer Confidence on the Treatment Decision-Making for Patients with Untreated Glioma

Autores: Paulina Due-Tønnessen, Marco C. Pinho, Kyrre E. Emblem, John K. Hald, Masafumi Kanoto, Andreas Abildgaard, Donatas Sederevicius, Inge R. Groote, Otto Rapalino, Atle Bjørnerud
Publicado en: Scientific Reports, Edición 9/1, 2019, ISSN 2045-2322
Editor: Nature Publishing Group
DOI: 10.1038/s41598-019-56333-x

Handling missing MRI sequences in deep learning segmentation of brain metastases: a multicenter study

Autores: Grøvik E, Yi D, Iv M, Tong E, Nilsen LB, Latysheva A, Saxhaug C, Jacobsen KD, Helland Å, Emblem KE, Rubin DL, Zaharchuk G.
Publicado en: npj Digital Medicine, Edición Feb 22;4(1), 2021, Página(s) 33, ISSN 2398-6352
Editor: Nature
DOI: 10.1038/s41746-021-00398-4

MGMT methylation may benefit overall survival in patients with moderately vascularized glioblastomas

Autores: Elies Fuster-Garcia, David Lorente Estellés, María del Mar Álvarez-Torres, Javier Juan-Albarracín, Eduard Chelebian, Alex Rovira, Cristina Auger Acosta, Jose Pineda, Laura Oleaga, Enrique Mollá-Olmos, Silvano Filice, Paulina Due-Tønnessen, Torstein R. Meling, Kyrre E. Emblem, Juan M. García-Gómez
Publicado en: European Radiology, Edición 31/3, 2021, Página(s) 1738-1747, ISSN 0938-7994
Editor: Springer Verlag
DOI: 10.1007/s00330-020-07297-4

2.5D and 3D segmentation of brain metastases with deep learning on multinational MRI data

Autores: Ottesen JA, Yi D, Tong E, Iv M, Latysheva A, Saxhaug C, Jacobsen KD, Helland Å, Emblem KE, Rubin DL, Bjørnerud A, Zaharchuk G, Grøvik E
Publicado en: Front Neuroinform, Edición Jan 18;16, 2023, Página(s) 1056068, ISSN 1662-5196
Editor: Frontiers Research Foundation
DOI: 10.3389/fninf.2022.1056068

Bevacizumab Reduces Permeability and Concurrent Temozolomide Delivery in a Subset of Patients with Recurrent Glioblastoma

Autores: Elizabeth R. Gerstner, Kyrre E. Emblem, Ken Chang, Bella Vakulenko-Lagun, Yi-Fen Yen, Andrew L. Beers, Jorg Dietrich, Scott R. Plotkin, Ciprian Catana, Jacob M. Hooker, Dan G. Duda, Bruce Rosen, Jayashree Kalpathy-Cramer, Rakesh K. Jain, Tracy Batchelor
Publicado en: Clinical Cancer Research, Edición 26/1, 2020, Página(s) 206-212, ISSN 1078-0432
Editor: American Association for Cancer Research
DOI: 10.1158/1078-0432.ccr-19-1739

Noise dependency in vascular parameters from combined gradient-echo and spin-echo DSC MRI

Autores: Ingrid Digernes, Line B Nilsen, Endre Grøvik, Atle Bjørnerud, Grethe Løvland, Einar Vik-Mo, Torstein R Meling, Cathrine Saxhaug, Åslaug Helland, Kari D Jacobsen, Oliver Geier, Kyrre E Emblem
Publicado en: Physics in Medicine & Biology, Edición 65/22, 2020, Página(s) 225020, ISSN 1361-6560
Editor: IOP Publishing on behalf of the Institute of Physics and Engineering in Medicine (IPEM).
DOI: 10.1088/1361-6560/abb71a

The impact of EPI-based distortion correction of dynamic susceptibility contrast MRI on cerebral blood volume estimation in patients with glioblastoma

Autores: Ivar T. Hovden, Oliver M. Geier, Ingrid Digernes, Elies Fuster-Garcia, Grethe Løvland, Einar Vik-Mo, Torstein R. Meling, Kyrre E. Emblem
Publicado en: European Journal of Radiology, Edición 132, 2020, Página(s) 109278, ISSN 0720-048X
Editor: Elsevier BV
DOI: 10.1016/j.ejrad.2020.109278

Preoperative Brain Tumor Imaging: Models and Software for Segmentation and Standardized Reporting

Autores: Bouget D, Pedersen A, Jakola AS, Kavouridis V, Emblem KE, Eijgelaar RS, Kommers I, Ardon H, Barkhof F, Bello L, Berger MS, Conti Nibali M, Furtner J, Hervey-Jumper S, Idema AJS, Kiesel B, Kloet A, Mandonnet E, Müller DMJ, Robe PA, Rossi M, Sciortino T, Van den Brink WA, Wagemakers M, Widhalm G, Witte MG, Zwinderman AH, De Witt Hamer PC, Solheim O, Reinertsen I.
Publicado en: Frontiers in Neurology, Edición Jul 27;13, 2022, Página(s) 932219, ISSN 1664-2295
Editor: Frontiers Research Foundation
DOI: 10.3389/fneur.2022.932219

Vessel Type Determined by Vessel Architectural Imaging Improves Differentiation between Early Tumor Progression and Pseudoprogression in Glioblastoma

Autores: Kim M, Park JE, Emblem K, Bjørnerud A, Kim HS.
Publicado en: AJNR Am J Neuroradiol., Edición Apr;42(4), 2021, Página(s) 663-670, ISSN 0195-6108
Editor: American Society of Neuoradiology
DOI: 10.3174/ajnr.a6984

Responses in the diffusivity and vascular function of the irradiated normal brain are seen up until 18 months following SRS of brain metastases

Autores: Line Brennhaug Nilsen, Ingrid Digernes, Endre Grøvik, Cathrine Saxhaug, Anna Latysheva, Oliver Geier, Birger Breivik, Dag Ottar Sætre, Kari Dolven Jacobsen, Åslaug Helland, Kyrre Eeg Emblem
Publicado en: Neuro-Oncology Advances, Edición 2/1, 2020, Página(s) vdaa028, ISSN 2632-2498
Editor: Oxford University Press, the Society for Neuro-Oncology and the European Association of Neuro-Oncology.
DOI: 10.1093/noajnl/vdaa028

Decreased tissue stiffness in glioblastoma by MR elastography is associated with increased cerebral blood flow

Autores: Svensson, Siri Fløgstad; Fuster i Garcia, Elies; Latysheva, Anna; Fraser-Green, Jorunn; Nordhøy, Wibeke; Darwish, Omar Isam; Hovden, Ivar Thokle; Holm, Sverre; Vik-Mo, Einar O.; Sinkus, Ralph; Emblem, Kyrre Eeg
Publicado en: European Journal of Radiology, Edición 147, 2021, Página(s) 110136, ISSN 2352-0477
Editor: Elsevier Limited
DOI: 10.1016/j.ejrad.2021.110136

Advanced MR Techniques for Preoperative Glioma Characterization: Part 1

Autores: Lydiane Hirschler, Nico Sollmann, Bárbara Schmitz‐abecassis, Joana Pinto, Fatemehsadat Arzanforoosh, Frederik Barkhof, Thomas Booth, Marta Calvo‐imirizaldu, Guilherme Cassia, Marek Chmelik, Patricia Clement, Ece Ercan, Maria A. Fernández‐seara, Julia Furtner, Elies Fuster‐garcia, Matthew Grech‐sollars, Nazmiye Tugay Guven, Gokce Hale Hatay, Golestan Karami, Vera C. Keil Mina Kim, Johan
Publicado en: J Magn Reson Imaging, Edición Jun;57(6), 2023, Página(s) 1655-1675, ISSN 1522-2586
Editor: John Wiley & Sons (Wiley)
DOI: 10.1002/jmri.28662

Differential effect of vascularity between long- and short-term survivors with IDH1/2 wild-type glioblastoma

Autores: Álvarez-Torres MDM, Fuster-García E, Reynés G, Juan-Albarracín J, Chelebian E, Oleaga L, Pineda J, Auger C, Rovira A, Emblem KE, Filice S, Mollà-Olmos E, García-Gómez JM.
Publicado en: NMR Biomed, Edición Apr;34(4), 2021, Página(s) e4462, ISSN 1099-1492
Editor: John Wiley & Sons Ltd
DOI: 10.1002/nbm.4462

Advanced <scp>MR</scp> Techniques for Preoperative Glioma Characterization: Part 2

Autores: Gilbert Hangel; Bárbara Schmitz‐Abecassis; Nico Sollmann; Joana Pinto; Fatemehsadat Arzanforoosh; Frederik Barkhof; Thomas Booth; Marta Calvo‐Imirizaldu; Guilherme Cassia; Marek Chmelik; Patricia Clement; Ece Ercan; Maria A. Fernández‐Seara; Julia Furtner; Elies Fuster‐Garcia; Matthew Grech‐Sollars; N. Tugay Guven; Gokce Hale Hatay; Golestan Karami; Vera C. Keil; Mina Kim; Johan A. F.
Publicado en: J Magn Reson Imaging, Edición Jun;57(6), 2023, Página(s) 1676-1695, ISSN 1522-2586
Editor: John Wiley & Sons (Wiley)
DOI: 10.1002/jmri.28663

A Fully Automated Deep Learning Network for Brain Tumor Segmentation

Autores: Bangalore Yogananda CG, Shah BR, Vejdani-Jahromi M, Nalawade SS, Murugesan GK, Yu FF, Pinho MC, Wagner BC, Emblem KE, Bjørnerud A, Fei B, Madhuranthakam AJ, Maldjian JA.
Publicado en: Tomography, Edición Jun;6(2), 2020, Página(s) 186-193, ISSN 2379-139X
Editor: MDPI
DOI: 10.18383/j.tom.2019.00026

Hematopoietic stem-cell gene therapy is associated with restored white matter microvascular function in cerebral adrenoleukodystrophy

Autores: Lauer A, Speroni SL, Choi M, Da X, Duncan C, McCarthy S, Krishnan V, Lusk CA, Rohde D, Hansen MB, Kalpathy-Cramer J, Loes DJ, Caruso PA, Williams DA, Mouridsen K, Emblem KE, Eichler FS, Musolino PL
Publicado en: Nat Commun, Edición Apr 5;14(1), 2023, Página(s) 1900, ISSN 2041-1723
Editor: Nature Publishing Group
DOI: 10.1038/s41467-023-37262-w

Quantification of Tissue Compression Identifies High-Grade Glioma Patients with Reduced Survival

Autores: Elies Fuster-Garcia; Ivar Thokle Hovden; Siri Fløgstad Svensson; Christopher Larsson; Jonas Vardal; Atle Bjørnerud; Kyrre E. Emblem
Publicado en: Cancers; Volume 14; Edición 7; Pages: 1725, Edición 14, 2022, Página(s) 1725, ISSN 2072-6694
Editor: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/cancers14071725

A systematic review on the use of quantitative imaging to detect cancer therapy adverse effects in normal-appearing brain tissue

Autores: Petr J, Hogeboom L, Nikulin P, Wiegers E, Schroyen G, Kallehauge J, Chmelík M, Clement P, Nechifor RE, Fodor LA, De Witt Hamer PC, Barkhof F, Pernet C, Lequin M, Deprez S, Jančálek R, Mutsaerts HJMM, Pizzini FB, Emblem KE, Keil VC.
Publicado en: MAGMA, Edición Feb;35(1), 2022, Página(s) 163-186, ISSN 1352-8661
Editor: Springer
DOI: 10.1007/s10334-021-00985-2

Prediction of survival and progression in glioblastoma patients using temporal perfusion changes during radiochemotherapy

Autores: Larsson C, Groote I, Vardal J, Kleppestø M, Odland A, Brandal P, Due-Tønnessen P, Holme SS, Hope TR, Meling TR, Fosse E, Emblem KE, Bjørnerud A.
Publicado en: Magn Reson Imaging ., Edición May;68, 2020, Página(s) 106-112, ISSN 0730-725X
Editor: Elsevier BV
DOI: 10.1016/j.mri.2020.01.012

Brain metastases with poor vascular function are susceptible to pseudoprogression after stereotactic radiation surgery

Autores: Ingrid Digernes, Endre Grøvik, Line B. Nilsen, Cathrine Saxhaug, Oliver Geier, Edmund Reitan, Dag Ottar Sætre, Birger Breivik, Timothy Reese, Kari Dolven Jacobsen, Åslaug Helland, Kyrre Eeg Emblem
Publicado en: Advances in Radiation Oncology, Edición 3/4, 2018, Página(s) 559-567, ISSN 2452-1094
Editor: Elsevier
DOI: 10.1016/j.adro.2018.05.005

Towards patient-specific modeling of brain tumor growth and formation of secondary nodes guided by DTI-MRI

Autores: Stelios Angeli, Kyrre E. Emblem, Paulina Due-Tonnessen, Triantafyllos Stylianopoulos
Publicado en: NeuroImage: Clinical, Edición 20, 2018, Página(s) 664-673, ISSN 2213-1582
Editor: Elsevier BV
DOI: 10.1016/j.nicl.2018.08.032

Solid stress in brain tumours causes neuronal loss and neurological dysfunction and can be reversed by lithium

Autores: Giorgio Seano, Hadi T. Nia, Kyrre E. Emblem, Meenal Datta, Jun Ren, Shanmugarajan Krishnan, Jonas Kloepper, Marco C. Pinho, William W. Ho, Mitrajit Ghosh, Vasileios Askoxylakis, Gino B. Ferraro, Lars Riedemann, Elizabeth R. Gerstner, Tracy T. Batchelor, Patrick Y. Wen, Nancy U. Lin, Alan J. Grodzinsky, Dai Fukumura, Peigen Huang, James W. Baish, Timothy P. Padera, Lance L. Munn, Rakesh K. Jain
Publicado en: Nature Biomedical Engineering, Edición 3/3, 2019, Página(s) 230-245, ISSN 2157-846X
Editor: Springer Nature Publishing AG
DOI: 10.1038/s41551-018-0334-7

MR elastography identifies regions of extracellular matrix reorganization associated with shorter survival in glioblastoma patients

Autores: Siri Fløgstad Svensson, Skarphéðinn Halldórsson, Anna Latysheva, Elies Fuster-Garcia, Trine Hjørnevik, Jorunn Fraser-Green, Robin Anthony Birkeland Bugge, Jack Grinband, Sverre Holm, Ralph Sinkus, Einar Osland Vik-Mo, and Kyrre Eeg Emblem
Publicado en: Neuro-Oncology Advances, Edición Mar 5;5(1), 2023, Página(s) vdad021, ISSN 2632-2498
Editor: Oxford University Press
DOI: 10.1093/noajnl/vdad021

Robustness of MR Elastography in the Healthy Brain: Repeatability, Reliability, and Effect of Different Reconstruction Methods

Autores: Svensson SF, De Arcos J, Darwish OI, Fraser-Green J, Storås TH, Holm S, Vik-Mo EO, Sinkus R, Emblem KE.
Publicado en: J Magn Reson Imaging, Edición May;53(5), 2021, Página(s) 1510-1521, ISSN 1522-2586
Editor: Wiley
DOI: 10.1002/jmri.27475

Phase II trial of carboplatin and bevacizumab in patients with breast cancer brain metastases

Autores: Leone JP, Emblem KE, Weitz M, Gelman RS, Schneider BP, Freedman RA, Younger J, Pinho MC, Sorensen AG, Gerstner ER, Harris G, Krop IE, Morganstern D, Sohl J, Hu J, Kasparian E, Winer EP, Lin NU.
Publicado en: Breast Cancer Res, Edición Nov 30;22(1), 2020, Página(s) 131, ISSN 1465-542X
Editor: Springer Nature
DOI: 10.1186/s13058-020-01372-w

Losartan controls immune checkpoint blocker-induced edema and improves survival in glioblastoma mouse models

Autores: Datta M, Chatterjee S, Perez EM, Gritsch S, Roberge S, Duquette M, Chen IX, Naxerova K, Kumar AS, Ghosh M, Emblem KE, Ng MR, Ho WW, Kumar P, Krishnan S, Dong X, Speranza MC, Neagu MR, Iorgulescu JB, Huang RY, Youssef G, Reardon DA, Sharpe AH, Freeman GJ, Suvà ML, Xu L, Jain RK.
Publicado en: Proc Natl Acad Sci U S A, Edición Feb 7;120(6), 2023, Página(s) e2219199120, ISSN 1091-6490
Editor: National Academies Press
DOI: 10.1073/pnas.2219199120

MRI pulse sequence integration for deep-learning-based brain metastases segmentation

Autores: Yi D, Grøvik E, Tong E, Iv M, Emblem KE, Nilsen LB, Saxhaug C, Latysheva A, Jacobsen KD, Helland Å, Zaharchuk G, Rubin D.
Publicado en: Med Phys, Edición Oct;48(10), 2021, Página(s) 6020-6035, ISSN 0094-2405
Editor: American Association of Physicists in Medicine
DOI: 10.1002/mp.15136

GliMR: Cross-Border Collaborations to Promote Advanced MRI Biomarkers for Glioma

Autores: Patricia Clement, Thomas Booth, Fran Borovečki, Kyrre E. Emblem, Patrícia Figueiredo, Lydiane Hirschler, Radim Jančálek, Vera C. Keil, Camille Maumet, Yelda Özsunar, Cyril Pernet, Jan Petr, Joana Pinto, Marion Smits, Esther A. H. Warnert
Publicado en: Journal of Medical and Biological Engineering, Edición Dec 3, 2020, Página(s) 1–11., ISSN 1609-0985
Editor: Biomedical Engineering Society of the R.O.C.
DOI: 10.1007/s40846-020-00582-z

The Open Brain Consent: Informing research participants and obtaining consent to share brain imaging data

Autores: Bannier E, Barker G, Borghesani V, Broeckx N, Clement P, Emblem KE, Ghosh S, Glerean E, Gorgolewski KJ, Havu M, Halchenko YO, Herholz P, Hespel A, Heunis S, Hu Y, Hu CP, Huijser D, de la Iglesia Vayá M, Jancalek R, Katsaros VK, Kieseler ML, Maumet C, Moreau CA, Mutsaerts HJ, Oostenveld R, Ozturk-Isik E, Pascual Leone Espinosa N, Pellman J, Pernet CR, Pizzini FB, Trbalić AŠ, Toussaint PJ, Viscon
Publicado en: Hum Brain Mapp, Edición May;42(7), 2021, Página(s) 1945-1951, ISSN 1065-9471
Editor: John Wiley & Sons Inc.
DOI: 10.1002/hbm.25351

Inducing Biomechanical Heterogeneity in Brain Tumor Modeling by MR Elastography: Effects on Tumor Growth, Vascular Density and Delivery of Therapeutics

Autores: Harkos C, Svensson SF, Emblem KE, Stylianopoulos T.
Publicado en: Cancers, Edición Feb 10;14(4), 2022, Página(s) 884, ISSN 2072-6694
Editor: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/cancers14040884

Probing tumor microenvironment in patients with newly diagnosed glioblastoma during chemoradiation and adjuvant temozolomide with functional MRI

Autores: Ly KI, Vakulenko-Lagun B, Emblem KE, Ou Y, Da X, Betensky RA, Kalpathy-Cramer J, Duda DG, Jain RK, Chi AS, Plotkin SR, Batchelor TT, Sorensen G, Rosen BR, Gerstner ER.
Publicado en: Sci Rep, Edición Nov 20;8(1), 2018, Página(s) 17062, ISSN 2045-2322
Editor: Nature Publishing Group
DOI: 10.1038/s41598-018-34820-x

Robust association between vascular habitats and patient prognosis in glioblastoma: An international multicenter study

Autores: María Álvarez‐Torres, Javier Juan‐Albarracín, Elies Fuster‐Garcia, Fuensanta Bellvís‐Bataller, David Lorente, Gaspar Reynés, Jaime Font de Mora, Fernando Aparici‐Robles, Carlos Botella, Jose Muñoz‐Langa, Raquel Faubel, Sabina Asensio‐Cuesta, Germán A. García‐Ferrando, Eduard Chelebian, Cristina Auger, Jose Pineda, Alex Rovira, Laura Oleaga, Enrique Mollà‐Olmos, Antonio J
Publicado en: Journal of Magnetic Resonance Imaging, Edición 51/5, 2020, Página(s) 1478-1486, ISSN 1053-1807
Editor: John Wiley & Sons Inc.
DOI: 10.1002/jmri.26958

Thesis and dissertations (3)

Structural and functional tracking in longitudinal magnetic resonance imaging of glioblastoma

Autores: Ivar Thokle Hovden
Publicado en: 2023
Editor: University of Oslo

Evaluation of functional magnetic resonance imaging in the diagnosis of brain tumors and other brain lesions for assessment of clinical efficacy

Autores: Due-Tønnessen, Paulina B.
Publicado en: 2022
Editor: University of Oslo

MR Elastography of the Brain: In healthy subjects and patients with glioblastoma

Autores: Siri Fløgstad Svensson
Publicado en: 2023
Editor: University of Oslo